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Reviewed, UniProtKB/Swiss-Prot Q5WEM4 (NTPA_BACSK)

Last modified July 22, 2008. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase
Gene names
Ordered Locus Names: ABC2651
OrganismBacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]
Taxonomic identifier66692 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillus

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.

Catalytic activity

NTP + H(2)O = NDP + phosphate.

Cofactor

Divalent cations By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the HAM1 NTPase family.

Ontologies

Keywords

   Molecular functionHydrolase
   Technical termComplete proteome

Gene Ontology (GO)

   Molecular functionnucleoside-triphosphatase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Nucleoside-triphosphatase
PRO_0000178128

Sequences

Sequence LengthMass (Da)Tools
Q5WEM4-1 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 03FCDFD235EF0D6B

FASTA19821,585
        10         20         30         40         50         60 
MNELVVATKN KGKLADFQTL FTDRYIVKSL YDYPEVPEII EDGDTFHENA AKKAETLAAY 

        70         80         90        100        110        120 
LQKLVIADDS GLLIDALGGK PGVYSARYAG EPKNDQANID KVLSELDGVP TQKRTARFFC 

       130        140        150        160        170        180 
VIALAEPGKE TIFAEGACEG RITEKPTGSN GFGYDPIFFV PSHGQTMAEL SAGTKNQLSH 

       190 
RARALTALKE TIEGVWPK 

« Hide

References

[1]"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AP006627 Genomic DNA. Translation: BAD65186.1.
RefSeqYP_176147.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3204761.
GenomeReviewsGene locus ABC2651 in contig AP006627_GR.
KEGGbcl:ABC2651.
NMPDRfig|66692.3.peg.2974.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ5WEM4.

Enzyme and pathway databases

BioCycBCLA66692:ABC2651-MON.

Family and domain databases

HAMAPMF_01405.
[Tree]
InterProIPR002637. Ham1p_like.
[Graphical view]
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. Ham1p_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNTPA_BACSK
AccessionPrimary (citable) accession number: Q5WEM4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: November 23, 2004
Last modified: July 22, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents