Q5WB97 (FABZ_BACSK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	ABC3832

Organism

Bacillus clausii (strain KSM-K16) [Complete proteome] [HAMAP]

Taxonomic identifier

66692 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	142 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 142	142	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_0000091641
Sites
	Active site	48	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5WB97 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 0B39EF211C9A53FF	FASTA	142	15,423
	10 20 30 40 50 60 MLTVEEIKAL IPHRYPFLLV DKVIELEAGK RAVGIKNVTI NEEFFNGHFP HYAVMPGVLI 70 80 90 100 110 120 VEALAQVSGV AIAKAQEGTN KVGLFAAIDG CKFKRPVRPG DQLRLETEIT RVKGPIAKAT 130 140 GTAYVDGEVA AQAEMTFAFK DV

References

[1]

"The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16." Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KSM-K16.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006627 Genomic DNA. Translation: BAD66363.1.
RefSeq	YP_177324.1. NC_006582.1.
3D structure databases
ProteinModelPortal	Q5WB97.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WB97.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000047470; EBBACP00000046231; EBBACG00000047461.
GeneID	3201370.
GenomeReviews	Gene locus ABC3832 in contig AP006627_GR.
KEGG	bcl:ABC3832.
NMPDR	fig|66692.3.peg.3807.
PATRIC	18927468. VBIBacCla58185_4082.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0764.
GeneTree	EBGT00050000002061.
HOGENOM	HBG433282.
OMA	KKQVTPG.
Enzyme and pathway databases
BioCyc	BCLA66692:ABC3832-MONOMER.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_BACSK

Accession

Primary (citable) accession number: Q5WB97

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2005
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program