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Protein

Protein FAM208B

Gene

FAM208B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM208B
Gene namesi
Name:FAM208B
Synonyms:C10orf18, KIAA2006
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:23484. FAM208B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiFAM208B.
DMDMi74747424.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 24302430Protein FAM208BPRO_0000299542Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei19 – 191PhosphoserineCombined sources
Modified residuei384 – 3841PhosphoserineCombined sources
Modified residuei1025 – 10251PhosphoserineCombined sources
Modified residuei1087 – 10871PhosphoserineCombined sources
Modified residuei2009 – 20091PhosphoserineCombined sources
Modified residuei2037 – 20371PhosphoserineCombined sources
Modified residuei2062 – 20621PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ5VWN6.
MaxQBiQ5VWN6.
PaxDbiQ5VWN6.
PRIDEiQ5VWN6.

PTM databases

iPTMnetiQ5VWN6.
PhosphoSiteiQ5VWN6.

Expressioni

Gene expression databases

BgeeiQ5VWN6.
CleanExiHS_C10orf18.
ExpressionAtlasiQ5VWN6. baseline and differential.
GenevisibleiQ5VWN6. HS.

Organism-specific databases

HPAiHPA038042.
HPA038043.
HPA061547.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
A8K5H93EBI-10172380,EBI-10174421
Q8N5D43EBI-10172380,EBI-10266435
ATRIPQ8WXE13EBI-10172380,EBI-747353
CARD9Q9H2573EBI-10172380,EBI-751319
ERHP840903EBI-10172380,EBI-711389
FBF1Q8TES7-63EBI-10172380,EBI-10244131
KCTD9Q7L2733EBI-10172380,EBI-4397613
LDOC1O957513EBI-10172380,EBI-740738
LMO1P258003EBI-10172380,EBI-8639312
MORN3Q6PF183EBI-10172380,EBI-9675802
NEK6Q9HC983EBI-10172380,EBI-740364
POLR1CO151603EBI-10172380,EBI-1055079
PPP1R16BQ96T493EBI-10172380,EBI-10293968
PRKAB2O437413EBI-10172380,EBI-1053424
SCAMP1O151263EBI-10172380,EBI-954338
TRIM23P364063EBI-10172380,EBI-740098
TRIM42A1L4B63EBI-10172380,EBI-10172216

Protein-protein interaction databases

BioGridi120252. 36 interactions.
IntActiQ5VWN6. 26 interactions.
MINTiMINT-7032141.
STRINGi9606.ENSP00000328426.

Structurei

3D structure databases

ProteinModelPortaliQ5VWN6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM208 family.Curated

Phylogenomic databases

eggNOGiENOG410II9C. Eukaryota.
ENOG410YF12. LUCA.
GeneTreeiENSGT00530000063735.
HOVERGENiHBG095571.
InParanoidiQ5VWN6.
OMAiEPQHFCQ.
OrthoDBiEOG70ZZMX.
PhylomeDBiQ5VWN6.
TreeFamiTF337844.

