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Q5W188

- CST9P_HUMAN

UniProt

Q5W188 - CST9P_HUMAN

Protein

Putative cystatin-9-like protein CST9LP1

Gene

CST9LP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini
  1. Functioni

    GO - Molecular functioni

    1. cysteine-type endopeptidase inhibitor activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Protease inhibitor, Thiol protease inhibitor

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative cystatin-9-like protein CST9LP1
    Alternative name(s):
    Cystatin-9-like pseudogene 1
    Gene namesi
    Name:CST9LP1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Unplaced

    Organism-specific databases

    HGNCiHGNC:39552. CST9LP1.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2828Sequence AnalysisAdd
    BLAST
    Chaini29 – 147119Putative cystatin-9-like protein CST9LP1PRO_0000285800Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi98 ↔ 108By similarity
    Glycosylationi117 – 1171N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi122 ↔ 142By similarity
    Glycosylationi139 – 1391N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ5W188.
    PRIDEiQ5W188.

    Expressioni

    Gene expression databases

    GenevestigatoriQ5W188.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5W188.
    SMRiQ5W188. Positions 51-142.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cystatin family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG43835.
    HOGENOMiHOG000231754.
    HOVERGENiHBG096568.
    InParanoidiQ5W188.
    PhylomeDBiQ5W188.

    Family and domain databases

    InterProiIPR027214. Cystatin.
    IPR000010. Prot_inh_cystat.
    [Graphical view]
    PANTHERiPTHR11413. PTHR11413. 1 hit.
    PfamiPF00031. Cystatin. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q5W188-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWSLPPSRAL SCAPLLLLFS FQFLVTYAWR FQEEEEWNDQ KQIAVYLPPT    50
    LEFAVYTFNK QSKDWYAYKL VPVLASWKEQ GYDKMTFSMN LQLGRTMCGK 100
    FEDDIDNCPF QESPELNNTC TCFFTIGIEP WRTRFDLWNK TCSGGHS 147
    Length:147
    Mass (Da):17,316
    Last modified:December 7, 2004 - v1
    Checksum:iF52CF35A8DC7D8B7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL121894 Genomic DNA. Translation: CAH71435.1.

    Polymorphism databases

    DMDMi74748038.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL121894 Genomic DNA. Translation: CAH71435.1 .

    3D structure databases

    ProteinModelPortali Q5W188.
    SMRi Q5W188. Positions 51-142.
    ModBasei Search...
    MobiDBi Search...

    Polymorphism databases

    DMDMi 74748038.

    Proteomic databases

    PaxDbi Q5W188.
    PRIDEi Q5W188.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    GeneCardsi GC20M023530.
    HGNCi HGNC:39552. CST9LP1.
    neXtProti NX_Q5W188.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG43835.
    HOGENOMi HOG000231754.
    HOVERGENi HBG096568.
    InParanoidi Q5W188.
    PhylomeDBi Q5W188.

    Gene expression databases

    Genevestigatori Q5W188.

    Family and domain databases

    InterProi IPR027214. Cystatin.
    IPR000010. Prot_inh_cystat.
    [Graphical view ]
    PANTHERi PTHR11413. PTHR11413. 1 hit.
    Pfami PF00031. Cystatin. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
      , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
      Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCST9P_HUMAN
    AccessioniPrimary (citable) accession number: Q5W188
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 2007
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Could be the product of a pseudogene.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 20
      Human chromosome 20: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3