ID   PHS_LEGPL               Reviewed;         113 AA.
AC   Q5WV42;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase;
DE            Short=PHS;
DE            EC=4.2.1.96;
DE   AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase;
DE   AltName: Full=Pterin carbinolamine dehydratase;
DE            Short=PCD;
GN   OrderedLocusNames=lpl1975;
OS   Legionella pneumophila (strain Lens).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=297245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15467720; DOI=10.1038/ng1447;
RA   Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L.,
RA   Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F.,
RA   Etienne J., Glaser P., Buchrieser C.;
RT   "Evidence in the Legionella pneumophila genome for exploitation of
RT   host cell functions and high genome plasticity.";
RL   Nat. Genet. 36:1165-1173(2004).
CC   -!- CATALYTIC ACTIVITY: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-
CC       5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-
CC       dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.
CC   -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine
CC       dehydratase family.
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DR   EMBL; CR628337; CAH16215.1; -; Genomic_DNA.
DR   RefSeq; YP_127311.1; -.
DR   GeneID; 3113926; -.
DR   GenomeReviews; CR628337_GR; lpl1975.
DR   KEGG; lpf:lpl1975; -.
DR   NMPDR; fig|297245.3.peg.2422; -.
DR   LegioList; lpl1975; -.
DR   HOGENOM; Q5WV42; -.
DR   OMA; Q5WV42; ILTEWGK.
DR   BioCyc; LPNE297245:LPL1975-MON; -.
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydrat...; IEA:HAMAP.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00434; -; 1.
DR   InterPro; IPR001533; Trans/pterin_deHydtase.
DR   Gene3D; G3DSA:3.30.1360.20; Trans_pterinDh; 1.
DR   PANTHER; PTHR12599; Trans_pterinDh; 1.
DR   Pfam; PF01329; Pterin_4a; 1.
DR   ProDom; PD007262; Trans_pterinDh; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Lyase.
FT   CHAIN         1    113       Putative pterin-4-alpha-carbinolamine
FT                                dehydratase.
FT                                /FTId=PRO_0000231450.
SQ   SEQUENCE   113 AA;  12882 MW;  CFEB94D8A6D01722 CRC64;
     MTSDLSSKHC ESCEGIGAAL NSEQIKNLLP QLNTKWEVTE DNRIIKRAFS FKNFYETMAF
     VNAIAWIANI ENHHPDLEVG YNYCHVHFMT HALNGLTHND FICAAKIDKL LVD
//