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Protein
Submitted name:

cDNA FLJ50648, highly similar to Voltage-dependent L-type calcium channel subunit beta-2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50648, highly similar to Voltage-dependent L-type calcium channel subunit beta-2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000165995.18.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA88.

PTM / Processingi

Proteomic databases

MaxQBiQ5VVH1.
PaxDbiQ5VVH1.
PRIDEiQ5VVH1.

Expressioni

Gene expression databases

BgeeiENSG00000165995.
ExpressionAtlasiQ5VVH1. baseline and differential.
GenevisibleiQ5VVH1. HS.

Structurei

3D structure databases

ProteinModelPortaliQ5VVH1.
SMRiQ5VVH1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 127SH3InterPro annotationAdd BLAST62

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3812. Eukaryota.
ENOG410XRDI. LUCA.
HOGENOMiHOG000230979.
HOVERGENiHBG050765.

Family and domain databases

CDDicd12040. SH3_CACNB2. 1 hit.
InterProiView protein in InterPro
IPR035605. CACNB2_SH3.
IPR008145. GK/Ca_channel_bsu.
IPR027417. P-loop_NTPase.
IPR036028. SH3-like_dom_sf.
IPR001452. SH3_domain.
IPR005444. VDCC_L_b2su.
IPR000584. VDCC_L_bsu.
PANTHERiPTHR11824. PTHR11824. 1 hit.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
PF12052. VGCC_beta4Aa_N. 1 hit.
PRINTSiPR01626. LCACHANNELB.
PR01628. LCACHANNELB2.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF50044. SSF50044. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5VVH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKATWIRLLK RAKGGRLKNS DICGSADSYT SRPSDSDVSL EEDREAVRRE
60 70 80 90 100
AERQAQAQLE KAKTKPVAFA VRTNVSYSAA HEDDVPVPGM AISFEAKDFL
110 120 130 140 150
HVKEKFNNDW WIGRLVKEGC EIGFIPSPVK LENMRLQHEQ RAKQGKFYSS
160 170 180 190 200
KSGGNSSSSL GDIVPSSRKS TPPSSAIDID ATGLDAEEND IPANHRSPKP
210 220 230 240 250
SANSVTSPHS KEKRMPFFKK TEHTPPYDVV PSMRPVVLVG PSLKGYEVTD
260 270 280 290 300
MMQKALFDFL KHRFEGRISI TRVTADISLA KRSVLNNPSK HAIIERSNTR
310 320 330 340 350
SSLAEVQSEI ERIFELARTL QLVVLDADTI NHPAQLSKTS LAPIIVYVKI
360 370 380 390 400
SSPKVLQRLI KSRGKSQAKH LNVQMVAADK LAQCPPELFD VILDENQLED
410 420 430 440 450
ACEHLADYLE AYWKATHPPS SSLPNPLLSR TLATSSLPLS PTLASNSQGS
460 470 480 490 500
QGDQRTDRSA PIRSASQAEE EPSVEPVKKS QHRSSSSAPH HNHRSGTSRG
510 520 530 540 550
LSRQETFDSE TQESRDSAYV EPKEDYSHDH VDHYASHRDH NHRDETHGSS
560 570 580 590 600
DHRHRESRHR SRDVDREQDH NECNKQRSRH KSKDRYCEKD GEVISKKRNE
610
AGEWNRDVYI RQ
Length:612
Mass (Da):68,838
Last modified:December 7, 2004 - v1
Checksum:i1D60077179676927
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK299873 mRNA. Translation: BAH13158.1.
RefSeqiNP_963864.1. NM_201570.2.
UniGeneiHs.59093.

Genome annotation databases

GeneIDi783.
UCSCiuc001iqa.3. human.

Similar proteinsi

Entry informationi

Entry nameiQ5VVH1_HUMAN
AccessioniPrimary (citable) accession number: Q5VVH1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: November 22, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.