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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Legionella pneumophila (strain Lens)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:lpl2853
OrganismiLegionella pneumophila (strain Lens)
Taxonomic identifieri297245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000002517 Componenti: Chromosome

Organism-specific databases

LegioListilpl2853

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001979971 – 276Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST276

Structurei

3D structure databases

ProteinModelPortaliQ5WSM5
SMRiQ5WSM5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q5WSM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDYAIGDIQ GCYDPLQRLL ELIDFNEKDD CLWFVGDLVN RGPDSLAVLR
60 70 80 90 100
FIYSLPVKPK ITLGNHDLHL LGLLFGGQPW KGHDDTLEEV MLADDGEELG
110 120 130 140 150
HWLRKQSLLC RSSELNIVMC HAGIAPLWDL SKAVGLANEL EAVLSGDSYH
160 170 180 190 200
EFFAQMYGNK PDIWSDDLVG LDRLRVITNY FTRMRYCDAH GRLDLGYKGT
210 220 230 240 250
LSKAPNHLYP WFEVPCRKEI EMDIVFGHWA ALMGRSSHPR IHAIDTGCLW
260 270
GGQLTALRLQ DRQRFSVPGY GVSRFE
Length:276
Mass (Da):31,363
Last modified:November 23, 2004 - v1
Checksum:iB2620548AE2E37F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR628337 Genomic DNA Translation: CAH17097.1

Genome annotation databases

EnsemblBacteriaiCAH17097; CAH17097; lpl2853
KEGGilpf:lpl2853

Similar proteinsi

Entry informationi

Entry nameiAPAH_LEGPL
AccessioniPrimary (citable) accession number: Q5WSM5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: November 23, 2004
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health