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Q5W9H1

- Q5W9H1_HUMAN

UniProt

Q5W9H1 - Q5W9H1_HUMAN

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Protein
Submitted name:

KIAA0142 splice variant 1

Gene
KIAA0142
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
KIAA0142 splice variant 1Imported
Gene namesi
Name:KIAA0142Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ5W9H1.

Expressioni

Gene expression databases

BgeeiQ5W9H1.

Structurei

3D structure databases

ProteinModelPortaliQ5W9H1.

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation
Contains DH (DBL-homology) domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000231381.
HOVERGENiHBG050569.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR001715. CH-domain.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00307. CH. 1 hit.
PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00033. CH. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
SSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50021. CH. 1 hit.
PS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5W9H1-1 [UniParc]FASTAAdd to Basket

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IPPSKPLRGS SLWGCWSRPK KTISDPEGFL QASLKDGVVL CRLLERLLPG    50
TIEKVYPEPR SESECLSNIR EFLRGCGASL RLETFDANDL YQGQNFNKVL 100
SSLVTLNKVT ADIGLGSDSV CARPSSHRIK SFDSLGSQSL HTRTSKLFQG 150
QYRSLDMTDN SNNQLVVRAK FNFQQTNEDE LSFSKGDVIH VTRVEEGGWW 200
EGTLNGRTGW FPSNYVREVK ASEKPVSPKS GTLKSPPKGF DTTAINKSYY 250
NVVLQNILET ENEYSKELQT VLSTYLRPLQ TSEKLSSANI SYLMGNLEEI 300
CSFQQMLVQS LEECTKLPEA QQRVGGCFLN LMPQMKTLYL TYCANHPSAV 350
NVLTEHSEEL GEFMETKGAS SPGILVLTTG LSKPFMRLDK YPTLLKELER 400
HMEDYHTDRQ DIQKSMAAFK NLSAQCQEVR KRKELELQIL TEAIRNWEGD 450
DIKTLGNVTY MSQVLIQCAG SEEKNERYLL LFPNVLLMLS ASPRMSGFIY 500
QGKLPTTGMT ITKLEDSENH RNAFEISGSM IERILVSCNN QQDLQEWVEH 550
LQKQTKVTSV GNPTIKPHSV PSHTLPSHPV TPSSKHADSK PAPLTPAYHT 600
LPHPSHHGTP HTTINWGPLE PPKTPKPWSL SCLRPAPPLR PSAALCYKED 650
LSKSPKTMKK LLPKRKPERK PSMRSSRPGK AQLLWKKMLR F 691
Length:691
Mass (Da):77,790
Last modified:December 7, 2004 - v1
Checksum:i79570CF1CA88AFEE
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB177848 mRNA. Translation: BAD66826.1.
UniGeneiHs.508738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB177848 mRNA. Translation: BAD66826.1 .
UniGenei Hs.508738.

3D structure databases

ProteinModelPortali Q5W9H1.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q5W9H1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

HUGEi Search...

Phylogenomic databases

HOGENOMi HOG000231381.
HOVERGENi HBG050569.

Miscellaneous databases

ChiTaRSi ARHGEF7. human.

Gene expression databases

Bgeei Q5W9H1.

Family and domain databases

Gene3Di 1.10.418.10. 1 hit.
1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR001715. CH-domain.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00307. CH. 1 hit.
PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00033. CH. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF47576. SSF47576. 1 hit.
SSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEi PS50021. CH. 1 hit.
PS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Alternative splice variants encoding unstable protein domains exist in the human brain."
    Homma K., Kikuno R.F., Nagase T., Ohara O., Nishikawa K.
    J. Mol. Biol. 343:1207-1220(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ5W9H1_HUMAN
AccessioniPrimary (citable) accession number: Q5W9H1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 3, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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