Reviewed, UniProtKB/Swiss-Prot Q5WL05 (ARAA_BACSK)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	ABC0408

Organism

Bacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]

Taxonomic identifier

66692 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 486	486	L-arabinose isomerase HAMAP MF_00519		PRO_0000198380
Sites
	Metal binding	299	1	Manganese By similarity
	Metal binding	324	1	Manganese By similarity
	Metal binding	341	1	Manganese By similarity
	Metal binding	440	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5WL05-1 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: ABB7332B94A761CE	FASTA	486	54,729
	10 20 30 40 50 60 MHKQGKYQFW FITGSQPLYG QEALDEVAAH SKAMVERLKE KLPEELVLKP VASSPERILE 70 80 90 100 110 120 LFRAANGDNN CAGIITWMHT FSPAKMWIAG LNELNKPMLH FHTQYNRDIP WGDIDMDFMN 130 140 150 160 170 180 LNQSAHGDRE FGFMVSRMNI DRKVVAGHWQ DARVMKRIGD WMKTVNAYQE SKQLKIARFG 190 200 210 220 230 240 DNMREVAVTE GDKVEAQIKL GWSVSGFGIG DLVEVINSVS TEEVNALMDE YRSLYTFHRD 250 260 270 280 290 300 ANIAAVEEQA RIEIGIERFL QQGDFRAFST TFEDLHGMKQ LPGLAVQRLM AKGYGFAGEG 310 320 330 340 350 360 DWKTAALLRV LKVLAGNVGT SFMEDYTNHL EPGQEMILGS HMLEVCPTIS AQKPEIVVAP 370 380 390 400 410 420 LSMGNREDPA RLVFKGKAGR ALNAALIDMG SRFRLVANEV EAVENPHDMP KLPVASVLWK 430 440 450 460 470 480 PLPSFSEATE AWIYAGGAHH TVFSYEISKE QLADWASLMG IECIVIDDQS NVGQVRKELF WNRRAY

References

[1]	"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16." Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006627 Genomic DNA. Translation: BAD62950.1.
RefSeq	YP_173911.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WL05.
Genome annotation databases
GeneID	3201705.
GenomeReviews	Gene locus ABC0408 in contig AP006627_GR.
KEGG	bcl:ABC0408.
NMPDR	fig|66692.3.peg.220.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5WL05.
OMA	EVCPTIA.
Enzyme and pathway databases
BioCyc	BCLA66692:ABC0408-MON.
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_BACSK

Accession

Primary (citable) accession number: Q5WL05

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	November 23, 2004
Last modified:	November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)