ID   DAPB_BACSK              Reviewed;         264 AA.
AC   Q5WGQ4;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   16-JUN-2009, entry version 33.
DE   RecName: Full=Dihydrodipicolinate reductase;
DE            Short=DHPR;
DE            EC=1.3.1.26;
GN   Name=dapB; OrderedLocusNames=ABC1916;
OS   Bacillus clausii (strain KSM-K16).
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=66692;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y.,
RA   Kawai S., Ito S., Horikoshi K.;
RT   "The complete genome sequence of the alkaliphilic Bacillus clausii
RT   KSM-K16.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: 2,3,4,5-tetrahydrodipicolinate + NAD(P)(+) =
CC       2,3-dihydrodipicolinate + NAD(P)H.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; tetrahydrodipicolinate from L-aspartate: step 4/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the dihydrodipicolinate reductase family.
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DR   EMBL; AP006627; BAD64451.1; -; Genomic_DNA.
DR   RefSeq; YP_175412.1; -.
DR   GeneID; 3203886; -.
DR   GenomeReviews; AP006627_GR; ABC1916.
DR   KEGG; bcl:ABC1916; -.
DR   NMPDR; fig|66692.3.peg.1960; -.
DR   HOGENOM; Q5WGQ4; -.
DR   OMA; Q5WGQ4; VLMMKFA.
DR   BioCyc; BCLA66692:ABC1916-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0008839; F:dihydrodipicolinate reductase activity; IEA:HAMAP.
DR   GO; GO:0019877; P:diaminopimelate biosynthetic process; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00102; -; 1.
DR   InterPro; IPR000846; DapB.
DR   InterPro; IPR011770; DapB_bac/pln.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR20836; DapB_bac/pln; 1.
DR   Pfam; PF05173; DapB_C; 1.
DR   Pfam; PF01113; DapB_N; 1.
DR   ProDom; PD004105; DapB; 1.
DR   TIGRFAMs; TIGR00036; dapB; 1.
DR   PROSITE; PS01298; DAPB; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm;
KW   Diaminopimelate biosynthesis; Lysine biosynthesis; NADP;
KW   Oxidoreductase.
FT   CHAIN         1    264       Dihydrodipicolinate reductase.
FT                                /FTId=PRO_0000228323.
SQ   SEQUENCE   264 AA;  29013 MW;  7E7A4A904899ADFF CRC64;
     MTRIVIAGPR GNMGQEAVKL CLREESFELV AVVDSKNDGK QLKGLQEFQQ GDVPVYTDMA
     RCFAEHEPDV LIDLTAPAFG RKHMEVAFEH GVRPVVGTTG FSDEDIRDLT KLAEAKELGA
     IIAPNFAIGA ILMMKFAQTA ARYMNDVEII EQHHDRKLDA PSGTAVKTAQ LIAEVRAPKK
     QGHEQEREEM AGARGADFDG MKIHSVRLPG RVAHQEVLFG GVGQTLSIRH DSLNRESFMP
     GVKLAVEQVV KLSTLVYGLE NLID
//