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Q5W9H1

- Q5W9H1_HUMAN

UniProt

Q5W9H1 - Q5W9H1_HUMAN

Protein
Submitted name:

KIAA0142 splice variant 1

Gene

KIAA0142

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. Rho guanyl-nucleotide exchange factor activity Source: InterPro

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    KIAA0142 splice variant 1Imported
    Gene namesi
    Name:KIAA0142Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5W9H1.

    Expressioni

    Gene expression databases

    BgeeiQ5W9H1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5W9H1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PH domain.UniRule annotation
    Contains DH (DBL-homology) domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000231381.
    HOVERGENiHBG050569.

    Family and domain databases

    Gene3Di1.10.418.10. 1 hit.
    1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    InterProiIPR001715. CH-domain.
    IPR000219. DH-domain.
    IPR001331. GDS_CDC24_CS.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00307. CH. 1 hit.
    PF00169. PH. 1 hit.
    PF00621. RhoGEF. 1 hit.
    PF07653. SH3_2. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00033. CH. 1 hit.
    SM00233. PH. 1 hit.
    SM00325. RhoGEF. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF47576. SSF47576. 1 hit.
    SSF48065. SSF48065. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEiPS50021. CH. 1 hit.
    PS00741. DH_1. 1 hit.
    PS50010. DH_2. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q5W9H1-1 [UniParc]FASTAAdd to Basket

    « Hide

    IPPSKPLRGS SLWGCWSRPK KTISDPEGFL QASLKDGVVL CRLLERLLPG    50
    TIEKVYPEPR SESECLSNIR EFLRGCGASL RLETFDANDL YQGQNFNKVL 100
    SSLVTLNKVT ADIGLGSDSV CARPSSHRIK SFDSLGSQSL HTRTSKLFQG 150
    QYRSLDMTDN SNNQLVVRAK FNFQQTNEDE LSFSKGDVIH VTRVEEGGWW 200
    EGTLNGRTGW FPSNYVREVK ASEKPVSPKS GTLKSPPKGF DTTAINKSYY 250
    NVVLQNILET ENEYSKELQT VLSTYLRPLQ TSEKLSSANI SYLMGNLEEI 300
    CSFQQMLVQS LEECTKLPEA QQRVGGCFLN LMPQMKTLYL TYCANHPSAV 350
    NVLTEHSEEL GEFMETKGAS SPGILVLTTG LSKPFMRLDK YPTLLKELER 400
    HMEDYHTDRQ DIQKSMAAFK NLSAQCQEVR KRKELELQIL TEAIRNWEGD 450
    DIKTLGNVTY MSQVLIQCAG SEEKNERYLL LFPNVLLMLS ASPRMSGFIY 500
    QGKLPTTGMT ITKLEDSENH RNAFEISGSM IERILVSCNN QQDLQEWVEH 550
    LQKQTKVTSV GNPTIKPHSV PSHTLPSHPV TPSSKHADSK PAPLTPAYHT 600
    LPHPSHHGTP HTTINWGPLE PPKTPKPWSL SCLRPAPPLR PSAALCYKED 650
    LSKSPKTMKK LLPKRKPERK PSMRSSRPGK AQLLWKKMLR F 691
    Length:691
    Mass (Da):77,790
    Last modified:December 7, 2004 - v1
    Checksum:i79570CF1CA88AFEE
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB177848 mRNA. Translation: BAD66826.1.
    UniGeneiHs.508738.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB177848 mRNA. Translation: BAD66826.1 .
    UniGenei Hs.508738.

    3D structure databases

    ProteinModelPortali Q5W9H1.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5W9H1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    HUGEi Search...

    Phylogenomic databases

    HOGENOMi HOG000231381.
    HOVERGENi HBG050569.

    Miscellaneous databases

    ChiTaRSi ARHGEF7. human.

    Gene expression databases

    Bgeei Q5W9H1.

    Family and domain databases

    Gene3Di 1.10.418.10. 1 hit.
    1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    InterProi IPR001715. CH-domain.
    IPR000219. DH-domain.
    IPR001331. GDS_CDC24_CS.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00307. CH. 1 hit.
    PF00169. PH. 1 hit.
    PF00621. RhoGEF. 1 hit.
    PF07653. SH3_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00033. CH. 1 hit.
    SM00233. PH. 1 hit.
    SM00325. RhoGEF. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47576. SSF47576. 1 hit.
    SSF48065. SSF48065. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEi PS50021. CH. 1 hit.
    PS00741. DH_1. 1 hit.
    PS50010. DH_2. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Alternative splice variants encoding unstable protein domains exist in the human brain."
      Homma K., Kikuno R.F., Nagase T., Ohara O., Nishikawa K.
      J. Mol. Biol. 343:1207-1220(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ5W9H1_HUMAN
    AccessioniPrimary (citable) accession number: Q5W9H1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 7, 2004
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.