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Q5WQZ9 (KBX34_OPICA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Opiscorpine-4
OrganismOpistophthalmus carinatus (African yellow leg scorpion)
Taxonomic identifier190115 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaScorpionesIuridaScorpionoideaScorpionidaeScorpioninaeOpistophthalmus

Protein attributes

Sequence length95 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Has antimicrobial activity against yeasts and bacteria By similarity.

Subcellular location

Secreted By similarity.

Tissue specificity

Expressed by the venom gland.

Sequence similarities

Belongs to the long chain scorpion toxin family. Class 3 subfamily.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionAntibiotic
Antimicrobial
Fungicide
   PTMDisulfide bond
Gene Ontology (GO)
   Biological_processdefense response to bacterium

Inferred from electronic annotation. Source: UniProtKB-KW

defense response to fungus

Inferred from electronic annotation. Source: UniProtKB-KW

killing of cells of other organism

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 9576Opiscorpine-4
PRO_5000092274

Amino acid modifications

Disulfide bond58 ↔ 82 By similarity
Disulfide bond68 ↔ 87 By similarity
Disulfide bond72 ↔ 89 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5WQZ9 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 95EFA86F1CB9475F

FASTA9510,397
        10         20         30         40         50         60 
MNNKLTALIF LGLLAIASCK WLNEKSIQNK IDEKIGKNFL GGMAKAVVHK LAKNEFMCVA 

        70         80         90 
NIDMTKSCDT HCQKASGEKG YCHGTKCKCG VPLSY 

« Hide

References

[1]"The scorpine family of defensins: gene structure, alternative polyadenylation and fold recognition."
Zhu S., Tytgat J.
Cell. Mol. Life Sci. 61:1751-1763(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Venom gland.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY423485 mRNA. Translation: AAQ94356.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR003614. Scorpion_toxin-like.
[Graphical view]
SUPFAMSSF57095. SSF57095. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKBX34_OPICA
AccessionPrimary (citable) accession number: Q5WQZ9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: November 23, 2004
Last modified: October 16, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Scorpion potassium channel toxins

Nomenclature of scorpion potassium channel toxins and list of entries