Q5WEL9 (MURI_BACSK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	ABC2656

Organism

Bacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]

Taxonomic identifier

66692 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Glutamate racemase HAMAP MF_00258		PRO_1000047544

Sequences

	Sequence		Length	Mass (Da)
	Q5WEL9 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 12A466EF9A1E72D8	FASTA	276	29,714
	10 20 30 40 50 60 MSRPIGIIDS GIGGLTVASE IMRQLPKEPI VYIGDSARCP YGPRPVEEVR AFTWQMIGRL 70 80 90 100 110 120 LHEDVKMIVI ACNTATAVVL EEARAQLDIP VVGVIRPGAI SAIQVSENRH VAVIGTIGTI 130 140 150 160 170 180 ASNAYTMALH SIDENVTVES LACPLFVPLV EQGTIKGPEA EAVVRESLAP LQGAGFDTLI 190 200 210 220 230 240 LGCTHYPLLK PVIEACLPSV TVISSGEETA REVSSLLFYH SMNEQHQAKA THRFYTTGEA 250 260 270 NQFKQLAASW LNIHTDSVAS IHLDGPLPVQ ATMKSK

References

[1]

"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16." Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KSM-K16.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006627 Genomic DNA. Translation: BAD65191.1.
RefSeq	YP_176152.1. NC_006582.1.
3D structure databases
HSSP	HSSP built from PDB template 1ZUW based on UniProtKB P94556.
ProteinModelPortal	Q5WEL9.
SMR	Q5WEL9. Positions 1-264.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WEL9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000048983; EBBACP00000047744; EBBACG00000048974.
GeneID	3202841.
GenomeReviews	Gene locus ABC2656 in contig AP006627_GR.
KEGG	bcl:ABC2656.
NMPDR	fig|66692.3.peg.2979.
PATRIC	18924964. VBIBacCla58185_2832.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0796.
GeneTree	EBGT00050000002346.
HOGENOM	HBG645102.
OMA	PQEDTIY.
Enzyme and pathway databases
BioCyc	BCLA66692:ABC2656-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BACSK

Accession

Primary (citable) accession number: Q5WEL9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program