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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Legionella pneumophila (strain Lens)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:lpl2008
OrganismiLegionella pneumophila (strain Lens)
Taxonomic identifieri297245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000002517 Componenti: Chromosome

Organism-specific databases

LegioListilpl2008.

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420371 – 589Arginine--tRNA ligaseAdd BLAST589

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ5WV09.
SMRiQ5WV09.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi131 – 141"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5WV09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSMKAIIEY LLKQALINLQ QSGEMPIDLE IEIKVENAKD PAHGDYATNL
60 70 80 90 100
ALVLAKPCRQ APKVLAERLV AVIPADPSVE KIEIAGAGFI NFFMRSTARS
110 120 130 140 150
LIISEILNKG KEFGQGNLGQ SQKVLIEFVS ANPTGPLHVG HGRGAAFGAT
160 170 180 190 200
LGNVLKAAGY DVTLEYYVND AGRQMNILAV SVWLRYLELA GEPIAFPANG
210 220 230 240 250
YKGQYVYEIA QEMWSEQGNQ FVHPWISVVD NLPADEPEGG DKETYIDAII
260 270 280 290 300
ARAQSLLGKD GFANFHQHAL KTVLDDIKDD LQAFGVRFDS WFSEQSLFED
310 320 330 340 350
GSIGKGIQAL KDRGHTYERE GALWFRATDF GDEKDRVLVR ANGQTTYFAS
360 370 380 390 400
DVAYHWNKYD RGFDRVIDIF GADHHGYVTR IKTAVKALGH DESALDVILV
410 420 430 440 450
QFAILYRGGD RVQMSTRSGS FVTLRELREE VGNDAARYFY VARKPEQHMD
460 470 480 490 500
FDLDLAKSES SDNPVYYIQY AHARICSVLR QLKERGLKWD KDMGLKNLDL
510 520 530 540 550
LEQQHEATLI SLIARYPEVI QSAAASCEPH QLAYYLRELA NGLHSYYNAI
560 570 580
QLLCEQEQLR CARLCLLESV RQVLNNGLAI LGVSAPESM
Length:589
Mass (Da):65,878
Last modified:November 23, 2004 - v1
Checksum:i86513C13E1E82041
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR628337 Genomic DNA. Translation: CAH16248.1.

Genome annotation databases

EnsemblBacteriaiCAH16248; CAH16248; lpl2008.
KEGGilpf:lpl2008.

Similar proteinsi

Entry informationi

Entry nameiSYR_LEGPL
AccessioniPrimary (citable) accession number: Q5WV09
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: August 30, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families