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Protein

L-cystine uptake protein TcyP

Gene

ABC2897

Organism
Bacillus clausii (strain KSM-K16)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Mediates uptake of L-cystine, the oxidized form of L-cysteine.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciBCLA66692:GHMP-2978-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
L-cystine uptake protein TcyP
Alternative name(s):
Transporter of cystine TcyP
Gene namesi
Ordered Locus Names:ABC2897
OrganismiBacillus clausii (strain KSM-K16)
Taxonomic identifieri66692 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001168 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalSequence analysisAdd
BLAST
Transmembranei34 – 5421HelicalSequence analysisAdd
BLAST
Transmembranei73 – 9321HelicalSequence analysisAdd
BLAST
Transmembranei105 – 12521HelicalSequence analysisAdd
BLAST
Transmembranei184 – 20421HelicalSequence analysisAdd
BLAST
Transmembranei224 – 24623HelicalSequence analysisAdd
BLAST
Transmembranei263 – 28321HelicalSequence analysisAdd
BLAST
Transmembranei338 – 35821HelicalSequence analysisAdd
BLAST
Transmembranei370 – 39021HelicalSequence analysisAdd
BLAST
Transmembranei394 – 41421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 465465L-cystine uptake protein TcyPPRO_0000279739Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi66692.ABC2897.

Structurei

3D structure databases

ProteinModelPortaliQ5WDX9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1823. LUCA.
HOGENOMiHOG000208777.
KOiK06956.
OMAiLAIMTKT.
OrthoDBiEOG6HQSKK.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR001991. Na-dicarboxylate_symporter.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5WDX9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLFLTLLII AIVLAVAGLL FYMQKKHVSF SIRVLLALGA GVVYGLLLQF
60 70 80 90 100
FFAPDSSVIQ QSMDWVNILG TGYVRFLQMI VMPLIFISIL SAFTRMTLTK
110 120 130 140 150
NLGKISALIL GTLIATTAIA AAIGITASSV FQLEAIDIPA GEAELSHGDA
160 170 180 190 200
LEESYAGMEA ATLPQQIVEL IPANPFLDLT GERPTSAIGV VIFSAFLGVA
210 220 230 240 250
YLGVRRKQPE AADTFKGIVN ALYAIIMRVV TLILRLTPYG VLAIMTRTVA
260 270 280 290 300
TSDLQAISTL GTFVLASYAA LIVMFVIHLI ILAATGLSPI TYVKKAFPVL
310 320 330 340 350
AFAFTSRTSA GALPMNIQTQ KKLGVPEGIA NFAGSFGLSI GQNGCAGIYP
360 370 380 390 400
AMLAVMIAPT VGQNPLEPTF ILLLIVVIAI SSFGVAGVGG GATFAAILVL
410 420 430 440 450
SALDFPIALA GLLISIEPLI DMGRTALNVS GSMVSGIFTS KVTGSLDKEV
460
FSDPNEQLDT QDMQG
Length:465
Mass (Da):48,930
Last modified:November 23, 2004 - v1
Checksum:iCDD4A8F64954FD53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006627 Genomic DNA. Translation: BAD65431.1.
RefSeqiWP_011247739.1. NC_006582.1.

Genome annotation databases

EnsemblBacteriaiBAD65431; BAD65431; ABC2897.
KEGGibcl:ABC2897.
PATRICi18925484. VBIBacCla58185_3092.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006627 Genomic DNA. Translation: BAD65431.1.
RefSeqiWP_011247739.1. NC_006582.1.

3D structure databases

ProteinModelPortaliQ5WDX9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi66692.ABC2897.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD65431; BAD65431; ABC2897.
KEGGibcl:ABC2897.
PATRICi18925484. VBIBacCla58185_3092.

Phylogenomic databases

eggNOGiCOG1823. LUCA.
HOGENOMiHOG000208777.
KOiK06956.
OMAiLAIMTKT.
OrthoDBiEOG6HQSKK.

Enzyme and pathway databases

BioCyciBCLA66692:GHMP-2978-MONOMER.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR001991. Na-dicarboxylate_symporter.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."
    Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KSM-K16.

Entry informationi

Entry nameiTCYP_BACSK
AccessioniPrimary (citable) accession number: Q5WDX9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: November 23, 2004
Last modified: July 6, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.