Reviewed, UniProtKB/Swiss-Prot Q5WGU8 (KCY_BACSK)

Names and origin

Protein names

Recommended name:
    Cytidylate kinase
      Short name=CK
    EC=2.7.4.14
Alternative name(s):
    Cytidine monophosphate kinase
      Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	ABC1872

Organism

Bacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]

Taxonomic identifier

66692 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	225 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 225	225	Cytidylate kinase HAMAP MF_00238		PRO_0000131879
Regions
	Nucleotide binding	11 – 19	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5WGU8-1 [UniParc]. Last modified February 15, 2005. Version 2. Checksum: 269CCCE04FB4115F	FASTA	225	24,399
	10 20 30 40 50 60 MAKGFNVAID GPAGAGKSTV AKKTAEKLGF LYIDTGAMYR AITFAALAEG IDLHDGKALG 70 80 90 100 110 120 KLLEKSELRL ESSNEGTAVF WNGADITAAI RTNEVNSNVS LVASHREVRE GMTAMQQELA 130 140 150 160 170 180 KSKNAVLDGR DIGTHVLPDA NVKVFLTASV EERARRRHLE QLEKGLPSDF EQLKKDIAKR 190 200 210 220 DELDSTRAIA PLKQAADAQV VDTTSMGIDE VVETILDLVK EHSRQ

References

[1]	"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16." Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006627 Genomic DNA. Translation: BAD64407.1. Different initiation.
RefSeq	YP_175368.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WGU8.
Genome annotation databases
GeneID	3203831.
GenomeReviews	Gene locus ABC1872 in contig AP006627_GR.
KEGG	bcl:ABC1872.
NMPDR	fig|66692.3.peg.26.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5WGU8.
Enzyme and pathway databases
BioCyc	BCLA66692:ABC1872-MON.
Family and domain databases
HAMAP	MF_00238. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kin_d. [Graphical view]
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
ProDom	PD000657. Adenylate_kin. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00017. cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BACSK

Accession

Primary (citable) accession number: Q5WGU8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	September 1, 2009
This is version 28 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)