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Protein

Uncharacterized protein C1orf53

Gene

C1orf53

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C1orf53
Gene namesi
Name:C1orf53
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:30003. C1orf53.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672504.

Polymorphism and mutation databases

BioMutaiC1orf53.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Uncharacterized protein C1orf53PRO_0000271012Add
BLAST

Proteomic databases

MaxQBiQ5VUE5.
PaxDbiQ5VUE5.
PRIDEiQ5VUE5.

Expressioni

Tissue specificityi

Expressed in retina and retinoblastoma.1 Publication

Gene expression databases

BgeeiQ5VUE5.
CleanExiHS_C1orf53.
ExpressionAtlasiQ5VUE5. baseline and differential.
GenevisibleiQ5VUE5. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000356363.

Structurei

3D structure databases

ProteinModelPortaliQ5VUE5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG73756.
GeneTreeiENSGT00390000016548.
HOGENOMiHOG000010300.
HOVERGENiHBG079906.
InParanoidiQ5VUE5.
OMAiARQIWAL.
OrthoDBiEOG7TJ3KD.
PhylomeDBiQ5VUE5.
TreeFamiTF313973.

Sequencei

Sequence statusi: Complete.

Q5VUE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARQIWART GAALCRQPSA APPPAPLWVR AGFRQQLSLT LCPANEGNCG
60 70 80 90 100
GSAPSTPGRP ERAARPSVSE ELTAAERQIA ELHAAACAAG QLNYVDPATG
110 120 130 140
YVVLTQIAHL QRGECCGSAC RHCPYGQVNV KDPSKKKQFN SYFYV
Length:145
Mass (Da):15,483
Last modified:December 7, 2004 - v1
Checksum:iC5475E4B4073223A
GO

Sequence cautioni

The sequence CAH71759.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590115 Genomic DNA. Translation: CAH71758.1.
AL590115 Genomic DNA. Translation: CAH71759.1. Sequence problems.
BC038214 mRNA. No translation available.
BC130608 mRNA. Translation: AAI30609.1.
BC130634 mRNA. Translation: AAI30635.1.
CCDSiCCDS44290.1.
RefSeqiNP_001019765.1. NM_001024594.2.
UniGeneiHs.61329.

Genome annotation databases

EnsembliENST00000367393; ENSP00000356363; ENSG00000203724.
GeneIDi388722.
KEGGihsa:388722.
UCSCiuc001guh.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590115 Genomic DNA. Translation: CAH71758.1.
AL590115 Genomic DNA. Translation: CAH71759.1. Sequence problems.
BC038214 mRNA. No translation available.
BC130608 mRNA. Translation: AAI30609.1.
BC130634 mRNA. Translation: AAI30635.1.
CCDSiCCDS44290.1.
RefSeqiNP_001019765.1. NM_001024594.2.
UniGeneiHs.61329.

3D structure databases

ProteinModelPortaliQ5VUE5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000356363.

Polymorphism and mutation databases

BioMutaiC1orf53.

Proteomic databases

MaxQBiQ5VUE5.
PaxDbiQ5VUE5.
PRIDEiQ5VUE5.

Protocols and materials databases

DNASUi388722.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367393; ENSP00000356363; ENSG00000203724.
GeneIDi388722.
KEGGihsa:388722.
UCSCiuc001guh.3. human.

Organism-specific databases

CTDi388722.
GeneCardsiGC01P197871.
H-InvDBHIX0029272.
HGNCiHGNC:30003. C1orf53.
neXtProtiNX_Q5VUE5.
PharmGKBiPA142672504.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG73756.
GeneTreeiENSGT00390000016548.
HOGENOMiHOG000010300.
HOVERGENiHBG079906.
InParanoidiQ5VUE5.
OMAiARQIWAL.
OrthoDBiEOG7TJ3KD.
PhylomeDBiQ5VUE5.
TreeFamiTF313973.

Miscellaneous databases

GenomeRNAii388722.
NextBioi102320.
PROiQ5VUE5.

Gene expression databases

BgeeiQ5VUE5.
CleanExiHS_C1orf53.
ExpressionAtlasiQ5VUE5. baseline and differential.
GenevisibleiQ5VUE5. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  3. "KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers."
    Corson T.W., Huang A., Tsao M.-S., Gallie B.L.
    Oncogene 24:4741-4753(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.

Entry informationi

Entry nameiCA053_HUMAN
AccessioniPrimary (citable) accession number: Q5VUE5
Secondary accession number(s): A1L4N2, Q5VUE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 7, 2004
Last modified: July 22, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.