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Q5W188

- CST9P_HUMAN

UniProt

Q5W188 - CST9P_HUMAN

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Protein

Putative cystatin-9-like protein CST9LP1

Gene
CST9LP1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

GO - Molecular functioni

  1. cysteine-type endopeptidase inhibitor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Thiol protease inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Putative cystatin-9-like protein CST9LP1
Alternative name(s):
Cystatin-9-like pseudogene 1
Gene namesi
Name:CST9LP1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:39552. CST9LP1.

Subcellular locationi

Secreted Reviewed prediction

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828 Reviewed predictionAdd
BLAST
Chaini29 – 147119Putative cystatin-9-like protein CST9LP1PRO_0000285800Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi98 ↔ 108 By similarity
Glycosylationi117 – 1171N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi122 ↔ 142 By similarity
Glycosylationi139 – 1391N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ5W188.
PRIDEiQ5W188.

Expressioni

Gene expression databases

GenevestigatoriQ5W188.

Structurei

3D structure databases

ProteinModelPortaliQ5W188.
SMRiQ5W188. Positions 51-142.

Family & Domainsi

Sequence similaritiesi

Belongs to the cystatin family.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG43835.
HOGENOMiHOG000231754.
HOVERGENiHBG096568.
InParanoidiQ5W188.
PhylomeDBiQ5W188.

Family and domain databases

InterProiIPR027214. Cystatin.
IPR000010. Prot_inh_cystat.
[Graphical view]
PANTHERiPTHR11413. PTHR11413. 1 hit.
PfamiPF00031. Cystatin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5W188-1 [UniParc]FASTAAdd to Basket

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MWSLPPSRAL SCAPLLLLFS FQFLVTYAWR FQEEEEWNDQ KQIAVYLPPT    50
LEFAVYTFNK QSKDWYAYKL VPVLASWKEQ GYDKMTFSMN LQLGRTMCGK 100
FEDDIDNCPF QESPELNNTC TCFFTIGIEP WRTRFDLWNK TCSGGHS 147
Length:147
Mass (Da):17,316
Last modified:December 7, 2004 - v1
Checksum:iF52CF35A8DC7D8B7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL121894 Genomic DNA. Translation: CAH71435.1.

Polymorphism databases

DMDMi74748038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL121894 Genomic DNA. Translation: CAH71435.1 .

3D structure databases

ProteinModelPortali Q5W188.
SMRi Q5W188. Positions 51-142.
ModBasei Search...
MobiDBi Search...

Polymorphism databases

DMDMi 74748038.

Proteomic databases

PaxDbi Q5W188.
PRIDEi Q5W188.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

GeneCardsi GC20M023530.
HGNCi HGNC:39552. CST9LP1.
neXtProti NX_Q5W188.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG43835.
HOGENOMi HOG000231754.
HOVERGENi HBG096568.
InParanoidi Q5W188.
PhylomeDBi Q5W188.

Gene expression databases

Genevestigatori Q5W188.

Family and domain databases

InterProi IPR027214. Cystatin.
IPR000010. Prot_inh_cystat.
[Graphical view ]
PANTHERi PTHR11413. PTHR11413. 1 hit.
Pfami PF00031. Cystatin. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCST9P_HUMAN
AccessioniPrimary (citable) accession number: Q5W188
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 7, 2004
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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