Reviewed, UniProtKB/Swiss-Prot Q5WHD6 (SYGA_BACSK)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	ABC1684

Organism

Bacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]

Taxonomic identifier

66692 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	295 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00254
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 295	295	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000047399

Sequences

	Sequence		Length	Mass (Da)
	Q5WHD6-1 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: C56F12984B778953	FASTA	295	34,156
	10 20 30 40 50 60 MNVQTMILTL QSFWAKQNCI ILNAYDTEKG AGTMSPHTLL RTIGPEPWNV AYVEPSRRPA 70 80 90 100 110 120 DGRYGENPNR LYQHHQFQVI MKPSPLNIQE LYLDSLRALG IDPLKHDIRF VEDNWENPTL 130 140 150 160 170 180 GCAGLGWEVW LDGMEITQFT YFQQVGGMEA NPVSAEITYG LERLATYIQD KENVFDLEWV 190 200 210 220 230 240 EGFTYGDIFL QPEYEHSTYT FEVSNVDMLF DLFSTYEKEA ERALARDLVF PAYDYILKCS 250 260 270 280 290 HSFNLLDARG AISVTERTGY IARVRTLARK AARKYYEERE KLGFPMLKKE DAHDE

References

[1]	"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16." Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006627 Genomic DNA. Translation: BAD64219.1.
RefSeq	YP_175180.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WHD6.
Genome annotation databases
GeneID	3204538.
GenomeReviews	Gene locus ABC1684 in contig AP006627_GR.
KEGG	bcl:ABC1684.
NMPDR	fig|66692.3.peg.67.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5WHD6.
OMA	CRRPTDG.
Enzyme and pathway databases
BioCyc	BCLA66692:ABC1684-MON.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_BACSK

Accession

Primary (citable) accession number: Q5WHD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 23, 2004
Last modified:	November 3, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)