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Q5VUA4 (ZN318_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger protein 318
Alternative name(s):
Endocrine regulatory protein
Gene names
Name:ZNF318
ORF Names:HRIHFB2436
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length2279 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Repressed AR-mediated transcriptional activation. May act as a transcriptional regulator during spermatogenesis and, in particular, during meiotic division By similarity.

Subunit structure

Interacts with the N-terminal domain of AR By similarity.

Subcellular location

Nucleus Ref.4.

Tissue specificity

Expressed in endocrine tissue. Ref.1

Sequence similarities

Contains 2 matrin-type zinc fingers.

Sequence caution

The sequence AAD17298.1 differs from that shown. Reason: Erroneous initiation.

The sequence AAD47387.1 differs from that shown. Reason: Frameshift at positions 4 and 44.

The sequence AAH98434.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

The sequence AAH98434.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence starting in position 1214.

Ontologies

Keywords
   Biological processMeiosis
Transcription
Transcription regulation
   Cellular componentNucleus
   Coding sequence diversityAlternative splicing
Polymorphism
   DomainCoiled coil
Repeat
Zinc-finger
   LigandMetal-binding
Zinc
   Molecular functionRepressor
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmeiotic nuclear division

Inferred from electronic annotation. Source: UniProtKB-KW

regulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionnucleic acid binding

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q5VUA4-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q5VUA4-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1093-1117: TLDPYNRPWASKTQSEAKQDAIKRT → GQFQKSSDFQKEGLQQTFLPPERQG
     1118-2279: Missing.
Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 22792279Zinc finger protein 318
PRO_0000191807

Regions

Zinc finger1063 – 109735Matrin-type 1
Zinc finger1136 – 116631Matrin-type 2
Coiled coil315 – 34329 Potential
Coiled coil876 – 980105 Potential
Coiled coil1768 – 179225 Potential
Compositional bias41 – 10363Pro-rich
Compositional bias1201 – 1327127Lys-rich
Compositional bias1433 – 1541109Pro-rich

Amino acid modifications

Modified residue791Phosphoserine Ref.12
Modified residue811Phosphoserine Ref.12
Modified residue1361Phosphoserine Ref.7 Ref.12
Modified residue1731Phosphoserine Ref.7 Ref.9
Modified residue2141Phosphoserine Ref.7 Ref.9
Modified residue4641Phosphoserine Ref.10
Modified residue5271Phosphoserine Ref.10 Ref.12
Modified residue10371Phosphoserine Ref.12
Modified residue12431Phosphoserine Ref.5 Ref.10 Ref.12
Modified residue14201Phosphoserine Ref.10
Modified residue17131Phosphoserine Ref.9
Modified residue18961Phosphoserine Ref.7 Ref.10
Modified residue21011Phosphoserine Ref.10 Ref.12
Modified residue21891Phosphoserine Ref.7
Modified residue21921Phosphoserine Ref.7
Modified residue22431Phosphoserine Ref.7 Ref.10

Natural variations

Alternative sequence1093 – 111725TLDPY…AIKRT → GQFQKSSDFQKEGLQQTFLP PERQG in isoform 2.
VSP_016592
Alternative sequence1118 – 22791162Missing in isoform 2.
VSP_016593
Natural variant4071S → I.
Corresponds to variant rs34541323 [ dbSNP | Ensembl ].
VAR_053759
Natural variant8121N → S in a breast cancer sample; somatic mutation. Ref.13
VAR_036056
Natural variant8701L → V.
Corresponds to variant rs9357410 [ dbSNP | Ensembl ].
VAR_053760
Natural variant12741G → R in a breast cancer sample; somatic mutation. Ref.13
VAR_036057
Natural variant12921T → I.
Corresponds to variant rs10948072 [ dbSNP | Ensembl ].
VAR_053761
Natural variant15801A → T.
Corresponds to variant rs3734684 [ dbSNP | Ensembl ].
VAR_053762
Natural variant15831T → I.
Corresponds to variant rs36107018 [ dbSNP | Ensembl ].
VAR_053763
Natural variant17971V → A. Ref.1
Corresponds to variant rs1459675 [ dbSNP | Ensembl ].
VAR_053764

Experimental info

Sequence conflict621G → R in AAD47387. Ref.1
Sequence conflict751G → V in AAD47387. Ref.1
Sequence conflict751G → V in AAD17298. Ref.1
Sequence conflict1034 – 10352RT → CI in AAD47387. Ref.1
Sequence conflict1034 – 10352RT → CI in AAD17298. Ref.1
Sequence conflict12591L → F in AAD47387. Ref.1
Sequence conflict12591L → F in AAD17298. Ref.1
Sequence conflict13491R → G in AAD47387. Ref.1
Sequence conflict13491R → G in AAD17298. Ref.1
Sequence conflict21601S → F in AAD47387. Ref.1
Sequence conflict21601S → F in AAD17298. Ref.1
Sequence conflict21731V → D in BAA34799. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: CC8F7D54710E2450

FASTA2,279251,112
        10         20         30         40         50         60 
MYRSSARSSV SSHRPKDDGG GGPRSGRSSG SSSGPARRSS PPPPPSGSSS RTPARRPRSP 

        70         80         90        100        110        120 
SGHRGRRASP SPPRGRRVSP SPPRARRGSP SPPRGRRLFP PGPAGFRGSS RGESRADYAR 

       130        140        150        160        170        180 
DGRGDHPGDS GSRRRSPGLC SDSLEKSLRI TVGNDHFCVS TPERRRLSDR LGSPVDNLED 

       190        200        210        220        230        240 
MDRDDLTDDS VFTRSSQCSR GLERYISQEE GPLSPFLGQL DEDYRTKETF LHRSDYSPHI 

       250        260        270        280        290        300 
SCHDELLRGT ERNREKLKGY SIRSEERSRE AKRPRYDDTV KINSMGGDHP SFTSGTRNYR 

       310        320        330        340        350        360 
QRRRSPSPRF LDPEFRELDL ARRKREEEEE RSRSLSQELV GVDGGGTGCS IPGLSGVLTA 

       370        380        390        400        410        420 
SEPGYSLHRP EEVSVMPKKS ILKKRIEVDI MEPSMQLESF SSSTSSSQDH PLYSGHPSLP 

       430        440        450        460        470        480 
LSGAIAAFAS EIENKGTMVE TALKEPQGNL YQWGPLPGIP KDNSPLREKF GSFLCHKDNL 

       490        500        510        520        530        540 
DLKAEGPERH TDFLLPHERA SQDGSGFSRI LSMLADSTST QEKRRRSFPD IEDEEKFLYG 

       550        560        570        580        590        600 
DEEEDLKAES VPKPLGSSES EVMRQKASSL PSSAPAVKLE SLEETNPEYA KIHDLLKTIG 

       610        620        630        640        650        660 
LDIGVAEISQ LAARTQERLH GKKPSLRSSA DRRSSVDRYF SADHCSSVDH RFSADRCSSV 

       670        680        690        700        710        720 
DHCFSADRRS SDPHRLESRE AHHSNTHSPE VSHPHPPSPV DPYLLTKNSP PFLKSDHPVG 

       730        740        750        760        770        780 
HISGPEVVGS GFQSSVAVRC MLPSAPSAPI RLPHTAALSQ FHMPRASQFA AARIPPNYQG 

       790        800        810        820        830        840 
PAIPPASFDA YRHYMAYAAS RWPMYPTSQP SNHPVPEPHR IMPITKQATR SRPNLRVIPT 

       850        860        870        880        890        900 
VTPDKPKQKE SLRGSIPAAQ VPVQVSIPSL IRYNPEKISD EKNRASQKQK VIEEREKLKN 

       910        920        930        940        950        960 
DREARQKKMY YLRTELERLH KQQGEMLRKK RREKDGHKDP LLVEVSRLQD NIMKDIAELR 

       970        980        990       1000       1010       1020 
QEAEEAEKKQ SELDKVAQIL GINIFDKSQK SLSDSREPTE KPGKAEKSKS PEKVSSFSNS 

