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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Bacillus clausii (strain KSM-K16)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Enzyme and pathway databases

BioCyciBCLA66692:G1G25-2638-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Ordered Locus Names:ABC2495
OrganismiBacillus clausii (strain KSM-K16)
Taxonomic identifieri66692 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001168 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001225421 – 367AminomethyltransferaseAdd BLAST367

Proteomic databases

PRIDEiQ5WF30

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi66692.ABC2495

Structurei

3D structure databases

ProteinModelPortaliQ5WF30
SMRiQ5WF30
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D43 Bacteria
COG0404 LUCA
HOGENOMiHOG000239381
KOiK00605
OMAiMPVQYPA
OrthoDBiPOG091H04FV

Family and domain databases

Gene3Di3.30.1360.120, 2 hits
HAMAPiMF_00259 GcvT, 1 hit
InterProiView protein in InterPro
IPR006223 GCS_T
IPR022903 GCS_T_bac
IPR028896 GCST/YgfZ/DmdA
IPR013977 GCV_T_C
IPR006222 GCV_T_N
IPR029043 GcvT/YgfZ_C
IPR027266 TrmE/GcvT_dom1
PfamiView protein in Pfam
PF01571 GCV_T, 1 hit
PF08669 GCV_T_C, 1 hit
PIRSFiPIRSF006487 GcvT, 1 hit
SUPFAMiSSF101790 SSF101790, 1 hit
TIGRFAMsiTIGR00528 gcvT, 1 hit

Sequencei

Sequence statusi: Complete.

Q5WF30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKLLRTPL YELYDQAGAK TVDFGGWELP VSFSGIKKEH HAVRNAAGLF
60 70 80 90 100
DVSHMGELLV EGPDALNNLQ ALVTNDLSKL QDNQAQYNAM CTESGGTVDD
110 120 130 140 150
LIVYRRNENA YLLVLNAANI QSDIEWIRAH VSGQVTLTDI SNETALLAVQ
160 170 180 190 200
GPKALAVLQT LTDEPLSEIR PFRFKENVMF AAIPVLASRT GYTGEDGFEL
210 220 230 240 250
YVKAGDAAEL WRAILAAGEP FGLLPCGLGA RDTLRFEARL PLYGQELTKD
260 270 280 290 300
ISPIEAGIGF AVKTDKQAAF IGQQALKKQK EQGPSRKLVG IEMVDRGIPR
310 320 330 340 350
TGYRVFYQGQ DVGFVTSGTQ SPTLGKNVGL VLAKADAAAI DTELEVEVRG
360
KRLRARVVKT PFYKRTK
Length:367
Mass (Da):40,129
Last modified:November 23, 2004 - v1
Checksum:i6BFF261BDD9F3ED8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006627 Genomic DNA Translation: BAD65030.1
RefSeqiWP_011247338.1, NC_006582.1

Genome annotation databases

EnsemblBacteriaiBAD65030; BAD65030; ABC2495
GeneIDi34043309
KEGGibcl:ABC2495

Similar proteinsi

Entry informationi

Entry nameiGCST_BACSK
AccessioniPrimary (citable) accession number: Q5WF30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: November 23, 2004
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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