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Q5WL84 (GLSA_BACSK) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:ABC0329
OrganismBacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]
Taxonomic identifier66692 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Glutaminase HAMAP-Rule MF_00313
PRO_1000048325

Sites

Binding site651Substrate By similarity
Binding site1171Substrate By similarity
Binding site1621Substrate By similarity
Binding site1691Substrate By similarity
Binding site1931Substrate By similarity
Binding site2451Substrate By similarity
Binding site2631Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5WL84 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: FDCD01880A3D4E53

FASTA30933,467
        10         20         30         40         50         60 
MLCRSNDELE LLISQARAFA GQGEVAQYIP ALAAAHKHEL SVALYYPDGK GFMAGDTEEN 

        70         80         90        100        110        120 
FTLQSISKVL SLALALIDQG EECVFTRVGK EPTGDPFNSI AKLETNKPSK PLNPMINAGA 

       130        140        150        160        170        180 
LAVTHMIKGN TAGERFERLL DFIRCLTGNE TITYNKEIAK SEFETAHLNR ALVYFMKEHG 

       190        200        210        220        230        240 
VIDEDVEELM DLYTKQCAIE MNCIDLARVG CVLAMDGCDP DTGKQLLPID VARICKTFMV 

       250        260        270        280        290        300 
TCGMYNASGE FAINVGIPAK SGVSGGIMGA VPKKCGIGIC GPSLDEKGNS IAGIKLLEMM 


AKRYSLSMF 

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References

[1]"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KSM-K16.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006627 Genomic DNA. Translation: BAD62871.1.
RefSeqYP_173832.1. NC_006582.1.

3D structure databases

ProteinModelPortalQ5WL84.
SMRQ5WL84. Positions 2-309.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING66692.ABC0329.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD62871; BAD62871; ABC0329.
GeneID3204185.
KEGGbcl:ABC0329.
PATRIC18919870. VBIBacCla58185_0340.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycBCLA66692:GHMP-362-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_BACSK
AccessionPrimary (citable) accession number: Q5WL84
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 23, 2004
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families