Q5WLS4 (RL1_BACSK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	ABC0138

Organism

Bacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]

Taxonomic identifier

66692 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP MF_01318_B Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP MF_01318_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	50S ribosomal protein L1 HAMAP MF_01318_B		PRO_0000125614

Sequences

	Sequence		Length	Mass (Da)
	Q5WLS4 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 880B01DC5BC8AB6F	FASTA	231	24,910
	10 20 30 40 50 60 MAKKGKKYAD ALKLVDRDTA YQAEEALELV KKTSVAKFDE TVEVAVRLGV DPKKADQQIR 70 80 90 100 110 120 GAVVLPHGTG KTQRVLVFAK GEKAKEAEAA GADYVGEDDL INKINQGWFD FDVIVATPDM 130 140 150 160 170 180 MAQVGRLGRV LGPKGLMPNP KTGTVTFDVT KAVEEIKAGK VEYRVDKSGN IHVPIGKVSF 190 200 210 220 230 DTPKLLENFQ TIVETLHKVK PAAAKGTYVK NIAVASTMGP GIRVTTTAFA K

References

[1]

"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16." Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KSM-K16.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006627 Genomic DNA. Translation: BAD62681.1.
RefSeq	YP_173642.1. NC_006582.1.
3D structure databases
ProteinModelPortal	Q5WLS4.
SMR	Q5WLS4. Positions 6-226.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WLS4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000047885; EBBACP00000046646; EBBACG00000047876.
GeneID	3201526.
GenomeReviews	Gene locus ABC0138 in contig AP006627_GR.
KEGG	bcl:ABC0138.
NMPDR	fig|66692.3.peg.1188.
PATRIC	18919454. VBIBacCla58185_0144.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0081.
GeneTree	EBGT00050000000900.
HOGENOM	HBG297400.
OMA	KAGTVTM.
ProtClustDB	PRK05424.
Enzyme and pathway databases
BioCyc	BCLA66692:ABC0138-MONOMER.
Family and domain databases
HAMAP	MF_01318_B. Ribosomal_L1_B. [Tree]
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Gene3D	G3DSA:3.30.190.20. Ribosomal_L1_2-a/b-sand. 2 hits. G3DSA:3.40.50.790. Ribosomal_L1_3-a/b-sand. 1 hit.
KO	K02863.
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. RplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_BACSK

Accession

Primary (citable) accession number: Q5WLS4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program