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Protein

Transmembrane protein 244

Gene

TMEM244

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 244
Gene namesi
Name:TMEM244
Synonyms:C6orf191
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000203756.7.
HGNCiHGNC:21571. TMEM244.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalSequence analysisAdd BLAST21
Transmembranei65 – 85HelicalSequence analysisAdd BLAST21
Transmembranei93 – 113HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000203756.
PharmGKBiPA134909151.

Polymorphism and mutation databases

BioMutaiTMEM244.
DMDMi74747217.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002384671 – 128Transmembrane protein 244Add BLAST128

Proteomic databases

PaxDbiQ5VVB8.
PeptideAtlasiQ5VVB8.
PRIDEiQ5VVB8.
TopDownProteomicsiQ5VVB8.

Expressioni

Gene expression databases

BgeeiENSG00000203756.
CleanExiHS_C6orf191.

Organism-specific databases

HPAiHPA045247.

Structurei

3D structure databases

ProteinModelPortaliQ5VVB8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J003. Eukaryota.
ENOG410YMZT. LUCA.
GeneTreeiENSGT00390000007791.
HOGENOMiHOG000007700.
HOVERGENiHBG057717.
InParanoidiQ5VVB8.
OMAiVVEEWVW.
OrthoDBiEOG091G0M6R.
PhylomeDBiQ5VVB8.
TreeFamiTF340485.

Family and domain databases

InterProiView protein in InterPro
IPR019185. Integral_membrane_SYS1-rel.
PANTHERiPTHR12952. PTHR12952. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5VVB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALQVRVAPS KVVLQKFLLC VILFYTVYYV SLSMGCVMFE VHELNVLAPF
60 70 80 90 100
DFKTNPSWLN INYKVLLVST EVTYFVCGLF FVPVVEEWVW DYAISVTILH
110 120
VAITSTVMLE FPLTSHWWAA LGISKLLV
Length:128
Mass (Da):14,657
Last modified:December 7, 2004 - v1
Checksum:i9AB7F28C72185C38
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03368160N → I. Corresponds to variant dbSNP:rs7760577Ensembl.1
Natural variantiVAR_02654980F → L. Corresponds to variant dbSNP:rs4629709Ensembl.1
Natural variantiVAR_02655086E → G. Corresponds to variant dbSNP:rs9492393Ensembl.1
Natural variantiVAR_026551111F → V. Corresponds to variant dbSNP:rs7776426Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL451046 Genomic DNA. No translation available.
CCDSiCCDS34536.1.
RefSeqiNP_001010876.1. NM_001010876.1.
UniGeneiHs.448372.

Genome annotation databases

EnsembliENST00000368143; ENSP00000357125; ENSG00000203756.
ENST00000438392; ENSP00000403755; ENSG00000203756.
GeneIDi253582.
KEGGihsa:253582.
UCSCiuc003qbs.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiTM244_HUMAN
AccessioniPrimary (citable) accession number: Q5VVB8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: December 7, 2004
Last modified: September 27, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations