Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nuclear pore membrane glycoprotein 210-like

Gene

NUP210L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. Sertoli cell development Source: Ensembl
  2. spermatid development Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear pore membrane glycoprotein 210-like
Alternative name(s):
Nucleoporin 210 kDa-like
Nucleoporin Nup210-like
Gene namesi
Name:NUP210L
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:29915. NUP210L.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1813 – 183321HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134984604.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3535Sequence AnalysisAdd
BLAST
Chaini36 – 18881853Nuclear pore membrane glycoprotein 210-likePRO_0000236048Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi84 – 841N-linked (GlcNAc...)Sequence Analysis
Glycosylationi304 – 3041N-linked (GlcNAc...)Sequence Analysis
Glycosylationi348 – 3481N-linked (GlcNAc...)Sequence Analysis
Glycosylationi495 – 4951N-linked (GlcNAc...)Sequence Analysis
Glycosylationi522 – 5221N-linked (GlcNAc...)Sequence Analysis
Glycosylationi812 – 8121N-linked (GlcNAc...)Sequence Analysis
Glycosylationi931 – 9311N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1445 – 14451N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1859 – 18591N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ5VU65.
PaxDbiQ5VU65.
PRIDEiQ5VU65.

PTM databases

PhosphoSiteiQ5VU65.

Expressioni

Gene expression databases

BgeeiQ5VU65.
CleanExiHS_NUP210L.
ExpressionAtlasiQ5VU65. baseline and differential.
GenevestigatoriQ5VU65.

Interactioni

Protein-protein interaction databases

BioGridi124804. 1 interaction.
STRINGi9606.ENSP00000357547.

Structurei

3D structure databases

ProteinModelPortaliQ5VU65.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NUP210 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG315446.
GeneTreeiENSGT00390000009491.
HOGENOMiHOG000115312.
HOVERGENiHBG082098.
InParanoidiQ5VU65.
KOiK14314.
OMAiEIVTDHE.
OrthoDBiEOG7PS1DJ.
PhylomeDBiQ5VU65.
TreeFamiTF313331.

Family and domain databases

InterProiIPR003343. Big_2.
IPR008964. Invasin/intimin_cell_adhesion.
[Graphical view]
PfamiPF02368. Big_2. 1 hit.
[Graphical view]
SMARTiSM00635. BID_2. 1 hit.
[Graphical view]
SUPFAMiSSF49373. SSF49373. 2 hits.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q5VU65-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTGCPASSRR RGFGLFFFLR LHRLLLLFLV LRGTLANKLN VPQVLLPFGR
60 70 80 90 100
EPGRVPFLLE AQRGCYTWHS THHDAVTVEP LYENGTLCSQ KAVLIAESTQ
110 120 130 140 150
PIRLSSIILA REIVTDHELR CDVKVDVINS IEIVSRAREL YVDDSPLELM
160 170 180 190 200
VRALDAEGNT FSSLAGMMFE WSIAQDNESA REELSSKIRI LKYSEAEYAP
210 220 230 240 250
PIYIAEMEKE EKQGDVILVS GIRTGAAVVK VRIHEPFYKK VAAALIRLLV
260 270 280 290 300
LENIFLIPSH DIYLLVGTYI KYQVAKMVQG RVTEVKFPLE HYILELQDHR
310 320 330 340 350
VALNGSHSEK VAILDDKTAM VTASQLGQTN LVFVHKNVHM RSVSGLPNCT
360 370 380 390 400
IYVVEPGFLG FTVQPGNRWS LEVGQVYVIT VDVFDKSSTK VYISDNLRIT
410 420 430 440 450
YDFPKEYFEE QLTTVNGSYH IVKALKDGVV VINASLTSII YQNKDIQPIK
460 470 480 490 500
FLIKHQQEVK IYFPIMLTPK FLAFPHHPMG MLYRYKVQVE GGSGNFTWTS
510 520 530 540 550
SNETVVIVTT KGVVTAGQVR GNSTVLARDV QNPFRYGEIK IHVLKLNKME
560 570 580 590 600
LLPFHADVEI GQIIEIPIAM YHINKETKEA MAFTDCSHLS LDLNMDKQGV
610 620 630 640 650
FTLLKEGIQR PGPMHCSSTH IAAKSLGHTL VTVSVNECDK YLESSATFAA
660 670 680 690 700
YEPLKALNPV EVALVTWQSV KEMVFEGGPR PWILEPSRFF LELNAEKTEK
710 720 730 740 750
IGIAQVWLPS KRKQNQYIYR IQCLDLGEQV LTFRIGNHPG VLNPSPAVEV
760 770 780 790 800
LQVRFICAHP ASMSVTPVYK VPAGAQPCPL PQHNKWLIPV SRLRDTVLEL
810 820 830 840 850
AVFDQHRRKF DNFSSLMLEW KSSNETLAHF EDYKSVEMVA KDDGSGQTRL
860 870 880 890 900
HGHQILKVHQ IKGTVLIGVN FVGYSEKKSP KEISNLPRSV DVELLLVDDV
910 920 930 940 950
TVVPENATIY NHPDVKETFS LVEGSGYFLV NSSEQGVVTI TYMEAESSVE
960 970 980 990 1000
LVPLHPGFFT LEVYDLCLAF LGPATAHLRV SDIQELELDL IDKVEIDKTV
1010 1020 1030 1040 1050
LVTVRVLGSS KRPFQNKYFR NMELKLQLAS AIVTLTPMEQ QDEYSENYIL
1060 1070 1080 1090 1100
RATTIGQTTL VAIAKDKMGR KYTSTPRHIE VFPPFRLLPE KMTLIPMNMM
1110 1120 1130 1140 1150
QVMSEGGPQP QSIVHFSISN QTVAVVNRRG QVTGKIVGTA VVHGTIQTVN
1160 1170 1180 1190 1200
EDTGKVIVFS QDEVQIEVVQ LRAVRILAAA TRLITATKMP VYVMGVTSTQ
1210 1220 1230 1240 1250
TPFSFSNANP GLTFHWSMSK RDVLDLVPRH SEVFLQLPVE HNFAMVVHTK
1260 1270 1280 1290 1300
AAGRTSIKVT VHCMNSSSGQ FEGNLLELSD EVQILVFEKL QLFYPECQPE
1310 1320 1330 1340 1350
QILMPINSQL KLHTNREGAA FVSSRVLKCF PNSSVIEEDG EGLLKAGSIA
1360 1370 1380 1390 1400
GTAVLEVTSI EPFGVNQTTI TGVQVAPVTY LRVSSQPKLY TAQGRTLSAF
1410 1420 1430 1440 1450
PLGMSLTFTV QFYNSIGEKF HTHNTQLYLA LNRDDLLHIG PGNKNYTYMA
1460 1470 1480 1490 1500
QAVNRGLTLV GLWDRRHPGM ADYIPVAVEH AIEPDTKLTF VGDIICFSTH
1510 1520 1530 1540 1550
LVSQHGEPGI WMISANNILQ TDIVTGVGVA RSPGTAMIFH DIPGVVKTYR
1560 1570 1580 1590 1600
EVVVNASSRL MLSYDLKTYL TNTLNSTVFK LFITTGRNGV NLKGFCTPNQ
1610 1620 1630 1640 1650
ALAITKVLLP ATLMLCHVQF SNTLLDIPAS KVFQVHSDFS MEKGVYVCII
1660 1670 1680 1690 1700
KVRPQSEELL QALSVADTSV YGWATLVSER SKNGMQRILI PFIPAFYINQ
1710 1720 1730 1740 1750
SELVLSHKQD IGEIRVLGVD RVLRKLEVIS SSPVLVVAGH SHSPLTPGLA
1760 1770 1780 1790 1800
IYSVRVVNFT SFQQMASPVF INISCVLTSQ SEAVVVRAMK DKLGADHCED
1810 1820 1830 1840 1850
SAILKRFTGS YQILLLTLFA VLASTASIFL AYNAFLNKIQ TVPVVYVPTL
1860 1870 1880
GTPQPGFFNS TSSPPHFMSL QPPLAQSRLQ HWLWSIRH
Length:1,888
Mass (Da):210,605
Last modified:December 7, 2004 - v1
Checksum:iF8B1194A9BB5D986
GO
Isoform 2 (identifier: Q5VU65-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1644-1795: Missing.

