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Protein

Guanylate kinase

Gene

gmk

Organism
Legionella pneumophila (strain Lens)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 21ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:lpl1987
OrganismiLegionella pneumophila (strain Lens)
Taxonomic identifieri297245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000002517 Componenti: Chromosome

Organism-specific databases

LegioListilpl1987

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705551 – 209Guanylate kinaseAdd BLAST209

Structurei

3D structure databases

ProteinModelPortaliQ5WV30
SMRiQ5WV30
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 185Guanylate kinase-likeUniRule annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5WV30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSDNSGNLY IVAAPSGGGK TSLVKKLIEM VGEIEVSVSH TTRPMRPGEK
60 70 80 90 100
EGVDYFFIDE EQFISMVNEG AFIEHAKVFN HWYGTSVAQI NKRLQFGIDV
110 120 130 140 150
VLDIDWQGAE QIRHAYPDAV SVFIIPPSLD ALKERLMNRR QDKDNVISER
160 170 180 190 200
MTKAQDELGH YPEFDYLIVN DDFEKAAMEL QSIVIANRLR IEKQANKQAK

LLSFLLSSQ
Length:209
Mass (Da):23,692
Last modified:November 23, 2004 - v1
Checksum:iFAD2FD489C6D0BBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR628337 Genomic DNA Translation: CAH16227.1
RefSeqiWP_011215973.1, NC_006369.1

Genome annotation databases

EnsemblBacteriaiCAH16227; CAH16227; lpl1987
KEGGilpf:lpl1987

Similar proteinsi

Entry informationi

Entry nameiKGUA_LEGPL
AccessioniPrimary (citable) accession number: Q5WV30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: November 23, 2004
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome