Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q5WGR7 (AROA_BACSK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Synonyms:aroE
Ordered Locus Names:ABC1903
OrganismBacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]
Taxonomic identifier66692 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4304303-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_0000088226

Sequences

Sequence LengthMass (Da)Tools
Q5WGR7 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 5EFE78F344053221

FASTA43044,875
        10         20         30         40         50         60 
MDETIKLLNK AESGLSGTIV VPGDKSISHR AVMFGAMANG TTNVSGFLPG DDCLSTIACF 

        70         80         90        100        110        120 
RQMGVAIEQE GDKVTVEGKG LDGLKEPNGV LDVGNSGTTI RLLLGVLSGR PFHSVVVGDD 

       130        140        150        160        170        180 
SIGKRPMARV TAPLRQMGAQ IDGRETGNKT PLSIRGGQTK AIEYTMPVAS AQVKSALLLA 

       190        200        210        220        230        240 
GLQAEGETSV TEPQTTRDHT ERMLHAFGVK VTTAGKTISI QGGQSLQAAD VVVPGDISSA 

       250        260        270        280        290        300 
AFFLVAGCIV PGSRVHLKNV GLNPTRAGIL EVLKRSGAKL SIDEQVTTGG EPRGDMTIST 

       310        320        330        340        350        360 
SELSPFVIEG EEVPTLIDEI PVLAVLATQI SGTTIIRDAE ELKVKETNRI DTVVGELAKL 

       370        380        390        400        410        420 
GADIEATDDG MIIRGGKPLT GGKVDSHGDH RIGMALVIAS LCANGPVELA NIGAISVSYP 

       430 
QFFEHLQSLQ

« Hide

References

[1]"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KSM-K16.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006627 Genomic DNA. Translation: BAD64438.1.
RefSeqYP_175399.1. NC_006582.1.

3D structure databases

ProteinModelPortalQ5WGR7.
SMRQ5WGR7. Positions 11-429.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5WGR7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000047664; EBBACP00000046425; EBBACG00000047655.
GeneID3201725.
GenomeReviewsGene locus ABC1903 in contig AP006627_GR.
KEGGbcl:ABC1903.
NMPDRfig|66692.3.peg.1947.
PATRIC18923326. VBIBacCla58185_2026.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
GeneTreeEBGT00050000001036.
HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycBCLA66692:ABC1903-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_BACSK
AccessionPrimary (citable) accession number: Q5WGR7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: November 23, 2004
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents