Q5VUE5 (CA053_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C1orf53

Gene names

Name:

C1orf53

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Tissue specificity	Expressed in retina and retinoblastoma. Ref.3
Sequence caution	The sequence CAH71759.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 145	145	Uncharacterized protein C1orf53		PRO_0000271012

Sequences

	Sequence		Length	Mass (Da)
	Q5VUE5 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: C5475E4B4073223A	FASTA	145	15,483
	10 20 30 40 50 60 MAARQIWART GAALCRQPSA APPPAPLWVR AGFRQQLSLT LCPANEGNCG GSAPSTPGRP 70 80 90 100 110 120 ERAARPSVSE ELTAAERQIA ELHAAACAAG QLNYVDPATG YVVLTQIAHL QRGECCGSAC 130 140 RHCPYGQVNV KDPSKKKQFN SYFYV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
[3]	"KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers." Corson T.W., Huang A., Tsao M.-S., Gallie B.L. Oncogene 24:4741-4753(2005) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL590115 Genomic DNA. Translation: CAH71758.1. AL590115 Genomic DNA. Translation: CAH71759.1. Sequence problems. BC038214 mRNA. No translation available. BC130608 mRNA. Translation: AAI30609.1. BC130634 mRNA. Translation: AAI30635.1.
IPI	IPI00374044.
RefSeq	NP_001019765.1. NM_001024594.2.
UniGene	Hs.61329.
3D structure databases
ProteinModelPortal	Q5VUE5.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000356363.
Proteomic databases
PaxDb	Q5VUE5.
PRIDE	Q5VUE5.
Protocols and materials databases
DNASU	388722.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000367393; ENSP00000356363; ENSG00000203724.
GeneID	388722.
KEGG	hsa:388722.
UCSC	uc001guh.3. human.
Organism-specific databases
CTD	388722.
GeneCards	GC01P197871.
H-InvDB	HIX0029272.
HGNC	HGNC:30003. C1orf53.
neXtProt	NX_Q5VUE5.
PharmGKB	PA142672504.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG73756.
HOGENOM	HOG000010300.
HOVERGEN	HBG079906.
InParanoid	Q5VUE5.
OMA	GPALWRQ.
OrthoDB	EOG4X3H2M.
Gene expression databases
Bgee	Q5VUE5.
CleanEx	HS_C1orf53.
Genevestigator	Q5VUE5.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	388722.
NextBio	102320.

Entry information

Entry name

CA053_HUMAN

Accession

Primary (citable) accession number: Q5VUE5
Secondary accession number(s): A1L4N2, Q5VUE4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	December 7, 2004
Last modified:	April 3, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.