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Protein

MORN repeat-containing protein 5

Gene

MORN5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
MORN repeat-containing protein 5
Gene namesi
Name:MORN5
Synonyms:C9orf113, C9orf18
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000185681.12.
HGNCiHGNC:17841. MORN5.

Pathology & Biotechi

Organism-specific databases

DisGeNETi254956.
OpenTargetsiENSG00000185681.
PharmGKBiPA25975.

Polymorphism and mutation databases

BioMutaiMORN5.
DMDMi74747757.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002928401 – 161MORN repeat-containing protein 5Add BLAST161

Proteomic databases

PaxDbiQ5VZ52.
PeptideAtlasiQ5VZ52.
PRIDEiQ5VZ52.

PTM databases

iPTMnetiQ5VZ52.
PhosphoSitePlusiQ5VZ52.

Expressioni

Gene expression databases

BgeeiENSG00000185681.
CleanExiHS_MORN5.
ExpressionAtlasiQ5VZ52. baseline and differential.
GenevisibleiQ5VZ52. HS.

Interactioni

Protein-protein interaction databases

BioGridi129063. 3 interactors.
IntActiQ5VZ52. 2 interactors.
STRINGi9606.ENSP00000362869.

Structurei

3D structure databases

ProteinModelPortaliQ5VZ52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati8 – 30MORN 1Add BLAST23
Repeati31 – 53MORN 2Add BLAST23
Repeati54 – 75MORN 3Add BLAST22

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0231. Eukaryota.
COG4642. LUCA.
GeneTreeiENSGT00390000018089.
HOGENOMiHOG000007133.
HOVERGENiHBG059322.
InParanoidiQ5VZ52.
OMAiWIVRTCR.
OrthoDBiEOG091G0C1Z.
PhylomeDBiQ5VZ52.
TreeFamiTF327409.

Family and domain databases

InterProiView protein in InterPro
IPR003409. MORN.
PfamiView protein in Pfam
PF02493. MORN. 3 hits.
SMARTiView protein in SMART
SM00698. MORN. 2 hits.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q5VZ52-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEYTGSKYIG EYVDGRMEGK AKYILPTETI YVGEMKDGMF HGEGTLYFPS
60 70 80 90 100
GSQYDAIWEN GLAIKGTYTF SDGLHYDEKN WHYCDGYDRR FYTEILNGLK
110 120 130 140 150
PAGMAQLTNM DPPRKIPKGY YDCGDGFYNP VTRVVKDYRN RFLRNADDDE
160
HEWITRTCRK G
Length:161
Mass (Da):18,731
Last modified:December 7, 2004 - v1
Checksum:iC0DA34ED1D015866
GO
Isoform 2 (identifier: Q5VZ52-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     147-161: DDDEHEWITRTCRKG → GRFLPTLQHVFSSPTYEYVHLYVQMYAHT

Note: No experimental confirmation available.
Show »
Length:175
Mass (Da):20,356
Checksum:i1AE8178BAD0B6C65
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti45T → A in BAC87653 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_055496147 – 161DDDEH…TCRKG → GRFLPTLQHVFSSPTYEYVH LYVQMYAHT in isoform 2. 1 PublicationAdd BLAST15

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK128877 mRNA. Translation: BAC87653.1.
AK302081 mRNA. Translation: BAH13621.1.
AL162423, AL162424 Genomic DNA. Translation: CAH73981.1.
AL162424, AL162423 Genomic DNA. Translation: CAI14705.1.
CH471090 Genomic DNA. Translation: EAW87512.1.
BC133690 mRNA. Translation: AAI33691.1.
CCDSiCCDS6836.1. [Q5VZ52-1]
RefSeqiNP_001273757.1. NM_001286828.1.
NP_940871.2. NM_198469.3. [Q5VZ52-1]
XP_005251934.1. XM_005251877.4. [Q5VZ52-2]
UniGeneiHs.71428.

Genome annotation databases

EnsembliENST00000373764; ENSP00000362869; ENSG00000185681. [Q5VZ52-1]
GeneIDi254956.
KEGGihsa:254956.
UCSCiuc004blw.4. human. [Q5VZ52-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiMORN5_HUMAN
AccessioniPrimary (citable) accession number: Q5VZ52
Secondary accession number(s): B7Z7I5, Q6ZQN1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 7, 2004
Last modified: September 27, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM