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Protein
Submitted name:

Interleukin 2 receptor, alpha, isoform CRA_b

Gene

IL2RA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 2 receptor, alpha, isoform CRA_bImported
Submitted name:
Interleukin-2 receptor subunit alphaImported
Gene namesi
Name:IL2RAImported
ORF Names:hCG_23482Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000134460.15
HGNCiHGNC:6008 IL2RA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei167 – 189HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134460

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501410599822 – 200Sequence analysisAdd BLAST179

Proteomic databases

PeptideAtlasiQ5W005
PRIDEiQ5W005

Expressioni

Gene expression databases

BgeeiENSG00000134460
ExpressionAtlasiQ5W005 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ5W005
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 79SushiInterPro annotationAdd BLAST54

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000018872
HOGENOMiHOG000113044
HOVERGENiHBG052109

Family and domain databases

InterProiView protein in InterPro
IPR015486 IL-2_rcpt_alpha
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PANTHERiPTHR10573 PTHR10573, 2 hits
PfamiView protein in Pfam
PF00084 Sushi, 1 hit
SUPFAMiSSF57535 SSF57535, 1 hit

Sequencei

Sequence statusi: Complete.

Q5W005-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSYLLMWGL LTFIMVPGCQ AELCDDDPPE IPHATFKAMA YKEGTMLNCE
60 70 80 90 100
CKRGFRRIKS GSLYMLCTGN SSHSSWDNQC QCTSSATRNT TKQVTPQPEE
110 120 130 140 150
QKERKTTEMQ SPMQPVDQAS LPGEEKPQAS PEGRPESETS CLVTTTDFQI
160 170 180 190 200
QTEMAATMET SIFTTEYQVA VAGCVFLLIS VLLLSGLTWQ RRQRKSRRTI
Length:200
Mass (Da):22,454
Last modified:December 7, 2004 - v1
Checksum:i7793254ABA60CEB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137186 Genomic DNA No translation available.
AL157395 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86413.1
RefSeqiNP_001295171.1, NM_001308242.1
UniGeneiHs.231367

Genome annotation databases

EnsembliENST00000379954; ENSP00000369287; ENSG00000134460
GeneIDi3559
UCSCiuc009xih.3 human

Similar proteinsi

Entry informationi

Entry nameiQ5W005_HUMAN
AccessioniPrimary (citable) accession number: Q5W005
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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