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Protein

Ankyrin repeat domain-containing protein 20A3

Gene

ANKRD20A3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 20A3
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:31981. ANKRD20A3.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA143485301.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 823823Ankyrin repeat domain-containing protein 20A3PRO_0000240836Add
BLAST

Proteomic databases

MaxQBiQ5VUR7.
PaxDbiQ5VUR7.
PRIDEiQ5VUR7.

PTM databases

PhosphoSiteiQ5VUR7.

Expressioni

Gene expression databases

BgeeiQ5VUR7.
GenevestigatoriQ5VUR7.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000366697.

Structurei

3D structure databases

ProteinModelPortaliQ5VUR7.
SMRiQ5VUR7. Positions 19-297.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati66 – 9530ANK 1Add
BLAST
Repeati99 – 12830ANK 2Add
BLAST
Repeati132 – 16130ANK 3Add
BLAST
Repeati165 – 19430ANK 4Add
BLAST
Repeati198 – 22730ANK 5Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili431 – 48050Sequence AnalysisAdd
BLAST
Coiled coili571 – 724154Sequence AnalysisAdd
BLAST
Coiled coili776 – 80530Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 5 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

eggNOGiCOG0666.
GeneTreeiENSGT00560000076605.
HOGENOMiHOG000230851.
HOVERGENiHBG079958.
InParanoidiQ5VUR7.
OMAiCNCVEER.
OrthoDBiEOG7N63KX.
PhylomeDBiQ5VUR7.
TreeFamiTF333496.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VUR7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLFGFGSRR GQTAQGSIDH VYTGSGYRIR DSELQKIHRA AVKGDAAEVE
60 70 80 90 100
RCLARRSGDL DALDKQHRTA LHLACASGHV QVVTLLVNRK CQIDVCDKEN
110 120 130 140 150
RTPLIQAVHC QEEACAVILL EHGANPNLKD IYGNTALHYA VYSESTSLAE
160 170 180 190 200
KLLSHGAHIE ALDKDNNTPL LFAIICKKEK MVEFLLKRKA SSHAVDRLRR
210 220 230 240 250
SALMLAVYYD SPGIVNILLK QNIDVFAQDM CGRDAEDYAI SHHLTKIQQQ
260 270 280 290 300
ILEHKKKILK KEKSDVGSSD ESAVSIFHEL RVDSLPASDD KDLNVATKQC
310 320 330 340 350
VPEKVSEPLP GSSHEKGNRI VNGQGEGPPA KHPSLKPSTE VEDPAVKGAV
360 370 380 390 400
QRKNVQTLRA EQALPVASEE EQERHERSEK KQPQVKEGNN TNKSEKIQLS
410 420 430 440 450
ENICDSTSSA AAGRLTQQRK IGKTYPQQFP KKLKEEHDRC TLKQENEEKT
460 470 480 490 500
NVNMLYKKNR EELERKEKQY KKEVEAKQLE PTVQSLEMKS KTARNTPNRD
510 520 530 540 550
FHNHEEMKGL MDENCILKAD IAILRQEICT MKNDNLEKEN KYLKDIKIVK
560 570 580 590 600
ETNAALEKYI KLNEEMITET AFRYQQELNY LKAENTRLNA ELLKEKESKK
610 620 630 640 650
RLEADIESYQ SRLAAAISKH SESVKTERNL KLALERTRDV SVQVEMSSAI
660 670 680 690 700
SKVKDENEFL TEQLSETQIK FNALKDKFRK TRDSLRKKSL ALETVQNDLS
710 720 730 740 750
QTQQQTQEMK EMYQNAEAKV NNSTGKWNCV EERICHLQRE NAWLVQQLDD
760 770 780 790 800
VHQKEDHKEI VTNIQRGFIE SGKKDLVLEE KSKKLMNECD HLKESLFQYE
810 820
REKTEGVVSI KEDKYFQTSR KTI
Length:823
Mass (Da):94,108
Last modified:December 7, 2004 - v1
Checksum:iCC0ED7895CA092E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513478 Genomic DNA. Translation: CAH72532.1.
CCDSiCCDS35029.1.
RefSeqiNP_001012419.1. NM_001012419.2.
UniGeneiHs.632663.

Genome annotation databases

EnsembliENST00000611388; ENSP00000482325; ENSG00000276203.
GeneIDi441425.
KEGGihsa:441425.
UCSCiuc004acd.3. human.

Polymorphism databases

DMDMi74747147.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513478 Genomic DNA. Translation: CAH72532.1.
CCDSiCCDS35029.1.
RefSeqiNP_001012419.1. NM_001012419.2.
UniGeneiHs.632663.

3D structure databases

ProteinModelPortaliQ5VUR7.
SMRiQ5VUR7. Positions 19-297.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000366697.

PTM databases

PhosphoSiteiQ5VUR7.

Polymorphism databases

DMDMi74747147.

Proteomic databases

MaxQBiQ5VUR7.
PaxDbiQ5VUR7.
PRIDEiQ5VUR7.

Protocols and materials databases

DNASUi441425.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000611388; ENSP00000482325; ENSG00000276203.
GeneIDi441425.
KEGGihsa:441425.
UCSCiuc004acd.3. human.

Organism-specific databases

CTDi441425.
GeneCardsiGC09M043085.
HGNCiHGNC:31981. ANKRD20A3.
neXtProtiNX_Q5VUR7.
PharmGKBiPA143485301.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiCOG0666.
GeneTreeiENSGT00560000076605.
HOGENOMiHOG000230851.
HOVERGENiHBG079958.
InParanoidiQ5VUR7.
OMAiCNCVEER.
OrthoDBiEOG7N63KX.
PhylomeDBiQ5VUR7.
TreeFamiTF333496.

Miscellaneous databases

GenomeRNAii441425.
NextBioi110155.

Gene expression databases

BgeeiQ5VUR7.
GenevestigatoriQ5VUR7.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiA20A3_HUMAN
AccessioniPrimary (citable) accession number: Q5VUR7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 7, 2004
Last modified: February 4, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.