SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5WKY6

- IOLG_BACSK

UniProt

Q5WKY6 - IOLG_BACSK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase
Gene
iolG, ABC0427
Organism
Bacillus clausii (strain KSM-K16)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively By similarity.UniRule annotation

Catalytic activityi

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.UniRule annotation
1D-chiro-inositol + NAD+ = 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. inositol 2-dehydrogenase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. inositol catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciBCLA66692:GHMP-460-MONOMER.
UniPathwayiUPA00076; UER00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase (EC:1.1.1.18, EC:1.1.1.369)
Alternative name(s):
Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase
Short name:
MI 2-dehydrogenase/DCI 3-dehydrogenase
Gene namesi
Name:iolG
Ordered Locus Names:ABC0427
OrganismiBacillus clausii (strain KSM-K16)
Taxonomic identifieri66692 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001168: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenaseUniRule annotation
PRO_0000352555Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi66692.ABC0427.

Structurei

3D structure databases

ProteinModelPortaliQ5WKY6.

Family & Domainsi

Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.

Phylogenomic databases

eggNOGiCOG0673.
HOGENOMiHOG000227439.
KOiK00010.
OMAiGDNYTTD.
OrthoDBiEOG6GFGMS.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01671. IolG.
InterProiIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5WKY6-1 [UniParc]FASTAAdd to Basket

« Hide

MTVRVGVIGT GAIGQDHIRR LECKLSGAKV TAVTDVNQDL ARKVANTYAK    50
QATVYANDRE LIAARDVDAV LVASWGPAHE ASVLAALEAG KRVFCEKPLA 100
TTADGCMRIV EAEMAHGKRL VQVGFMRRFD SGYLQLKQAL EQELVGEPLM 150
VRCIHRNVES AESYTTDMAI TDTLIHEIDV LHWLLNDEYQ HVRVLYPKKT 200
KHALPHLQDP QLVLLETKKG VIIQAEIFVN CKYGYDIQCE IAGEEGVISL 250
PDVPAVRLCS NGRKGTEVLQ DWKKRFEAAY DVELQAFIDD GLKDEPASGP 300
SAWDGYVAAV TADACVKAQE SGREESIELP KKPAFYQHSA ATPEQV 346
Length:346
Mass (Da):38,171
Last modified:November 23, 2004 - v1
Checksum:i3BBDA0E986095B37
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006627 Genomic DNA. Translation: BAD62969.1.
RefSeqiYP_173930.1. NC_006582.1.

Genome annotation databases

EnsemblBacteriaiBAD62969; BAD62969; ABC0427.
GeneIDi3201776.
KEGGibcl:ABC0427.
PATRICi18920082. VBIBacCla58185_0446.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006627 Genomic DNA. Translation: BAD62969.1 .
RefSeqi YP_173930.1. NC_006582.1.

3D structure databases

ProteinModelPortali Q5WKY6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 66692.ABC0427.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD62969 ; BAD62969 ; ABC0427 .
GeneIDi 3201776.
KEGGi bcl:ABC0427.
PATRICi 18920082. VBIBacCla58185_0446.

Phylogenomic databases

eggNOGi COG0673.
HOGENOMi HOG000227439.
KOi K00010.
OMAi GDNYTTD.
OrthoDBi EOG6GFGMS.

Enzyme and pathway databases

UniPathwayi UPA00076 ; UER00143 .
BioCyci BCLA66692:GHMP-460-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_01671. IolG.
InterProi IPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view ]
Pfami PF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
    Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KSM-K16.

Entry informationi

Entry nameiIOLG_BACSK
AccessioniPrimary (citable) accession number: Q5WKY6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: November 23, 2004
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi