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Q5WL84

- GLSA_BACSK

UniProt

Q5WL84 - GLSA_BACSK

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Protein

Glutaminase

Gene

glsA

Organism
Bacillus clausii (strain KSM-K16)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei65 – 651SubstrateUniRule annotation
Binding sitei117 – 1171SubstrateUniRule annotation
Binding sitei162 – 1621SubstrateUniRule annotation
Binding sitei169 – 1691SubstrateUniRule annotation
Binding sitei193 – 1931SubstrateUniRule annotation
Binding sitei245 – 2451SubstrateUniRule annotation
Binding sitei263 – 2631Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBCLA66692:GHMP-362-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:ABC0329
OrganismiBacillus clausii (strain KSM-K16)
Taxonomic identifieri66692 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001168: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309GlutaminasePRO_1000048325Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi66692.ABC0329.

Structurei

3D structure databases

ProteinModelPortaliQ5WL84.
SMRiQ5WL84. Positions 2-309.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5WL84-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLCRSNDELE LLISQARAFA GQGEVAQYIP ALAAAHKHEL SVALYYPDGK
60 70 80 90 100
GFMAGDTEEN FTLQSISKVL SLALALIDQG EECVFTRVGK EPTGDPFNSI
110 120 130 140 150
AKLETNKPSK PLNPMINAGA LAVTHMIKGN TAGERFERLL DFIRCLTGNE
160 170 180 190 200
TITYNKEIAK SEFETAHLNR ALVYFMKEHG VIDEDVEELM DLYTKQCAIE
210 220 230 240 250
MNCIDLARVG CVLAMDGCDP DTGKQLLPID VARICKTFMV TCGMYNASGE
260 270 280 290 300
FAINVGIPAK SGVSGGIMGA VPKKCGIGIC GPSLDEKGNS IAGIKLLEMM

AKRYSLSMF
Length:309
Mass (Da):33,467
Last modified:November 23, 2004 - v1
Checksum:iFDCD01880A3D4E53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006627 Genomic DNA. Translation: BAD62871.1.
RefSeqiYP_173832.1. NC_006582.1.

Genome annotation databases

EnsemblBacteriaiBAD62871; BAD62871; ABC0329.
GeneIDi3204185.
KEGGibcl:ABC0329.
PATRICi18919870. VBIBacCla58185_0340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006627 Genomic DNA. Translation: BAD62871.1 .
RefSeqi YP_173832.1. NC_006582.1.

3D structure databases

ProteinModelPortali Q5WL84.
SMRi Q5WL84. Positions 2-309.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 66692.ABC0329.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD62871 ; BAD62871 ; ABC0329 .
GeneIDi 3204185.
KEGGi bcl:ABC0329.
PATRICi 18919870. VBIBacCla58185_0340.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci BCLA66692:GHMP-362-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
    Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KSM-K16.

Entry informationi

Entry nameiGLSA_BACSK
AccessioniPrimary (citable) accession number: Q5WL84
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 23, 2004
Last modified: October 1, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3