Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q5WH44 (UPPP1_BACSK)

Last modified November 3, 2009. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Undecaprenyl-diphosphatase 1
    EC=3.6.1.27
Alternative name(s):
    Undecaprenyl pyrophosphate phosphatase 1
    Bacitracin resistance protein 1
Gene names
Name: uppP1
Ordered Locus Names: ABC1776
OrganismBacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]
Taxonomic identifier66692 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillus

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity.

Catalytic activity

Undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate. HAMAP MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. HAMAP MF_01006

Sequence similarities

Belongs to the uppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 277277Undecaprenyl-diphosphatase 1 HAMAP MF_01006
PRO_0000151107

Regions

Transmembrane1 – 2121 Potential
Transmembrane39 – 5820 Potential
Transmembrane85 – 10521 Potential
Transmembrane113 – 13321 Potential
Transmembrane147 – 16721 Potential
Transmembrane191 – 21121 Potential
Transmembrane226 – 24621 Potential
Transmembrane251 – 27121 Potential

Sequences

Sequence LengthMass (Da)Tools
Q5WH44-1 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 5E8DF896606E9EF4

FASTA27730,396
        10         20         30         40         50         60 
MSLLEAVILG LVQGITEFLP ISSSAHLILV QALFGMTFAG FSFEILLHLA SVLAVILYYR 

        70         80         90        100        110        120 
HDLIEIIRGF FAYFTKRTPQ NKAMFWFAIY LVVATGITGV AGILFEDYIS ETFKAPIFIA 

       130        140        150        160        170        180 
LALAVTGLFL IIIERFVRHG NRTEKEMTIW DSIIVGLGQC LALIPGLSRS GTTLIVGMFA 

       190        200        210        220        230        240 
GLTKETAVRF SFLLSIPVIL GSSVLAIDDL ISGDLLASTG LFELAASFVV TFIASWLGIV 

       250        260        270 
FFLNLVRKSK LVYFAVYCFI VAILVFIFQD ALGHADI 

« Hide

References

[1]"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AP006627 Genomic DNA. Translation: BAD64311.1.
RefSeqYP_175272.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ5WH44.

Genome annotation databases

GeneID3201173.
GenomeReviewsGene locus ABC1776 in contig AP006627_GR.
KEGGbcl:ABC1776.
NMPDRfig|66692.3.peg.1724.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ5WH44.
OMAILMLEFN.

Enzyme and pathway databases

BioCycBCLA66692:ABC1776-MON.

Family and domain databases

HAMAPMF_01006.
[Tree]
InterProIPR003824. Bacitracin-R_BacA.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP1_BACSK
AccessionPrimary (citable) accession number: Q5WH44
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: November 23, 2004
Last modified: November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents