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Q5VYP0

- S31A3_HUMAN

UniProt

Q5VYP0 - S31A3_HUMAN

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Protein

Spermatogenesis-associated protein 31A3

Gene

SPATA31A3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

May play a role in spermatogenesis.By similarity

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. spermatogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 31A3
Alternative name(s):
Protein FAM75A3
Gene namesi
Name:SPATA31A3
Synonyms:FAM75A3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:32003. SPATA31A3.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162387867.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13471347Spermatogenesis-associated protein 31A3PRO_0000313018Add
BLAST

Proteomic databases

PaxDbiQ5VYP0.
PRIDEiQ5VYP0.

PTM databases

PhosphoSiteiQ5VYP0.

Expressioni

Gene expression databases

BgeeiQ5VYP0.
CleanExiHS_FAM75A3.
GenevestigatoriQ5VYP0.

Structurei

3D structure databases

ProteinModelPortaliQ5VYP0.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi120 – 228109Pro-richAdd
BLAST

Sequence similaritiesi

Belongs to the SPATA31 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG45889.
HOGENOMiHOG000015250.
HOVERGENiHBG107892.
InParanoidiQ5VYP0.
OMAiWISERSS.
OrthoDBiEOG7SFHVW.
PhylomeDBiQ5VYP0.
TreeFamiTF338531.

Family and domain databases

InterProiIPR027970. DUF4599.
[Graphical view]
PfamiPF15371. DUF4599. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VYP0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR
60 70 80 90 100
CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LEETSDLLSQ
110 120 130 140 150
LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS
160 170 180 190 200
LLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP
210 220 230 240 250
PALFPHPPHT PDPLACSLPP PKGFTAPPLR DSTLITPSHC DSVALPLGTV
260 270 280 290 300
PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD
310 320 330 340 350
HLSRHPPETC QMEAGSLFLL SSDGQNVVGI QVTETAKVNI WEEKENVGSF
360 370 380 390 400
TNRMTPEKHL NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKLSD
410 420 430 440 450
PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM
460 470 480 490 500
SNVCPIQRET TMSPLLFQAQ PLSHLGPECQ PFISSTPQFR PTPMAQAEAQ
510 520 530 540 550
AHLQSSFPVL SPAFPSLIQN TGVACPASQN KVQALSLPET QHPEWPLLRR
560 570 580 590 600
QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE
610 620 630 640 650
QHIKKWIIQH WGNLGRIQES LDLMQLQDES PGTSQAKGKP SPWQSSMSTG
660 670 680 690 700
ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE
710 720 730 740 750
LERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVRV
760 770 780 790 800
RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL
810 820 830 840 850
GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG
860 870 880 890 900
AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR
910 920 930 940 950
GIPSWNDHEP LKPPPAGQEG RWPSKPLTYS LTGSTQQSRS LGAQSSKAGE
960 970 980 990 1000
TREAVPQCRV PLETCMLANL QATSEDVHGF EAPGTSKSSL HPRVSVSQDP
1010 1020 1030 1040 1050
RKLCLMEEVV SEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV
1060 1070 1080 1090 1100
SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRK PNCQGSCKSQ
1110 1120 1130 1140 1150
RPMFPPIHKS EKFRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL
1160 1170 1180 1190 1200
LPSKKQPPSV SPFGENIKQI FQWIFSKKKS KPAPVTAESQ KTVKNRSCVY
1210 1220 1230 1240 1250
SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH
1260 1270 1280 1290 1300
RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ
1310 1320 1330 1340
WGLRHPQILH PKKAVSPVSP PQHWPKTSGA SSHHHHCPRH CLLWEGI
Length:1,347
Mass (Da):148,706
Last modified:December 7, 2004 - v1
Checksum:i5C5457992FA6FE8E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1152 – 11521P → Q in CAB45741. (PubMed:17974005)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL353770 Genomic DNA. Translation: CAH73359.1.
AL080148 mRNA. Translation: CAB45741.1.
PIRiT12532.
RefSeqiNP_001076593.1. NM_001083124.1.
UniGeneiHs.632078.

Genome annotation databases

GeneIDi727830.
KEGGihsa:727830.
UCSCiuc010mmj.3. human.

Polymorphism databases

DMDMi74747695.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL353770 Genomic DNA. Translation: CAH73359.1 .
AL080148 mRNA. Translation: CAB45741.1 .
PIRi T12532.
RefSeqi NP_001076593.1. NM_001083124.1.
UniGenei Hs.632078.

3D structure databases

ProteinModelPortali Q5VYP0.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q5VYP0.

Polymorphism databases

DMDMi 74747695.

Proteomic databases

PaxDbi Q5VYP0.
PRIDEi Q5VYP0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 727830.
KEGGi hsa:727830.
UCSCi uc010mmj.3. human.

Organism-specific databases

CTDi 727830.
GeneCardsi GC09P040700.
H-InvDB HIX0008058.
HIX0025865.
HIX0058660.
HIX0058661.
HIX0201371.
HGNCi HGNC:32003. SPATA31A3.
neXtProti NX_Q5VYP0.
PharmGKBi PA162387867.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG45889.
HOGENOMi HOG000015250.
HOVERGENi HBG107892.
InParanoidi Q5VYP0.
OMAi WISERSS.
OrthoDBi EOG7SFHVW.
PhylomeDBi Q5VYP0.
TreeFami TF338531.

Miscellaneous databases

GenomeRNAii 727830.
NextBioi 125249.
PROi Q5VYP0.

Gene expression databases

Bgeei Q5VYP0.
CleanExi HS_FAM75A3.
Genevestigatori Q5VYP0.

Family and domain databases

InterProi IPR027970. DUF4599.
[Graphical view ]
Pfami PF15371. DUF4599. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 340-1347.
    Tissue: Testis.

Entry informationi

Entry nameiS31A3_HUMAN
AccessioniPrimary (citable) accession number: Q5VYP0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 7, 2004
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3