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Protein
Submitted name:

Transcription factor 7-like 2

Gene

TCF7L2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor 7-like 2Imported
Gene namesi
Name:TCF7L2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000148737.15
HGNCiHGNC:11641 TCF7L2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000148737

PTM / Processingi

Proteomic databases

PeptideAtlasiQ5VVR8
PRIDEiQ5VVR8

Expressioni

Gene expression databases

BgeeiENSG00000148737
ExpressionAtlasiQ5VVR8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5VVR8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 76CTNNB1_bindingInterPro annotationAdd BLAST75

Phylogenomic databases

eggNOGiKOG3248 Eukaryota
ENOG41109RU LUCA
GeneTreeiENSGT00390000009964
HOGENOMiHOG000116032
HOVERGENiHBG000419

Family and domain databases

InterProiView protein in InterPro
IPR013558 CTNNB1-bd_N
IPR024940 TCF/LEF
PANTHERiPTHR10373 PTHR10373, 1 hit
PfamiView protein in Pfam
PF08347 CTNNB1_binding, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5VVR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNKVPVVQH PHHVHPLTPL ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP
60 70 80 90 100
PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ QGQPVYPITT GGFRHPYPTA

LTVNASMS
Length:108
Mass (Da):11,731
Last modified:October 5, 2016 - v2
Checksum:i669776E126FA7B99
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei108Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135792 Genomic DNA No translation available.
AL158212 Genomic DNA No translation available.
AL445486 Genomic DNA No translation available.
AL451084 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000349937; ENSP00000298692; ENSG00000148737
UCSCiuc057wbb.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5VVR8_HUMAN
AccessioniPrimary (citable) accession number: Q5VVR8
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 89 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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