Family and domain databases

InterProiIPR022168. DUF3699.
IPR022188. DUF3715.
[Graphical view]
PfamiPF12480. DUF3699. 1 hit.
PF12509. DUF3715. 2 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q5VWN6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAPPAHKSIL ERSENVLMSP WKGKLIVQDR MLCDIALWST YGAMIPTQLP
60 70 80 90 100
QELDFKYVMK VSSLKKRLPE AAFRKQNYLE EKVCFQDLCF NLYEVELSNR
110 120 130 140 150
QGENIDKLTE CIKNKQLAII KCLEDRGFFI LLTSSALLSE PDFGGKQMGL
160 170 180 190 200
HGLHLFRSPL STGVKDLKVE DDISMKVIPI LSTLNCALLE TKKSLPEERI
210 220 230 240 250
HPNTLVKRHF QELYKADRSP SLSVAPQDRM KDPTFLGKLP SGFDLIPPAE
260 270 280 290 300
KCPSESLTQL NSYFSDPSAY ILEVSTALDL LAEHPQSPCV SDGICDAGFS
310 320 330 340 350
LVMTPDPEFL VSEAEVRKET ETKKDSEEML KAKKRVFPLS PASNLRVQPK
360 370 380 390 400
RKASMPHMVQ SKKVNLCRPF PKRTASRADN SSDSPTTLKL VKGQFPQKRK
410 420 430 440 450
RGAEVLTAQF VQKTKLDRKN QEAPISKDVP VPTNAKRARK QEKSPVKTVP
460 470 480 490 500
RAKPPVKKSP QKQRVNIVKG NENPRNRKQL QPVKGETASK LQSEISRGCQ
510 520 530 540 550
EDGISINSVQ PENTTAAHND LPENSIVNYD SQALNMLADL ALSSATSSTP
560 570 580 590 600
VSEARNLHCS SELPQNDVLL SKENSLRGTS DHEYHRGVKT QKGELLPNPS
610 620 630 640 650
SDRKSNSGSD LTVSQDEESL VPCSQAPAKA QSALTEEMLE SSDASQSSSV
660 670 680 690 700
SVEHSYALLL TEHSKKHLQE REILSPLFPR NGTKSPEAAT PVGKVMPFRH
710 720 730 740 750
QPGLLLQQKP PDDPVVKPKD RPPSARVKKS SCSRIVLSCD DSVKITFKCE
760 770 780 790 800
TEYAFSLDSK YTNNPLEKTV VRALHGPWNT DLPDNVEEVK LLLHMWVALF
810 820 830 840 850
YSNQNKIIRS SRKVVEHSNP AKYVSINSTL ESCELREIEE SLGLEKCSAD
860 870 880 890 900
SLLETNEISR AHAAEVSFRD PNCLLPFIKT PLTQGLELCV QNEQKKTFAR
910 920 930 940 950
ECDPDTQEDQ NFICSYNNEV TGEEAKQESL ETSNLVLSGI GSTQTNGPSV
960 970 980 990 1000
PSEEEIVQPL DSTRVASYSG TVTQATFTRT YDGPGSQPVI CQSSVYGTLE
1010 1020 1030 1040 1050
NKVDILDAAV QTKTGTLQDL IQHGSPINNE CHPSLERKDD NMGCAVINPE
1060 1070 1080 1090 1100
PITLTFEKNA HVPIQTEGVN TADERTTFKK ELIKQVSPAA SLRHPVSTSE
1110 1120 1130 1140 1150
NARTQGLRDI PSLVVAGQKG TKYLCASSVG GETLDKAVCS LQKETPLPVS
1160 1170 1180 1190 1200
LPSDKTMVME ALSLAKSSSH LSPSEEVRCT QDFLSQTQSL LGLSSEGLLE
1210 1220 1230 1240 1250
LTQVEVDSSS ASTTLGRQCS LNCISSGCHT SGDSLELRKN HKNGPNTENM
1260 1270 1280 1290 1300
NLEAFDSVFI KQTSLSVSRE VSLELSEEDS DIDLALTISP PTSPREEMPA
1310 1320 1330 1340 1350
GEIEQFEEAP FSNLELQDVA EEIGEPEEVA LTESREVSSA DNVSVYPSVS
1360 1370 1380 1390 1400
EEPVENKERK GDNLQPVTLI LSKENCTLEI AEEINVTSDF PFDSVIEEVS
1410 1420 1430 1440 1450
PASSPEPPVP VKETRPYQAV TPCILKLHGT QCEKSNQISQ CESEDLGITE
1460 1470 1480 1490 1500
KENVFVGPTH PVGQDNFTQV QQMQVSAEMP LILTDHPGRT GRPTLPGKVT
1510 1520 1530 1540 1550
EEIVSSEHDE GLSFSGKVQC YGRELNQPAS AAKCTGDFSP SPEKLVKSGN
1560 1570 1580 1590 1600
PLQPVSIENR NLDLKHLVLE SSEPPFGPRN VIENKSLSDT LVSTTAPSGI
1610 1620 1630 1640 1650
VNVSVKQQTS PKSSQNHLFP GDLKTDEGIY LQVKSLTAAS VDGAYSTQGC
1660 1670 1680 1690 1700
MCSVVPTLCS SSDNATLTHY VRPINAEPVF QAQEIPAGRM ASLLKNGEPE
1710 1720 1730 1740 1750
AELHKETTGP GTAGPQSNTT SSLKGERKAI HTLQDVSTCE TKELLNVGVS
1760 1770 1780 1790 1800
SLCAGPYQNT ADTKENLSKE PLASFVSESF DTSVCGIATE HVEIENSGEG
1810 1820 1830 1840 1850
LRAEAGSETL GRDGEVGVNS DMHYELSGDS DLDLLGDCRN PRLDLEDSYT
1860 1870 1880 1890 1900
LRGSYTRKKD VPTDGYESSL NFHNNNQEDW GCSSWVPGME TSLPPGHWTA
1910 1920 1930 1940 1950
AVKKEEKCVP PYVQIRDLHG ILRTYANFSI TKELKDTMRT SHGLRRHPSF
1960 1970 1980 1990 2000
SANCGLPSSW TSTWQVADDL TQNTLDLEYL RFAHKLKQTI KNGDSQHSAS
2010 2020 2030 2040 2050
SANVFPKESP TQISIGAFPS TKISEAPFLH PAPRSRSPLL VTVVESDPRP
2060 2070 2080 2090 2100
QGQPRRGYTA SSLDSSSSWR ERCSHNRDLR NSQRNHTVSF HLNKLKYNST
2110 2120 2130 2140 2150
VKESRNDISL ILNEYAEFNK VMKNSNQFIF QDKELNDVSG EATAQEMYLP
2160 2170 2180 2190 2200
FPGRSASYED IIIDVCTNLH VKLRSVVKEA CKSTFLFYLV ETEDKSFFVR
2210 2220 2230 2240 2250
TKNLLRKGGH TEIEPQHFCQ AFHRENDTLI IIIRNEDISS HLHQIPSLLK
2260 2270 2280 2290 2300
LKHFPSVIFA GVDSPGDVLD HTYQELFRAG GFVISDDKIL EAVTLVQLKE
2310 2320 2330 2340 2350
IIKILEKLNG NGRWKWLLHY RENKKLKEDE RVDSTAHKKN IMLKSFQSAN
2360 2370 2380 2390 2400
IIELLHYHQC DSRSSTKAEI LKCLLNLQIQ HIDARFAVLL TDKPTIPREV
2410 2420 2430
FENSGILVTD VNNFIENIEK IAAPFRSSYW
Length:2,430
Mass (Da):268,843
Last modified:December 7, 2004 - v1
Checksum:i8A6A94D318280DCE
GO
Isoform 2 (identifier: Q5VWN6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     333-1137: Missing.

Show »
Length:1,625
Mass (Da):180,380
Checksum:i633F6CEAFB1585AB
GO

Sequence cautioni

The sequence BAA91115.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB14336.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB14993.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC87251.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1885 – 18851W → R in BAA91115 (PubMed:14702039).Curated
Sequence conflicti2043 – 20431V → A in BAA91115 (PubMed:14702039).Curated
Sequence conflicti2065 – 20651S → I in BAA91115 (PubMed:14702039).Curated
Sequence conflicti2359 – 23591Q → R in BAB14993 (PubMed:14702039).Curated
Sequence conflicti2384 – 23841A → T in BAB14993 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti499 – 4991C → G.
Corresponds to variant rs2254067 [ dbSNP | Ensembl ].
VAR_050848
Natural varianti630 – 6301A → D.
Corresponds to variant rs4748636 [ dbSNP | Ensembl ].
VAR_050849
Natural varianti724 – 7241S → Y.
Corresponds to variant rs56856085 [ dbSNP | Ensembl ].
VAR_061601
Natural varianti807 – 8071I → V.
Corresponds to variant rs45575338 [ dbSNP | Ensembl ].
VAR_061602
Natural varianti1075 – 10751R → P.1 Publication
Corresponds to variant rs2797491 [ dbSNP | Ensembl ].
VAR_034838
Natural varianti1206 – 12061V → M.
Corresponds to variant rs3814196 [ dbSNP | Ensembl ].
VAR_050850
Natural varianti1578 – 15781P → S.
Corresponds to variant rs17143175 [ dbSNP | Ensembl ].
VAR_050851
Natural varianti1679 – 16791V → A.3 Publications
Corresponds to variant rs2669142 [ dbSNP | Ensembl ].
VAR_034839
Natural varianti1782 – 17821T → I.
Corresponds to variant rs11593253 [ dbSNP | Ensembl ].
VAR_050852
Natural varianti2288 – 22881K → R.
Corresponds to variant rs2275774 [ dbSNP | Ensembl ].
VAR_050853
Natural varianti2404 – 24041S → N.3 Publications
Corresponds to variant rs2797501 [ dbSNP | Ensembl ].
VAR_034840

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei333 – 1137805Missing in isoform 2. 1 PublicationVSP_027733Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365356, AL596094 Genomic DNA. Translation: CAH72616.1.
AL365356, AL596094 Genomic DNA. Translation: CAH72617.1.
AL596094, AL365356 Genomic DNA. Translation: CAI13368.1.
AL596094, AL365356 Genomic DNA. Translation: CAI13367.1.
AB095927 mRNA. Translation: BAC23103.1.
AK000367 mRNA. Translation: BAA91115.1. Different initiation.
AK022966 mRNA. Translation: BAB14336.1. Different initiation.
AK024762 mRNA. Translation: BAB14993.1. Different initiation.
AK027014 mRNA. Translation: BAB15627.1.
AK128051 mRNA. Translation: BAC87251.1. Different initiation.
BC001759 mRNA. Translation: AAH01759.2.
BC110339 mRNA. Translation: AAI10340.1.
CCDSiCCDS41485.1. [Q5VWN6-1]
RefSeqiNP_060252.4. NM_017782.4.
XP_005252532.1. XM_005252475.2. [Q5VWN6-1]
XP_005252535.1. XM_005252478.3. [Q5VWN6-1]
XP_005252537.1. XM_005252480.3. [Q5VWN6-1]
XP_005252538.1. XM_005252481.3. [Q5VWN6-1]
XP_005252539.1. XM_005252482.1. [Q5VWN6-1]
XP_011517827.1. XM_011519525.1. [Q5VWN6-1]
UniGeneiHs.610717.
Hs.694576.

