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Protein

Opiscorpine-3

Gene
N/A
Organism
Opistophthalmus carinatus (African yellow leg scorpion)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Has antimicrobial activity against yeasts and bacteria.By similarity

GO - Biological processi

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Fungicide

Names & Taxonomyi

Protein namesi
Recommended name:
Opiscorpine-3
OrganismiOpistophthalmus carinatus (African yellow leg scorpion)
Taxonomic identifieri190115 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaScorpionesIuridaScorpionoideaScorpionidaeScorpioninaeOpistophthalmus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500009227620 – 95Opiscorpine-3Add BLAST76

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi58 ↔ 82By similarity
Disulfide bondi68 ↔ 87By similarity
Disulfide bondi72 ↔ 89By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Structurei

3D structure databases

SMRiQ5WQZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiView protein in InterPro
IPR029237. Long_scorpion_toxin.
IPR003614. Scorpion_toxin-like.
PfamiView protein in Pfam
PF14866. Toxin_38. 1 hit.
SUPFAMiSSF57095. SSF57095. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5WQZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNKLTALIF LGLLAIASCK WLNEKSIQNK IDEKIGKNFL GGMAKAVVHK
60 70 80 90
LAKNEFMCVA NVDMTKSCDT HCQKASGEKG YCHGTKCKCG VPLSY
Length:95
Mass (Da):10,383
Last modified:November 23, 2004 - v1
Checksum:i95FC10548CB9475F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY423487 Genomic DNA. Translation: AAQ94358.1.
AY423484 mRNA. Translation: AAQ94355.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiKBX33_OPICA
AccessioniPrimary (citable) accession number: Q5WQZ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: November 23, 2004
Last modified: March 15, 2017
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Scorpion potassium channel toxins
    Nomenclature of scorpion potassium channel toxins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families