      1030       1040       1050       1060       1070       1080 
SSNKESKVNN EKFRTKSPKP AESPQSATKQ LDQPTAAYEY YDAGNHWCKD CNTICGTMFD 

      1090       1100       1110       1120       1130       1140 
FFTHMHNKKH TQTLDPYNRP WASKTQSEAK QDAIKRTDKI TVPAKGSEFL VPISGFYCQL 

      1150       1160       1170       1180       1190       1200 
CEEFLGDPIS GEQHVKGHQH NEKYKKYVDE NPLYEERRNL DRQAGLAVVL ETERRRQSEL 

      1210       1220       1230       1240       1250       1260 
KRKLSEKPKE EKKEKKAKAV KEVKEDDKVS EKLEDQLSEG RNSPEKAENK RNTGIKLQLK 

      1270       1280       1290       1300       1310       1320 
EEVKKESPTS SSFGKFSWKK PEKEEEKSSL VTPSISKEEI LESSKDKEDG KTEAGKAKPI 

      1330       1340       1350       1360       1370       1380 
KIKLSGKTVV AHTSPWMPVV TTSTQTKIRP NLPIPSTVLR KSCSATMSKP APLNTFLSIK 

      1390       1400       1410       1420       1430       1440 
SSGTTAKPLP VVKESSADLL LPPDIISKAF GGEEVILKGS PEEKVVLAEK SEPSHLPEQI 

      1450       1460       1470       1480       1490       1500 
LPPPPPPPPP PPPPPPVIPH PAAPSAAQAN AILAPVKSNP VVSQTLSPGF VGPNILNPVL 

      1510       1520       1530       1540       1550       1560 
PVAIMASAQP AAIPSDETAP GVSESDRDQT LFSVLVRPPP PLSSVFSEQA KKLEKRNSCL 

      1570       1580       1590       1600       1610       1620 
ATANAKDLYD IFYSSGGKGA PETKGAPETK LSGGPLANGE NSNLSRTKSS DTSSTSPLNS 

      1630       1640       1650       1660       1670       1680 
SASQEELHQD EGLVAAPIVS NSEKPIAKTL VALGKWSVVE HVGPKSTGST YGFLQPLTRL 

      1690       1700       1710       1720       1730       1740 
CQSRPYETIT PKTDTLAIWT SSSFQSDTSR DISPEKSELD LGEPGPPGVE PPPQLLDIQC 

      1750       1760       1770       1780       1790       1800 
KESQKLVEIH LRESVNQDKE SQELRKSEDC RESEIETNTE LKERVKELSE GIVDEGVSTS 

      1810       1820       1830       1840       1850       1860 
IGPHSIDDSN LNHGNRYMWE GEVKQPNLLM IDKEAEQSNK LMTGSETPSK VVIKLSPQAC 

      1870       1880       1890       1900       1910       1920 
SFTKAKLDSF LSEARSLLNP QDTPVKISAP ELLLHSPARS AMCLTGSPQE QGVSVVSEEG 

      1930       1940       1950       1960       1970       1980 
LENSAPESAS RTSRYRSLKL KRERSKDFQV KKIYELAVWD ENKKRPETWE SPEKPKTEAL 

      1990       2000       2010       2020       2030       2040 
ELQDVHPELT VTIESKALED FEATDLKVEE LTALGNLGDM PVDFCTTRVS PAHRSPTVLC 

      2050       2060       2070       2080       2090       2100 
QKVCEENSVS PIGCNSSDPA DFEPIPSFSG FPLDSPKTLV LDFETEGERN SPNPRSVRIP 

      2110       2120       2130       2140       2150       2160 
SPNILKTGLT ENVDRGLGGL EGTHQALDLL AGGMMPEEVK ESSQLDKQES LGLELKTINS 

      2170       2180       2190       2200       2210       2220 
AGLGPSPCLP DLVDFVTRTS GVQKDKLCSP LSEPGDPSKC SSLELGPLQL EISNASTTEV 

      2230       2240       2250       2260       2270 
AILQVDDDSG DPLNLVKAPV SRSPPREQVI EDNMVPQGMP EQETTVGAIQ DHTESSVHN 

« Hide

Isoform 2 [UniParc].

