Q5W188 (CST9P_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative cystatin-9-like protein CST9LP1

Alternative name(s):
Cystatin-9-like pseudogene 1

Gene names

Name:

CST9LP1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Uncertain

General annotation (Comments)

Subcellular location	Secreted Potential.
Sequence similarities	Belongs to the cystatin family.
Caution	Could be the product of a pseudogene.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Molecular function	Protease inhibitor Thiol protease inhibitor
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cysteine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Chain	29 – 147	119	Putative cystatin-9-like protein CST9LP1		PRO_0000285800
Amino acid modifications
	Glycosylation	117	1	N-linked (GlcNAc...) Potential
	Glycosylation	139	1	N-linked (GlcNAc...) Potential
	Disulfide bond	98 ↔ 108		By similarity
	Disulfide bond	122 ↔ 142		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5W188 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: F52CF35A8DC7D8B7	FASTA	147	17,316
	10 20 30 40 50 60 MWSLPPSRAL SCAPLLLLFS FQFLVTYAWR FQEEEEWNDQ KQIAVYLPPT LEFAVYTFNK 70 80 90 100 110 120 QSKDWYAYKL VPVLASWKEQ GYDKMTFSMN LQLGRTMCGK FEDDIDNCPF QESPELNNTC 130 140 TCFFTIGIEP WRTRFDLWNK TCSGGHS

References

[1]

"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL121894 Genomic DNA. Translation: CAH71435.1.
IPI	IPI00477679.
3D structure databases
HSSP	HSSP built from PDB template 1R4C based on UniProtKB P01034.
ProteinModelPortal	Q5W188.
ModBase	Search...
Polymorphism databases
DMDM	74748038.
Proteomic databases
PaxDb	Q5W188.
PRIDE	Q5W188.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
GeneCards	GC20M023530.
HGNC	HGNC:39552. CST9LP1.
neXtProt	NX_Q5W188.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG43835.
HOGENOM	HOG000231754.
HOVERGEN	HBG096568.
InParanoid	Q5W188.
OMA	VLDSWKE.
OrthoDB	EOG4BCDP4.
Gene expression databases
Genevestigator	Q5W188.
Family and domain databases
InterPro	IPR027213. CST9_like. IPR027214. Cystatin. IPR000010. Prot_inh_cystat. [Graphical view]
PANTHER	PTHR11413. PTHR11413. 1 hit. PTHR11413:SF22. PTHR11413:SF22. 1 hit.
Pfam	PF00031. Cystatin. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CST9P_HUMAN

Accession

Primary (citable) accession number: Q5W188

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	December 7, 2004
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.