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Q5WED5 (ACKA_BACSK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:ABC2740
OrganismBacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]
Taxonomic identifier66692 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Acetate kinase HAMAP MF_00020
PRO_0000107533

Sequences

Sequence LengthMass (Da)Tools
Q5WED5 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: F8BFCE8D4665F924

FASTA39542,575
        10         20         30         40         50         60 
MAKIIAINAG SSSLKFQLLA MPEETVIAKG LVERIGLKKS IFTIEANGQQ HELTEDIPDH 

        70         80         90        100        110        120 
AAAVKLLLKD LTGRGIIASL EEIEGIGHRV VHGGEKFNDS VVITDEVLQG IEEVSELAPL 

       130        140        150        160        170        180 
HNPANITGIK AFKEVLPNVP AVAVFDTAFH QTMPESAFLY SLPYEYYEKY GIRKYGFHGT 

       190        200        210        220        230        240 
SHKYVTHRAA ELMETPIEEL RILSCHLGNG ASIAAVKGGK SIDTSMGFTP LAGVTMGTRS 

       250        260        270        280        290        300 
GNIDPALIPY IMEKTGQSVE EVVATLNKKS GLLGITGFSS DLRDIEAAAK EGDERAQVAL 

       310        320        330        340        350        360 
DVFASRIHKY VGSYAARMGG LDAIVFTAGI GENSATIRER VLKGLSFMGV DVDLEKNNVR 

       370        380        390 
GKEAFIEKAG APVKIIVIPT NEEVMIARDT VRLTS

« Hide

References

[1]"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KSM-K16.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006627 Genomic DNA. Translation: BAD65275.1.
RefSeqYP_176236.1. NC_006582.1.

3D structure databases

ProteinModelPortalQ5WED5.
SMRQ5WED5. Positions 3-394.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5WED5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000049660; EBBACP00000048421; EBBACG00000049651.
GeneID3203528.
GenomeReviewsGene locus ABC2740 in contig AP006627_GR.
KEGGbcl:ABC2740.
NMPDRfig|66692.3.peg.2596.
PATRIC18925138. VBIBacCla58185_2919.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
GeneTreeEBGT00050000000769.
HOGENOMHBG285863.
OMALIDMTNE.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycBCLA66692:ABC2740-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BACSK
AccessionPrimary (citable) accession number: Q5WED5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: November 23, 2004
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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