Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Translationally-controlled tumor protein

Gene

TPT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Translationally-controlled tumor proteinImported
Gene namesi
Name:TPT1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

HGNCiHGNC:12022. TPT1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Protein family/group databases

Allergomei3816. Hom s TCTP.

PTM / Processingi

Proteomic databases

EPDiQ5W0H4.
PaxDbiQ5W0H4.
PeptideAtlasiQ5W0H4.
PRIDEiQ5W0H4.

Expressioni

Gene expression databases

BgeeiQ5W0H4.
ExpressionAtlasiQ5W0H4. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-5003185.
STRINGi9606.ENSP00000431872.

Structurei

3D structure databases

ProteinModelPortaliQ5W0H4.
SMRiQ5W0H4. Positions 1-173.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCTP family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1727. Eukaryota.
ENOG4111FVP. LUCA.
GeneTreeiENSGT00390000006051.
HOGENOMiHOG000203361.
PhylomeDBiQ5W0H4.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5W0H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYRDLISH DEMFSDIYKI REIADGLCLE VEGKMVSRTE GNIDDSLIGG
60 70 80 90 100
NASAEGPEGE GTESTVITGV DIVMNHHLQE TSFTKEAYKK YIKDYMKSIK
110 120 130 140 150
GKLEEQRPER VKPFMTGAAE QIKHILANFK NYQFFIGENM NPDGMVALLD
160 170 180
YREDGVTPYM IFFKDGLEME KCVSTRKWVK INNVKKTF
Length:188
Mass (Da):21,526
Last modified:December 7, 2004 - v1
Checksum:i21D0EC8299101F73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138963 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000309246; ENSP00000339051; ENSG00000133112.
UCSCiuc058wue.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138963 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5W0H4.
SMRiQ5W0H4. Positions 1-173.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-5003185.
STRINGi9606.ENSP00000431872.

Protein family/group databases

Allergomei3816. Hom s TCTP.

Proteomic databases

EPDiQ5W0H4.
PaxDbiQ5W0H4.
PeptideAtlasiQ5W0H4.
PRIDEiQ5W0H4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000309246; ENSP00000339051; ENSG00000133112.
UCSCiuc058wue.1. human.

Organism-specific databases

HGNCiHGNC:12022. TPT1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1727. Eukaryota.
ENOG4111FVP. LUCA.
GeneTreeiENSGT00390000006051.
HOGENOMiHOG000203361.
PhylomeDBiQ5W0H4.

Miscellaneous databases

ChiTaRSiTPT1. human.

Gene expression databases

BgeeiQ5W0H4.
ExpressionAtlasiQ5W0H4. baseline and differential.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and analysis of human chromosome 13."
    Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
    Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (AUG-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "N-terminome analysis of the human mitochondrial proteome."
    Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.
    Proteomics 15:2519-2524(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiQ5W0H4_HUMAN
AccessioniPrimary (citable) accession number: Q5W0H4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: July 6, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.