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Q5VV67

- PPRC1_HUMAN

UniProt

Q5VV67 - PPRC1_HUMAN

Protein

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

Gene

PPRC1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 1 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes.2 Publications

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. poly(A) RNA binding Source: UniProtKB

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    ReactomeiREACT_200608. Transcriptional activation of mitochondrial biogenesis.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Alternative name(s):
    PGC-1-related coactivator
    Short name:
    PRC
    Gene namesi
    Name:PPRC1
    Synonyms:KIAA0595
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:30025. PPRC1.

    Subcellular locationi

    Nucleus 1 Publication
    Note: Colocalizes with NRF1.By similarity

    GO - Cellular componenti

    1. nucleus Source: HPA

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134886297.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 16641664Peroxisome proliferator-activated receptor gamma coactivator-related protein 1PRO_0000296666Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei536 – 5361Phosphoserine1 Publication
    Modified residuei1411 – 14111Phosphoserine1 Publication
    Modified residuei1413 – 14131Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ5VV67.
    PaxDbiQ5VV67.
    PRIDEiQ5VV67.

    PTM databases

    PhosphoSiteiQ5VV67.

    Expressioni

    Tissue specificityi

    Strongly expressed in heart and skeletal muscle, moderately in lung, placenta, intestine, liver, kidney, spleen, thymus, colon and brain. Also expressed in several oncocytic thyroid tumors.2 Publications

    Inductioni

    Up-regulated by serum (at protein level).1 Publication

    Gene expression databases

    ArrayExpressiQ5VV67.
    BgeeiQ5VV67.
    CleanExiHS_PPRC1.
    GenevestigatoriQ5VV67.

    Organism-specific databases

    HPAiHPA038511.

    Interactioni

    Subunit structurei

    Interacts with CREB1 and NRF1.2 Publications

    Protein-protein interaction databases

    BioGridi116713. 4 interactions.
    IntActiQ5VV67. 2 interactions.
    STRINGi9606.ENSP00000278070.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5VV67.
    SMRiQ5VV67. Positions 1543-1599.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1543 – 161977RRMPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni433 – 46735Necessary for interaction with CREB1 and NRF1 and for transcriptional coactivationAdd
    BLAST
    Regioni1379 – 145072Necessary for interaction with CREB1 and NRF1Add
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi772 – 1137366Pro-richAdd
    BLAST
    Compositional biasi1400 – 1543144Arg-richAdd
    BLAST
    Compositional biasi1411 – 1523113Ser-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG69689.
    HOVERGENiHBG103282.
    InParanoidiQ5VV67.
    KOiK17963.
    OMAiFCKRSYS.
    OrthoDBiEOG7S4X5H.
    PhylomeDBiQ5VV67.
    TreeFamiTF343068.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view]
    PfamiPF00076. RRM_1. 1 hit.
    [Graphical view]
    SMARTiSM00360. RRM. 1 hit.
    [Graphical view]
    PROSITEiPS50102. RRM. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q5VV67-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAARRGRRDG VAPPPSGGPG PDPGGGARGS GWGSRSQAPY GTLGAVSGGE     50
    QVLLHEEAGD SGFVSLSRLG PSLRDKDLEM EELMLQDETL LGTMQSYMDA 100
    SLISLIEDFG SLGESRLSLE DQNEVSLLTA LTEILDNADS ENLSPFDSIP 150
    DSELLVSPRE GSSLHKLLTL SRTPPERDLI TPVDPLGPST GSSRGSGVEM 200
    SLPDPSWDFS PPSFLETSSP KLPSWRPPRS RPRWGQSPPP QQRSDGEEEE 250
    EVASFSGQIL AGELDNCVSS IPDFPMHLAC PEEEDKATAA EMAVPAAGDE 300
    SISSLSELVR AMHPYCLPNL THLASLEDEL QEQPDDLTLP EGCVVLEIVG 350
    QAATAGDDLE IPVVVRQVSP GPRPVLLDDS LETSSALQLL MPTLESETEA 400
    AVPKVTLCSE KEGLSLNSEE KLDSACLLKP REVVEPVVPK EPQNPPANAA 450
    PGSQRARKGR KKKSKEQPAA CVEGYARRLR SSSRGQSTVG TEVTSQVDNL 500
    QKQPQEELQK ESGPLQGKGK PRAWARAWAA ALENSSPKNL ERSAGQSSPA 550
    KEGPLDLYPK LADTIQTNPI PTHLSLVDSA QASPMPVDSV EADPTAVGPV 600
    LAGPVPVDPG LVDLASTSSE LVEPLPAEPV LINPVLADSA AVDPAVVPIS 650
    DNLPPVDAVP SGPAPVDLAL VDPVPNDLTP VDPVLVKSRP TDPRRGAVSS 700
    ALGGSAPQLL VESESLDPPK TIIPEVKEVV DSLKIESGTS ATTHEARPRP 750
    LSLSEYRRRR QQRQAETEER SPQPPTGKWP SLPETPTGLA DIPCLVIPPA 800
    PAKKTALQRS PETPLEICLV PVGPSPASPS PEPPVSKPVA SSPTEQVPSQ 850
    EMPLLARPSP PVQSVSPAVP TPPSMSAALP FPAGGLGMPP SLPPPPLQPP 900
    SLPLSMGPVL PDPFTHYAPL PSWPCYPHVS PSGYPCLPPP PTVPLVSGTP 950
    GAYAVPPTCS VPWAPPPAPV SPYSSTCTYG PLGWGPGPQH APFWSTVPPP 1000
    PLPPASIGRA VPQPKMESRG TPAGPPENVL PLSMAPPLSL GLPGHGAPQT 1050
    EPTKVEVKPV PASPHPKHKV SALVQSPQMK ALACVSAEGV TVEEPASERL 1100
    KPETQETRPR EKPPLPATKA VPTPRQSTVP KLPAVHPARL RKLSFLPTPR 1150
    TQGSEDVVQA FISEIGIEAS DLSSLLEQFE KSEAKKECPP PAPADSLAVG 1200
    NSGGVDIPQE KRPLDRLQAP ELANVAGLTP PATPPHQLWK PLAAVSLLAK 1250
    AKSPKSTAQE GTLKPEGVTE AKHPAAVRLQ EGVHGPSRVH VGSGDHDYCV 1300
    RSRTPPKKMP ALVIPEVGSR WNVKRHQDIT IKPVLSLGPA APPPPCIAAS 1350
    REPLDHRTSS EQADPSAPCL APSSLLSPEA SPCRNDMNTR TPPEPSAKQR 1400
    SMRCYRKACR SASPSSQGWQ GRRGRNSRSV SSGSNRTSEA SSSSSSSSSS 1450
    SRSRSRSLSP PHKRWRRSSC SSSGRSRRCS SSSSSSSSSS SSSSSSSSSR 1500
    SRSRSPSPRR RSDRRRRYSS YRSHDHYQRQ RVLQKERAIE ERRVVFIGKI 1550
    PGRMTRSELK QRFSVFGEIE ECTIHFRVQG DNYGFVTYRY AEEAFAAIES 1600
    GHKLRQADEQ PFDLCFGGRR QFCKRSYSDL DSNREDFDPA PVKSKFDSLD 1650
    FDTLLKQAQK NLRR 1664
    Length:1,664
    Mass (Da):177,544
    Last modified:December 7, 2004 - v1
    Checksum:i01D4138F80C620E8
    GO
    Isoform 2 (identifier: Q5VV67-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-120: Missing.
         121-147: DQNEVSLLTALTEILDNADSENLSPFD → MRHCWGPCRATWMPPLSPSLRILGALE
         1518-1519: Missing.

    Show »
    Length:1,542
    Mass (Da):164,965
    Checksum:i9B120057AA1A0CA4
    GO

    Sequence cautioni

    The sequence AAH02561.2 differs from that shown. Reason: Frameshift at position 1643.
    The sequence BAA25521.2 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti33 – 331G → R in AAK11573. (PubMed:11340167)Curated
    Sequence conflicti69 – 691L → Q in AAK11573. (PubMed:11340167)Curated
    Sequence conflicti122 – 1221Q → H in AAK11573. (PubMed:11340167)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti536 – 5361S → G.
    Corresponds to variant rs17114388 [ dbSNP | Ensembl ].
    VAR_034633
    Natural varianti834 – 8341P → R.1 Publication
    Corresponds to variant rs17855877 [ dbSNP | Ensembl ].
    VAR_034634

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 120120Missing in isoform 2. 1 PublicationVSP_027229Add
    BLAST
    Alternative sequencei121 – 14727DQNEV…LSPFD → MRHCWGPCRATWMPPLSPSL RILGALE in isoform 2. 1 PublicationVSP_027230Add
    BLAST
    Alternative sequencei1518 – 15192Missing in isoform 2. 1 PublicationVSP_027231

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF325193 mRNA. Translation: AAK11573.1.
    AB011167 mRNA. Translation: BAA25521.2. Different initiation.
    AL500527 Genomic DNA. Translation: CAH72218.1.
    AL500527 Genomic DNA. Translation: CAH72219.1.
    BC002561 mRNA. Translation: AAH02561.2. Frameshift.
    BC063806 mRNA. Translation: AAH63806.1.
    BC063829 mRNA. Translation: AAH63829.1.
    CCDSiCCDS7529.1. [Q5VV67-1]
    PIRiT00273.
    RefSeqiNP_001275656.1. NM_001288727.1.
    NP_001275657.1. NM_001288728.1. [Q5VV67-2]
    NP_055877.3. NM_015062.4. [Q5VV67-1]
    UniGeneiHs.533551.

    Genome annotation databases

    EnsembliENST00000278070; ENSP00000278070; ENSG00000148840. [Q5VV67-1]
    GeneIDi23082.
    KEGGihsa:23082.
    UCSCiuc001kum.3. human. [Q5VV67-1]
    uc001kun.3. human. [Q5VV67-2]

    Polymorphism databases

    DMDMi74756889.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF325193 mRNA. Translation: AAK11573.1 .
    AB011167 mRNA. Translation: BAA25521.2 . Different initiation.
    AL500527 Genomic DNA. Translation: CAH72218.1 .
    AL500527 Genomic DNA. Translation: CAH72219.1 .
    BC002561 mRNA. Translation: AAH02561.2 . Frameshift.
    BC063806 mRNA. Translation: AAH63806.1 .
    BC063829 mRNA. Translation: AAH63829.1 .
    CCDSi CCDS7529.1. [Q5VV67-1 ]
    PIRi T00273.
    RefSeqi NP_001275656.1. NM_001288727.1.
    NP_001275657.1. NM_001288728.1. [Q5VV67-2 ]
    NP_055877.3. NM_015062.4. [Q5VV67-1 ]
    UniGenei Hs.533551.

    3D structure databases

    ProteinModelPortali Q5VV67.
    SMRi Q5VV67. Positions 1543-1599.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 116713. 4 interactions.
    IntActi Q5VV67. 2 interactions.
    STRINGi 9606.ENSP00000278070.

    PTM databases

    PhosphoSitei Q5VV67.

    Polymorphism databases

    DMDMi 74756889.

    Proteomic databases

    MaxQBi Q5VV67.
    PaxDbi Q5VV67.
    PRIDEi Q5VV67.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000278070 ; ENSP00000278070 ; ENSG00000148840 . [Q5VV67-1 ]
    GeneIDi 23082.
    KEGGi hsa:23082.
    UCSCi uc001kum.3. human. [Q5VV67-1 ]
    uc001kun.3. human. [Q5VV67-2 ]

    Organism-specific databases

    CTDi 23082.
    GeneCardsi GC10P103882.
    HGNCi HGNC:30025. PPRC1.
    HPAi HPA038511.
    neXtProti NX_Q5VV67.
    PharmGKBi PA134886297.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG69689.
    HOVERGENi HBG103282.
    InParanoidi Q5VV67.
    KOi K17963.
    OMAi FCKRSYS.
    OrthoDBi EOG7S4X5H.
    PhylomeDBi Q5VV67.
    TreeFami TF343068.

    Enzyme and pathway databases

    Reactomei REACT_200608. Transcriptional activation of mitochondrial biogenesis.

    Miscellaneous databases

    GeneWikii PPRC1.
    GenomeRNAii 23082.
    NextBioi 44209.
    PROi Q5VV67.

    Gene expression databases

    ArrayExpressi Q5VV67.
    Bgeei Q5VV67.
    CleanExi HS_PPRC1.
    Genevestigatori Q5VV67.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view ]
    Pfami PF00076. RRM_1. 1 hit.
    [Graphical view ]
    SMARTi SM00360. RRM. 1 hit.
    [Graphical view ]
    PROSITEi PS50102. RRM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells."
      Andersson U., Scarpulla R.C.
      Mol. Cell. Biol. 21:3738-3749(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INTERACTION WITH NRF1, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    2. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Nagase T., Ishikawa K., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
      DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
      DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION.
    4. "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
      , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
      Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 998-1664 (ISOFORM 1), VARIANT ARG-834.
      Tissue: Placenta and Uterus.
    6. Cited for: TISSUE SPECIFICITY.
    7. "PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth."
      Vercauteren K., Pasko R.A., Gleyzer N., Marino V.M., Scarpulla R.C.
      Mol. Cell. Biol. 26:7409-7419(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH CREB1 AND NRF1, INDUCTION.
    8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-536, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1411 AND SER-1413, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPPRC1_HUMAN
    AccessioniPrimary (citable) accession number: Q5VV67
    Secondary accession number(s): Q5VV66
    , Q6P3U5, Q6P3W1, Q76N31, Q9BUJ3, Q9BZE5, Q9Y4E0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 24, 2007
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 97 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 10
      Human chromosome 10: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3