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Protein

Uronate isomerase

Gene

uxaC

Organism
Bacillus clausii (strain KSM-K16)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciBCLA66692:GHMP-1042-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:ABC0995
OrganismiBacillus clausii (strain KSM-K16)
Taxonomic identifieri66692 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001168 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 472472Uronate isomerasePRO_0000172760Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi66692.ABC0995.

Structurei

3D structure databases

ProteinModelPortaliQ5WJC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5WJC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISTGKAFIH ENFMLQNKTA ETLYHTYAKT LPIIDYHCHV PPQEIAENRQ
60 70 80 90 100
FNNISEIWLH GDHYKWRAMR AVGVEETFIT GDGDDKEKFL KWAETVPYTM
110 120 130 140 150
GNPLYHWTHL ELKRYFGIDE LLSSETAEAI WSATKEQLAA PERSVQGIIK
160 170 180 190 200
ESNVKVICTT DDPSDHLEAH QQIRKEGACQ AAVYPAFRPD KALVASAPSF
210 220 230 240 250
VPYLETLGAA AEVDISSLRS LLEALEKRAT FFAEEGCVLS DHGLRTLPFV
260 270 280 290 300
DTTEKEAEAA FQKALNQETL TPQEEEKYQT YVLLFLARLY NKLGWTMQFH
310 320 330 340 350
LGALRNNNSR MVEQVGPDSG FDSMADDRFA ESLNRFLNEL ERTNELPKTI
360 370 380 390 400
LYTLNPIFNE VIATTIGNFQ GGGIPGKIQF GSGWWFNDTK DGMEKQMTDL
410 420 430 440 450
ANNGLLSLFV GMLTDSRSFL SYTRHEYFRR ILCNRIGEWV ERGEWPADEK
460 470
WLGKVVEDIS YYNAKRYFAF PK
Length:472
Mass (Da):53,983
Last modified:November 23, 2004 - v1
Checksum:i8274B351590594E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006627 Genomic DNA. Translation: BAD63534.1.
RefSeqiWP_011245850.1. NC_006582.1.

Genome annotation databases

EnsemblBacteriaiBAD63534; BAD63534; ABC0995.
KEGGibcl:ABC0995.
PATRICi18921344. VBIBacCla58185_1060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006627 Genomic DNA. Translation: BAD63534.1.
RefSeqiWP_011245850.1. NC_006582.1.

3D structure databases

ProteinModelPortaliQ5WJC1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi66692.ABC0995.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD63534; BAD63534; ABC0995.
KEGGibcl:ABC0995.
PATRICi18921344. VBIBacCla58185_1060.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciBCLA66692:GHMP-1042-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_BACSK
AccessioniPrimary (citable) accession number: Q5WJC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: November 23, 2004
Last modified: September 7, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.