Genome annotation databases

EnsembliENST00000328090; ENSP00000328426; ENSG00000108021. [Q5VWN6-1]
GeneIDi54906.
KEGGihsa:54906.
UCSCiuc001iij.3. human. [Q5VWN6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365356, AL596094 Genomic DNA. Translation: CAH72616.1.
AL365356, AL596094 Genomic DNA. Translation: CAH72617.1.
AL596094, AL365356 Genomic DNA. Translation: CAI13368.1.
AL596094, AL365356 Genomic DNA. Translation: CAI13367.1.
AB095927 mRNA. Translation: BAC23103.1.
AK000367 mRNA. Translation: BAA91115.1. Different initiation.
AK022966 mRNA. Translation: BAB14336.1. Different initiation.
AK024762 mRNA. Translation: BAB14993.1. Different initiation.
AK027014 mRNA. Translation: BAB15627.1.
AK128051 mRNA. Translation: BAC87251.1. Different initiation.
BC001759 mRNA. Translation: AAH01759.2.
BC110339 mRNA. Translation: AAI10340.1.
CCDSiCCDS41485.1. [Q5VWN6-1]
RefSeqiNP_060252.4. NM_017782.4.
XP_005252532.1. XM_005252475.2. [Q5VWN6-1]
XP_005252535.1. XM_005252478.3. [Q5VWN6-1]
XP_005252537.1. XM_005252480.3. [Q5VWN6-1]
XP_005252538.1. XM_005252481.3. [Q5VWN6-1]
XP_005252539.1. XM_005252482.1. [Q5VWN6-1]
XP_011517827.1. XM_011519525.1. [Q5VWN6-1]
UniGeneiHs.610717.
Hs.694576.

3D structure databases

ProteinModelPortaliQ5VWN6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120252. 36 interactions.
IntActiQ5VWN6. 26 interactions.
MINTiMINT-7032141.
STRINGi9606.ENSP00000328426.

PTM databases

iPTMnetiQ5VWN6.
PhosphoSiteiQ5VWN6.

Polymorphism and mutation databases

BioMutaiFAM208B.
DMDMi74747424.

Proteomic databases

EPDiQ5VWN6.
MaxQBiQ5VWN6.
PaxDbiQ5VWN6.
PRIDEiQ5VWN6.

Protocols and materials databases

DNASUi54906.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000328090; ENSP00000328426; ENSG00000108021. [Q5VWN6-1]
GeneIDi54906.
KEGGihsa:54906.
UCSCiuc001iij.3. human. [Q5VWN6-1]

Organism-specific databases

CTDi54906.
GeneCardsiFAM208B.
H-InvDBHIX0008613.
HGNCiHGNC:23484. FAM208B.
HPAiHPA038042.
HPA038043.
HPA061547.
neXtProtiNX_Q5VWN6.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410II9C. Eukaryota.
ENOG410YF12. LUCA.
GeneTreeiENSGT00530000063735.
HOVERGENiHBG095571.
InParanoidiQ5VWN6.
OMAiEPQHFCQ.
OrthoDBiEOG70ZZMX.
PhylomeDBiQ5VWN6.
TreeFamiTF337844.

Miscellaneous databases

ChiTaRSiFAM208B. human.
GenomeRNAii54906.
PROiQ5VWN6.

Gene expression databases

BgeeiQ5VWN6.
CleanExiHS_C10orf18.
ExpressionAtlasiQ5VWN6. baseline and differential.
GenevisibleiQ5VWN6. HS.

Family and domain databases

InterProiIPR022168. DUF3699.
IPR022188. DUF3715.
[Graphical view]
PfamiPF12480. DUF3699. 1 hit.
PF12509. DUF3715. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The nucleotide sequence of a long cDNA clone isolated from human."
    Nagase T., Kikuno R., Ohara O.
    Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 259-2430 (ISOFORM 2), VARIANTS PRO-1075; ALA-1679 AND ASN-2404.
    Tissue: Brain.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 701-2430, VARIANTS ALA-1679 AND ASN-2404.
    Tissue: Testis.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1662-2430, VARIANTS ALA-1679 AND ASN-2404.
    Tissue: Blood and Eye.
  5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-384 AND SER-2037, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19; SER-1087 AND SER-2009, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1025, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiF208B_HUMAN
AccessioniPrimary (citable) accession number: Q5VWN6
Secondary accession number(s): Q2YD91
, Q5VWN5, Q6ZRQ8, Q8IVG4, Q9BUZ7, Q9H5J9, Q9H7A4, Q9H996, Q9NXA1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: December 7, 2004
Last modified: June 8, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.