Checksum: 65866465A953CF07
Show »

FASTA1,117124,880

References

« Hide 'large scale' references
[1]"A novel cDNA expressed in endocrine tissue."
Lopez-Egido J.R., Oberg K., Gobl A.E.
Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, VARIANT ALA-1797.
[2]"The DNA sequence and analysis of human chromosome 6."
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1213 (ISOFORM 1).
Tissue: Lymph and Testis.
[4]"Selection system for genes encoding nuclear-targeted proteins."
Ueki N., Oda T., Kondo M., Yano K., Noguchi T., Muramatsu M.-A.
Nat. Biotechnol. 16:1338-1342(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2056-2279 (ISOFORM 1), SUBCELLULAR LOCATION.
Tissue: Fetal brain.
[5]"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1243, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[6]"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.
Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic kidney.
[7]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-136; SER-173; SER-214; SER-1896; SER-2189; SER-2192 AND SER-2243, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[8]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-173; SER-214 AND SER-1713, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Leukemic T-cell.
[10]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-464; SER-527; SER-1243; SER-1420; SER-1896; SER-2101 AND SER-2243, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[11]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[12]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-79; SER-81; SER-136; SER-527; SER-1037; SER-1243 AND SER-2101, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[13]"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E.
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANTS [LARGE SCALE ANALYSIS] SER-812 AND ARG-1274.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF090114 mRNA. Translation: AAD47387.1. Frameshift.
AF121141 mRNA. Translation: AAD17298.1. Different initiation.
AL590383, AL583834 Genomic DNA. Translation: CAH71374.2.
AL583834, AL590383 Genomic DNA. Translation: CAI14459.2.
BC030687 mRNA. No translation available.
BC098434 mRNA. Translation: AAH98434.1. Sequence problems.
AB015342 mRNA. Translation: BAA34799.1.
CCDSCCDS4895.2. [Q5VUA4-1]
RefSeqNP_055160.2. NM_014345.2. [Q5VUA4-1]
UniGeneHs.509718.

3D structure databases

ProteinModelPortalQ5VUA4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid117299. 9 interactions.
IntActQ5VUA4. 2 interactions.
STRING9606.ENSP00000354964.

PTM databases

PhosphoSiteQ5VUA4.

Polymorphism databases

DMDM166215018.

Proteomic databases

MaxQBQ5VUA4.
PaxDbQ5VUA4.
PRIDEQ5VUA4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000318149; ENSP00000323032; ENSG00000171467. [Q5VUA4-2]
ENST00000361428; ENSP00000354964; ENSG00000171467. [Q5VUA4-1]
ENST00000605935; ENSP00000475748; ENSG00000171467. [Q5VUA4-2]
GeneID24149.
KEGGhsa:24149.
UCSCuc003oux.3. human. [Q5VUA4-1]

Organism-specific databases

CTD24149.
GeneCardsGC06M043346.
HGNCHGNC:13578. ZNF318.
HPAHPA027022.
HPA027031.
neXtProtNX_Q5VUA4.
PharmGKBPA134923137.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG87509.
HOGENOMHOG000043103.
HOVERGENHBG107139.
InParanoidQ5VUA4.
OMAQTKIRPN.
OrthoDBEOG71P298.
PhylomeDBQ5VUA4.
TreeFamTF350583.

Gene expression databases

BgeeQ5VUA4.
CleanExHS_ZNF318.
GenevestigatorQ5VUA4.

Family and domain databases

InterProIPR015880. Znf_C2H2-like.
IPR003604. Znf_U1.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 2 hits.
SM00451. ZnF_U1. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSZNF318. human.
GeneWikiZNF318.
GenomeRNAi24149.
NextBio46851.
PROQ5VUA4.

Entry information

Entry nameZN318_HUMAN
AccessionPrimary (citable) accession number: Q5VUA4
Secondary accession number(s): O94796 expand/collapse secondary AC list , Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: January 15, 2008
Last modified: July 9, 2014
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 6

Human chromosome 6: entries, gene names and cross-references to MIM