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Q5VYP0

- S31A3_HUMAN

UniProt

Q5VYP0 - S31A3_HUMAN

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Protein
Spermatogenesis-associated protein 31A3
Gene
SPATA31A3, FAM75A3
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

May play a role in spermatogenesis By similarity.

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. spermatogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 31A3
Alternative name(s):
Protein FAM75A3
Gene namesi
Synonyms:FAM75A3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:32003. SPATA31A3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162387867.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13471347Spermatogenesis-associated protein 31A3
PRO_0000313018Add
BLAST

Proteomic databases

PaxDbiQ5VYP0.
PRIDEiQ5VYP0.

PTM databases

PhosphoSiteiQ5VYP0.

Expressioni

Gene expression databases

BgeeiQ5VYP0.
CleanExiHS_FAM75A3.
GenevestigatoriQ5VYP0.

Structurei

3D structure databases

ProteinModelPortaliQ5VYP0.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi120 – 228109Pro-rich
Add
BLAST

Sequence similaritiesi

Belongs to the SPATA31 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG45889.
HOGENOMiHOG000015250.
HOVERGENiHBG107892.
InParanoidiQ5VYP0.
OMAiWISERSS.
OrthoDBiEOG7SFHVW.
PhylomeDBiQ5VYP0.
TreeFamiTF338531.

Family and domain databases

InterProiIPR027970. DUF4599.
[Graphical view]
PfamiPF15371. DUF4599. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VYP0-1 [UniParc]FASTAAdd to Basket

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MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR     50
CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LEETSDLLSQ 100
LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS 150
LLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP 200
PALFPHPPHT PDPLACSLPP PKGFTAPPLR DSTLITPSHC DSVALPLGTV 250
PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD 300
HLSRHPPETC QMEAGSLFLL SSDGQNVVGI QVTETAKVNI WEEKENVGSF 350
TNRMTPEKHL NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKLSD 400
PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM 450
SNVCPIQRET TMSPLLFQAQ PLSHLGPECQ PFISSTPQFR PTPMAQAEAQ 500
AHLQSSFPVL SPAFPSLIQN TGVACPASQN KVQALSLPET QHPEWPLLRR 550
QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE 600
QHIKKWIIQH WGNLGRIQES LDLMQLQDES PGTSQAKGKP SPWQSSMSTG 650
ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE 700
LERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVRV 750
RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL 800
GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG 850
AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR 900
GIPSWNDHEP LKPPPAGQEG RWPSKPLTYS LTGSTQQSRS LGAQSSKAGE 950
TREAVPQCRV PLETCMLANL QATSEDVHGF EAPGTSKSSL HPRVSVSQDP 1000
RKLCLMEEVV SEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV 1050
SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRK PNCQGSCKSQ 1100
RPMFPPIHKS EKFRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL 1150
LPSKKQPPSV SPFGENIKQI FQWIFSKKKS KPAPVTAESQ KTVKNRSCVY 1200
SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH 1250
RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ 1300
WGLRHPQILH PKKAVSPVSP PQHWPKTSGA SSHHHHCPRH CLLWEGI 1347
Length:1,347
Mass (Da):148,706
Last modified:December 7, 2004 - v1
Checksum:i5C5457992FA6FE8E
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1152 – 11521P → Q in CAB45741. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL353770 Genomic DNA. Translation: CAH73359.1.
AL080148 mRNA. Translation: CAB45741.1.
CCDSiCCDS47969.1.
PIRiT12532.
RefSeqiNP_001076593.1. NM_001083124.1.
UniGeneiHs.632078.

Genome annotation databases

EnsembliENST00000356699; ENSP00000349132; ENSG00000147926.
GeneIDi727830.
KEGGihsa:727830.
UCSCiuc010mmj.3. human.

Polymorphism databases

DMDMi74747695.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL353770 Genomic DNA. Translation: CAH73359.1 .
AL080148 mRNA. Translation: CAB45741.1 .
CCDSi CCDS47969.1.
PIRi T12532.
RefSeqi NP_001076593.1. NM_001083124.1.
UniGenei Hs.632078.

3D structure databases

ProteinModelPortali Q5VYP0.
ModBasei Search...

PTM databases

PhosphoSitei Q5VYP0.

Polymorphism databases

DMDMi 74747695.

Proteomic databases

PaxDbi Q5VYP0.
PRIDEi Q5VYP0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000356699 ; ENSP00000349132 ; ENSG00000147926 .
GeneIDi 727830.
KEGGi hsa:727830.
UCSCi uc010mmj.3. human.

Organism-specific databases

CTDi 727830.
GeneCardsi GC09P040700.
H-InvDB HIX0008058.
HIX0025865.
HIX0058660.
HIX0058661.
HIX0201371.
HGNCi HGNC:32003. SPATA31A3.
neXtProti NX_Q5VYP0.
PharmGKBi PA162387867.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG45889.
HOGENOMi HOG000015250.
HOVERGENi HBG107892.
InParanoidi Q5VYP0.
OMAi WISERSS.
OrthoDBi EOG7SFHVW.
PhylomeDBi Q5VYP0.
TreeFami TF338531.

Miscellaneous databases

GenomeRNAii 727830.
NextBioi 125249.
PROi Q5VYP0.

Gene expression databases

Bgeei Q5VYP0.
CleanExi HS_FAM75A3.
Genevestigatori Q5VYP0.

Family and domain databases

InterProi IPR027970. DUF4599.
[Graphical view ]
Pfami PF15371. DUF4599. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 340-1347.
    Tissue: Testis.

Entry informationi

Entry nameiS31A3_HUMAN
AccessioniPrimary (citable) accession number: Q5VYP0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 7, 2004
Last modified: July 9, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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