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Q5W188 (CST9P_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative cystatin-9-like protein CST9LP1
Alternative name(s):
Cystatin-9-like pseudogene 1
Gene names
Name:CST9LP1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length147 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceUncertain

General annotation (Comments)

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the cystatin family.

Caution

Could be the product of a pseudogene.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionProtease inhibitor
Thiol protease inhibitor
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncysteine-type endopeptidase inhibitor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2828 Potential
Chain29 – 147119Putative cystatin-9-like protein CST9LP1
PRO_0000285800

Amino acid modifications

Glycosylation1171N-linked (GlcNAc...) Potential
Glycosylation1391N-linked (GlcNAc...) Potential
Disulfide bond98 ↔ 108 By similarity
Disulfide bond122 ↔ 142 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5W188 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: F52CF35A8DC7D8B7

FASTA14717,316
        10         20         30         40         50         60 
MWSLPPSRAL SCAPLLLLFS FQFLVTYAWR FQEEEEWNDQ KQIAVYLPPT LEFAVYTFNK 

        70         80         90        100        110        120 
QSKDWYAYKL VPVLASWKEQ GYDKMTFSMN LQLGRTMCGK FEDDIDNCPF QESPELNNTC 

       130        140 
TCFFTIGIEP WRTRFDLWNK TCSGGHS 

« Hide

References

[1]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL121894 Genomic DNA. Translation: CAH71435.1.

3D structure databases

ProteinModelPortalQ5W188.
SMRQ5W188. Positions 51-142.
ModBaseSearch...
MobiDBSearch...

Polymorphism databases

DMDM74748038.

Proteomic databases

PaxDbQ5W188.
PRIDEQ5W188.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GeneCardsGC20M023530.
HGNCHGNC:39552. CST9LP1.
neXtProtNX_Q5W188.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG43835.
HOGENOMHOG000231754.
HOVERGENHBG096568.
InParanoidQ5W188.
PhylomeDBQ5W188.

Gene expression databases

GenevestigatorQ5W188.

Family and domain databases

InterProIPR027213. CST9_like.
IPR027214. Cystatin.
IPR000010. Prot_inh_cystat.
[Graphical view]
PANTHERPTHR11413. PTHR11413. 1 hit.
PTHR11413:SF22. PTHR11413:SF22. 1 hit.
PfamPF00031. Cystatin. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCST9P_HUMAN
AccessionPrimary (citable) accession number: Q5W188
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 7, 2004
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 20

Human chromosome 20: entries, gene names and cross-references to MIM