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Q5VUE5 (CA053_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C1orf53
Gene names
Name:C1orf53
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Tissue specificity

Expressed in retina and retinoblastoma. Ref.3

Sequence caution

The sequence CAH71759.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 145145Uncharacterized protein C1orf53
PRO_0000271012

Sequences

Sequence LengthMass (Da)Tools
Q5VUE5 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: C5475E4B4073223A

FASTA14515,483
        10         20         30         40         50         60 
MAARQIWART GAALCRQPSA APPPAPLWVR AGFRQQLSLT LCPANEGNCG GSAPSTPGRP 

        70         80         90        100        110        120 
ERAARPSVSE ELTAAERQIA ELHAAACAAG QLNYVDPATG YVVLTQIAHL QRGECCGSAC 

       130        140 
RHCPYGQVNV KDPSKKKQFN SYFYV 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
[3]"KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers."
Corson T.W., Huang A., Tsao M.-S., Gallie B.L.
Oncogene 24:4741-4753(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL590115 Genomic DNA. Translation: CAH71758.1.
AL590115 Genomic DNA. Translation: CAH71759.1. Sequence problems.
BC038214 mRNA. No translation available.
BC130608 mRNA. Translation: AAI30609.1.
BC130634 mRNA. Translation: AAI30635.1.
RefSeqNP_001019765.1. NM_001024594.2.
UniGeneHs.61329.

3D structure databases

ProteinModelPortalQ5VUE5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid132826. 1 interaction.
STRING9606.ENSP00000356363.

Proteomic databases

PaxDbQ5VUE5.
PRIDEQ5VUE5.

Protocols and materials databases

DNASU388722.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000367393; ENSP00000356363; ENSG00000203724.
GeneID388722.
KEGGhsa:388722.
UCSCuc001guh.3. human.

Organism-specific databases

CTD388722.
GeneCardsGC01P197871.
H-InvDBHIX0029272.
HGNCHGNC:30003. C1orf53.
neXtProtNX_Q5VUE5.
PharmGKBPA142672504.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG73756.
HOGENOMHOG000010300.
HOVERGENHBG079906.
InParanoidQ5VUE5.
OMARFNSYFY.
OrthoDBEOG7TJ3KD.
PhylomeDBQ5VUE5.
TreeFamTF313973.

Gene expression databases

BgeeQ5VUE5.
CleanExHS_C1orf53.
GenevestigatorQ5VUE5.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi388722.
NextBio102320.

Entry information

Entry nameCA053_HUMAN
AccessionPrimary (citable) accession number: Q5VUE5
Secondary accession number(s): A1L4N2, Q5VUE4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 7, 2004
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM