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Q5VYP0 (S31A3_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Spermatogenesis-associated protein 31A3
Alternative name(s):
Protein FAM75A3
Gene names
Name:SPATA31A3
Synonyms:FAM75A3
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1347 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May play a role in spermatogenesis By similarity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the SPATA31 family.

Ontologies

Keywords
   Biological processDifferentiation
Spermatogenesis
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell differentiation

Inferred from electronic annotation. Source: UniProtKB-KW

spermatogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 13471347Spermatogenesis-associated protein 31A3
PRO_0000313018

Regions

Transmembrane23 – 4321Helical; Potential
Compositional bias120 – 228109Pro-rich

Experimental info

Sequence conflict11521P → Q in CAB45741. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q5VYP0 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: 5C5457992FA6FE8E

FASTA1,347148,706
        10         20         30         40         50         60 
MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR CDDPPSPSPG 

        70         80         90        100        110        120 
KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LEETSDLLSQ LQSLLGPHLD KGDFGQLSGP 

       130        140        150        160        170        180 
DPPGEVGERA PDGASQSSHE PMEDAAPILS LLASPDPQAK HPQDLASTPS PGPMTTSVSS 

       190        200        210        220        230        240 
LSASQPPEPS LPLEHPSPEP PALFPHPPHT PDPLACSLPP PKGFTAPPLR DSTLITPSHC 

       250        260        270        280        290        300 
DSVALPLGTV PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD 

       310        320        330        340        350        360 
HLSRHPPETC QMEAGSLFLL SSDGQNVVGI QVTETAKVNI WEEKENVGSF TNRMTPEKHL 

       370        380        390        400        410        420 
NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKLSD PRLWQESFWK NYSQLFWGLP 

       430        440        450        460        470        480 
SLHSESLVAN AWVTDRSYTL QSPPFLFNEM SNVCPIQRET TMSPLLFQAQ PLSHLGPECQ 

       490        500        510        520        530        540 
PFISSTPQFR PTPMAQAEAQ AHLQSSFPVL SPAFPSLIQN TGVACPASQN KVQALSLPET 

       550        560        570        580        590        600 
QHPEWPLLRR QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE 

       610        620        630        640        650        660 
QHIKKWIIQH WGNLGRIQES LDLMQLQDES PGTSQAKGKP SPWQSSMSTG ESSKEAQKVK 

       670        680        690        700        710        720 
FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE LERNLRKPLR SDSGSDLLRC 

       730        740        750        760        770        780 
TERTHIENIL KAHMGRNLGQ TNEGLIPVRV RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK 

       790        800        810        820        830        840 
ACVNTAQVLS FLEPCTQQGL GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA 

       850        860        870        880        890        900 
GPSSATCESG AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR 

       910        920        930        940        950        960 
GIPSWNDHEP LKPPPAGQEG RWPSKPLTYS LTGSTQQSRS LGAQSSKAGE TREAVPQCRV 

       970        980        990       1000       1010       1020 
PLETCMLANL QATSEDVHGF EAPGTSKSSL HPRVSVSQDP RKLCLMEEVV SEFEPGMATK 

      1030       1040       1050       1060       1070       1080 
SETQPQVCAA VVLLPDGQAS VVPHASENLV SQVPQGHLQS MPTGNMRASQ ELHDLMAARR 

      1090       1100       1110       1120       1130       1140 
SKLVHEEPRK PNCQGSCKSQ RPMFPPIHKS EKFRKPNLEK HEERLEGLRT PQLTPVRKTE 

      1150       1160       1170       1180       1190       1200 
DTHQDEGVQL LPSKKQPPSV SPFGENIKQI FQWIFSKKKS KPAPVTAESQ KTVKNRSCVY 

      1210       1220       1230       1240       1250       1260 
SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH RHLFYSEHGR 

      1270       1280       1290       1300       1310       1320 
ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ WGLRHPQILH PKKAVSPVSP 

      1330       1340 
PQHWPKTSGA SSHHHHCPRH CLLWEGI 

« Hide

References

[1]"DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. expand/collapse author list , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 340-1347.
Tissue: Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL353770 Genomic DNA. Translation: CAH73359.1.
AL080148 mRNA. Translation: CAB45741.1.
PIRT12532.
RefSeqNP_001076593.1. NM_001083124.1.
UniGeneHs.632078.

3D structure databases

ProteinModelPortalQ5VYP0.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ5VYP0.

Polymorphism databases

DMDM74747695.

Proteomic databases

PaxDbQ5VYP0.
PRIDEQ5VYP0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000356699; ENSP00000349132; ENSG00000147926.
GeneID727830.
KEGGhsa:727830.
UCSCuc010mmj.3. human.

Organism-specific databases

CTD727830.
GeneCardsGC09P040700.
H-InvDBHIX0008058.
HIX0025865.
HIX0058660.
HIX0058661.
HIX0201371.
HGNCHGNC:32003. SPATA31A3.
neXtProtNX_Q5VYP0.
PharmGKBPA162387867.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG45889.
HOGENOMHOG000015250.
HOVERGENHBG107892.
InParanoidQ5VYP0.
OMAWISERSS.
OrthoDBEOG7SFHVW.
PhylomeDBQ5VYP0.
TreeFamTF338531.

Gene expression databases

BgeeQ5VYP0.
CleanExHS_FAM75A3.
GenevestigatorQ5VYP0.

Family and domain databases

InterProIPR027970. DUF4599.
[Graphical view]
PfamPF15371. DUF4599. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi727830.
NextBio125249.
PROQ5VYP0.

Entry information

Entry nameS31A3_HUMAN
AccessionPrimary (citable) accession number: Q5VYP0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 7, 2004
Last modified: April 16, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 9

Human chromosome 9: entries, gene names and cross-references to MIM