Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Partitioning defective 3 homolog

Gene

PARD3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Partitioning defective 3 homologImported
Gene namesi
Name:PARD3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:16051. PARD3.

PTM / Processingi

Proteomic databases

PaxDbiQ5VWU8.
PeptideAtlasiQ5VWU8.
PRIDEiQ5VWU8.

Expressioni

Gene expression databases

BgeeiENSG00000148498.
ExpressionAtlasiQ5VWU8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000363921.

Structurei

3D structure databases

ProteinModelPortaliQ5VWU8.
SMRiQ5VWU8. Positions 2-82, 451-549, 582-685.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini271 – 34777PDZ (DHR)InterPro annotationAdd
BLAST
Domaini461 – 54686PDZ (DHR)InterPro annotationAdd
BLAST
Domaini590 – 66576PDZ (DHR)InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 3 PDZ (DHR) domains.UniRule annotation

Phylogenomic databases

eggNOGiENOG410ITAJ. Eukaryota.
ENOG410ZDVK. LUCA.
GeneTreeiENSGT00760000119017.
HOGENOMiHOG000232109.
HOVERGENiHBG053508.

Family and domain databases

Gene3Di2.30.42.10. 3 hits.
InterProiIPR021922. DUF3534.
IPR001478. PDZ.
[Graphical view]
PfamiPF12053. DUF3534. 1 hit.
PF00595. PDZ. 2 hits.
[Graphical view]
SMARTiSM00228. PDZ. 3 hits.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 3 hits.
PROSITEiPS50106. PDZ. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VWU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVTVCFGRT RVVVPCGDGH MKVFSLIQQA VTRYRKAIAK DPNYWIQVHR
60 70 80 90 100
LEHGDGGILD LDDILCDVAD DKDRLVAVFD EQDPHHGGDG TSASSTGTQS
110 120 130 140 150
PEIFGSELGT NNVSAFQPYQ ATSEIEVTPS VLRANMPLHV RRSSDPALIG
160 170 180 190 200
LSTSVSDSNF SSEEPSRKNP TRWSTTAGFL KQNTAGSPKT CDRKKDENYR
210 220 230 240 250
SLPRDTSNWS NQFQRDNARS SLSASHPMVG KWLEKQEQDE DGTEEDNSRV
260 270 280 290 300
EPVGHADTGL EHIPNFSLDD MVKLVEVPND GGPLGIHVVP FSARGGRTLG
310 320 330 340 350
LLVKRLEKGG KAEHENLFRE NDCIVRINDG DLRNRRFEQA QHMFRQAMRT
360 370 380 390 400
PIIWFHVVPA ANKEQYEQLS QSEKNNYYSS RFSPDSQYID NRSVNSAGLH
410 420 430 440 450
TVQRAPRLNH PPEQIDSHSR LPHSAHPSGK PPSAPASAPQ NVFSTTVSSG
460 470 480 490 500
YNTKKIGKRL NIQLKKGTEG LGFSITSRDV TIGGSAPIYV KNILPRGAAI
510 520 530 540 550
QDGRLKAGDR LIEVNGVDLV GKSQEEVVSL LRSTKMEGTV SLLVFRQEDA
560 570 580 590 600
FHPRELNAEP SQMQIPKETK AEDEDIVLTP DGTREFLTFE VPLNDSGSAG
610 620 630 640 650
LGVSVKGNRS KENHADLGIF VKSIINGGAA SKDGRLRVND QLIAVNGESL
660 670 680 690 700
LGKTNQDAME TLRRSMSTEG NKRGMIQLIV ARRISKCNEL KSPGSPPGPE
710 720 730 740 750
LPIETALDDR ERRISHSLYS GIEGLDESPS RNAALSRIMG KYQLSPTVNM
760 770 780 790 800
PQDDTVIIED DRLPVLPPHL SDQSSSSSHD DVGFVTADAG TWAKAAISDS
810 820 830 840 850
ADCSLSPDVD PVLAFQREGF GRQIADETKL NTVDDQKAGS PSRDVGPSLG
860 870 880 890 900
LKKSSSLESL QTAVAEVTLN GDIPFHRPRP RIIRGRGCNE SFRAAIDKSY
910 920 930 940 950
DKPAVDDDDE GMETLEEDTE ESSRSGRESV STASDQPSHS LERQMNGNQE
960 970 980 990 1000
KGDKTDRKKD KTGKEKKKDR DKEKDKMKAK KGMLKGLGDM FSLAKLKPEK

R
Length:1,001
Mass (Da):110,000
Last modified:December 7, 2004 - v1
Checksum:i8BEAC4DB35D008E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138768 Genomic DNA. No translation available.
AL160409 Genomic DNA. No translation available.
AL360233 Genomic DNA. No translation available.
AL390766 Genomic DNA. No translation available.
AL392123 Genomic DNA. No translation available.
AL450337 Genomic DNA. No translation available.
AL590039 Genomic DNA. No translation available.
AL603963 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000374773; ENSP00000363905; ENSG00000148498.
UCSCiuc057srq.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138768 Genomic DNA. No translation available.
AL160409 Genomic DNA. No translation available.
AL360233 Genomic DNA. No translation available.
AL390766 Genomic DNA. No translation available.
AL392123 Genomic DNA. No translation available.
AL450337 Genomic DNA. No translation available.
AL590039 Genomic DNA. No translation available.
AL603963 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5VWU8.
SMRiQ5VWU8. Positions 2-82, 451-549, 582-685.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000363921.

Proteomic databases

PaxDbiQ5VWU8.
PeptideAtlasiQ5VWU8.
PRIDEiQ5VWU8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000374773; ENSP00000363905; ENSG00000148498.
UCSCiuc057srq.1. human.

Organism-specific databases

HGNCiHGNC:16051. PARD3.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ITAJ. Eukaryota.
ENOG410ZDVK. LUCA.
GeneTreeiENSGT00760000119017.
HOGENOMiHOG000232109.
HOVERGENiHBG053508.

Miscellaneous databases

ChiTaRSiPARD3. human.

Gene expression databases

BgeeiENSG00000148498.
ExpressionAtlasiQ5VWU8. baseline and differential.

Family and domain databases

Gene3Di2.30.42.10. 3 hits.
InterProiIPR021922. DUF3534.
IPR001478. PDZ.
[Graphical view]
PfamiPF12053. DUF3534. 1 hit.
PF00595. PDZ. 2 hits.
[Graphical view]
SMARTiSM00228. PDZ. 3 hits.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 3 hits.
PROSITEiPS50106. PDZ. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5VWU8_HUMAN
AccessioniPrimary (citable) accession number: Q5VWU8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.