Q5WH73 (MSRB_BACSK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	ABC1747

Organism

Bacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]

Taxonomic identifier

66692 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 144	144	Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400		PRO_0000140261
Sites
	Active site	117	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5WH73 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: F674D6428400F65C	FASTA	144	16,386
	10 20 30 40 50 60 MTKPQKDELK KKLTPIQYFV TQENGTEPPF QNEYYETEEE GIYVDVVSGK PLFSSKDKYD 70 80 90 100 110 120 AGCGWPSFTK PIDEAEIIEK EDRSHFMVRT EVRSKNADSH LGHVFPDGPG PNGLRYCINS 130 140 AALRFIPKAK LKEAGYGAYE KLFD

References

[1]

"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16." Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KSM-K16.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006627 Genomic DNA. Translation: BAD64282.1.
RefSeq	YP_175243.1. NC_006582.1.
3D structure databases
ProteinModelPortal	Q5WH73.
SMR	Q5WH73. Positions 6-144.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WH73.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000049580; EBBACP00000048341; EBBACG00000049571.
GeneID	3201152.
GenomeReviews	Gene locus ABC1747 in contig AP006627_GR.
KEGG	bcl:ABC1747.
NMPDR	fig|66692.3.peg.1706.
PATRIC	18922986. VBIBacCla58185_1856.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0229.
GeneTree	EBGT00050000000580.
HOGENOM	HBG715255.
OMA	FTDGPVD.
ProtClustDB	PRK00222.
Enzyme and pathway databases
BioCyc	BCLA66692:ABC1747-MONOMER.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_BACSK

Accession

Primary (citable) accession number: Q5WH73

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program