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Protein
Submitted name:

Claudin-10

Gene

CLDN10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Claudin-10Imported
Gene namesi
Name:CLDN10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000134873.9
HGNCiHGNC:2033 CLDN10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 22HelicalSequence analysisAdd BLAST17
Transmembranei34 – 57HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Tight junctionSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134873

PTM / Processingi

Proteomic databases

EPDiQ5W075
PeptideAtlasiQ5W075
PRIDEiQ5W075

Expressioni

Gene expression databases

BgeeiENSG00000134873
ExpressionAtlasiQ5W075 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5W075
SMRiQ5W075
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the claudin family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IQ7E Eukaryota
ENOG410YF7U LUCA
GeneTreeiENSGT00760000119222

Family and domain databases

InterProiView protein in InterPro
IPR006187 Claudin
IPR003554 Claudin10
IPR004031 PMP22/EMP/MP20/Claudin
PANTHERiPTHR12002 PTHR12002, 1 hit
PTHR12002:SF13 PTHR12002:SF13, 1 hit
PfamiView protein in Pfam
PF00822 PMP22_Claudin, 1 hit

Sequencei

Sequence statusi: Complete.

Q5W075-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAAVSLGFF GSIFALFGMK CTKVGGSDKA KAKIACLAGI VFILSGLCSM
60 70
TGCSLYANKI TTEFFDPLFV EQK
Length:73
Mass (Da):7,709
Last modified:December 7, 2004 - v1
Checksum:i4361A2468A46E5F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139376 Genomic DNA No translation available.
AL357061 Genomic DNA No translation available.
AL627382 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000376855; ENSP00000366051; ENSG00000134873
UCSCiuc058xtz.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5W075_HUMAN
AccessioniPrimary (citable) accession number: Q5W075
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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