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Protein

Hippocampus abundant transcript-like protein 2

Gene

MFSD14C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Hippocampus abundant transcript-like protein 2Imported
Alternative name(s):
Major facilitator superfamily domain-containing 14CImported
Gene namesi
Name:MFSD14CImported
Synonyms:HIATL2Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:23672. MFSD14C.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4949ExtracellularSequence analysisAdd
BLAST
Transmembranei50 – 7021HelicalSequence analysisAdd
BLAST
Topological domaini71 – 8212CytoplasmicSequence analysisAdd
BLAST
Transmembranei83 – 10321HelicalSequence analysisAdd
BLAST
Topological domaini104 – 1118ExtracellularSequence analysis
Transmembranei112 – 13221HelicalSequence analysisAdd
BLAST
Topological domaini133 – 1342CytoplasmicSequence analysis

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 134134Hippocampus abundant transcript-like protein 2PRO_0000239231Add
BLAST

Proteomic databases

PaxDbiQ5VZR4.
PeptideAtlasiQ5VZR4.

PTM databases

iPTMnetiQ5VZR4.
PhosphoSiteiQ5VZR4.

Expressioni

Gene expression databases

BgeeiENSG00000196312.
CleanExiHS_HIATL2.
ExpressionAtlasiQ5VZR4. baseline and differential.
GenevisibleiQ5VZR4. HS.

Interactioni

Protein-protein interaction databases

IntActiQ5VZR4. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ5VZR4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2816. Eukaryota.
ENOG410ZVCA. LUCA.
GeneTreeiENSGT00510000046502.
HOGENOMiHOG000206711.
InParanoidiQ5VZR4.
PhylomeDBiQ5VZR4.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005829. Sugar_transporter_CS.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VZR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVEPPPELE EKAASEPEAG AMPEKRAGAQ AAGSTWLQGF GPPSVYHAAI
60 70 80 90 100
VIFLEFFAWG LLTTPMLTVL HETFSQHTFL MNGLIQGVKG LLSFLSAPLI
110 120 130
GALSDVWGRK PFLLGTVFFT CFPIPLMRIS PCQA
Length:134
Mass (Da):14,477
Last modified:December 7, 2004 - v1
Checksum:i453019488F8F542E
GO

Sequence cautioni

The sequence BC005058 differs from that shown.The sequence differs at the 3' end.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158827, AL445670 Genomic DNA. Translation: CAH72564.1.
AL445670, AL158827 Genomic DNA. Translation: CAI15052.1.
BC005058 mRNA. No translation available.
UniGeneiHs.610084.

Genome annotation databases

EnsembliENST00000375223; ENSP00000364371; ENSG00000196312.
UCSCiuc064upl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158827, AL445670 Genomic DNA. Translation: CAH72564.1.
AL445670, AL158827 Genomic DNA. Translation: CAI15052.1.
BC005058 mRNA. No translation available.
UniGeneiHs.610084.

3D structure databases

ProteinModelPortaliQ5VZR4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5VZR4. 1 interaction.

PTM databases

iPTMnetiQ5VZR4.
PhosphoSiteiQ5VZR4.

Proteomic databases

PaxDbiQ5VZR4.
PeptideAtlasiQ5VZR4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375223; ENSP00000364371; ENSG00000196312.
UCSCiuc064upl.1. human.

Organism-specific databases

GeneCardsiHIATL2.
HGNCiHGNC:23672. MFSD14C.
neXtProtiNX_Q5VZR4.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2816. Eukaryota.
ENOG410ZVCA. LUCA.
GeneTreeiENSGT00510000046502.
HOGENOMiHOG000206711.
InParanoidiQ5VZR4.
PhylomeDBiQ5VZR4.

Miscellaneous databases

PROiQ5VZR4.

Gene expression databases

BgeeiENSG00000196312.
CleanExiHS_HIATL2.
ExpressionAtlasiQ5VZR4. baseline and differential.
GenevisibleiQ5VZR4. HS.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005829. Sugar_transporter_CS.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMF14C_HUMAN
AccessioniPrimary (citable) accession number: Q5VZR4
Secondary accession number(s): Q9BSG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: December 7, 2004
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.