Show »
Length:1,736
Mass (Da):193,998
Checksum:i5815738498B3D6DD
GO

Sequence cautioni

The sequence BAC86345.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC87279.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAB63757.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti318 – 3181T → A in BAC87225. (PubMed:14702039)Curated
Sequence conflicti506 – 5061V → I in BAC87225. (PubMed:14702039)Curated
Sequence conflicti843 – 8431D → G in BAC86345. (PubMed:14702039)Curated
Sequence conflicti898 – 8981D → G in BAC87279. (PubMed:14702039)Curated
Sequence conflicti1005 – 10051R → K in BAC87279. (PubMed:14702039)Curated
Sequence conflicti1686 – 16861Q → R in BAC87279. (PubMed:14702039)Curated
Sequence conflicti1833 – 18331N → S in BAC86345. (PubMed:14702039)Curated
Sequence conflicti1858 – 187215FNSTS…MSLQP → LTPQVLPLTS in BAC86345. (PubMed:14702039)CuratedAdd
BLAST

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti1491 – 14911V → I.
Corresponds to variant rs11264875 [ dbSNP | Ensembl ].
VAR_050574

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1644 – 1795152Missing in isoform 2. 1 PublicationVSP_053811Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125924 mRNA. Translation: BAC86345.1. Different initiation.
AK128000 mRNA. Translation: BAC87225.1.
AK128108 mRNA. Translation: BAC87279.1. Different initiation.
AL590431, AL358472, AL513546 Genomic DNA. Translation: CAH71259.1.
AL358472 Genomic DNA. Translation: CAI14034.1. Sequence problems.
AL513546, AL358472, AL590431 Genomic DNA. Translation: CAH70552.1.
AL358472, AL590431, AL513546 Genomic DNA. Translation: CAI14015.1.
AL833964 mRNA. Translation: CAD38812.1.
AL133633 mRNA. Translation: CAB63757.1. Different initiation.
CCDSiCCDS41399.1. [Q5VU65-1]
CCDS53370.1. [Q5VU65-2]
PIRiT43452.
RefSeqiNP_001152956.1. NM_001159484.1. [Q5VU65-2]
NP_997191.2. NM_207308.2. [Q5VU65-1]
UniGeneiHs.67639.

Genome annotation databases

EnsembliENST00000271854; ENSP00000271854; ENSG00000143552. [Q5VU65-2]
ENST00000368559; ENSP00000357547; ENSG00000143552. [Q5VU65-1]
GeneIDi91181.
KEGGihsa:91181.
UCSCiuc001fdw.3. human. [Q5VU65-1]

Polymorphism databases

DMDMi74747057.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125924 mRNA. Translation: BAC86345.1. Different initiation.
AK128000 mRNA. Translation: BAC87225.1.
AK128108 mRNA. Translation: BAC87279.1. Different initiation.
AL590431, AL358472, AL513546 Genomic DNA. Translation: CAH71259.1.
AL358472 Genomic DNA. Translation: CAI14034.1. Sequence problems.
AL513546, AL358472, AL590431 Genomic DNA. Translation: CAH70552.1.
AL358472, AL590431, AL513546 Genomic DNA. Translation: CAI14015.1.
AL833964 mRNA. Translation: CAD38812.1.
AL133633 mRNA. Translation: CAB63757.1. Different initiation.
CCDSiCCDS41399.1. [Q5VU65-1]
CCDS53370.1. [Q5VU65-2]
PIRiT43452.
RefSeqiNP_001152956.1. NM_001159484.1. [Q5VU65-2]
NP_997191.2. NM_207308.2. [Q5VU65-1]
UniGeneiHs.67639.

3D structure databases

ProteinModelPortaliQ5VU65.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124804. 1 interaction.
STRINGi9606.ENSP00000357547.

PTM databases

PhosphoSiteiQ5VU65.

Polymorphism databases

DMDMi74747057.

Proteomic databases

MaxQBiQ5VU65.
PaxDbiQ5VU65.
PRIDEiQ5VU65.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000271854; ENSP00000271854; ENSG00000143552. [Q5VU65-2]
ENST00000368559; ENSP00000357547; ENSG00000143552. [Q5VU65-1]
GeneIDi91181.
KEGGihsa:91181.
UCSCiuc001fdw.3. human. [Q5VU65-1]

Organism-specific databases

CTDi91181.
GeneCardsiGC01M153965.
H-InvDBHIX0001099.
HGNCiHGNC:29915. NUP210L.
neXtProtiNX_Q5VU65.
PharmGKBiPA134984604.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG315446.
GeneTreeiENSGT00390000009491.
HOGENOMiHOG000115312.
HOVERGENiHBG082098.
InParanoidiQ5VU65.
KOiK14314.
OMAiEIVTDHE.
OrthoDBiEOG7PS1DJ.
PhylomeDBiQ5VU65.
TreeFamiTF313331.

Miscellaneous databases

ChiTaRSiNUP210L. human.
GenomeRNAii91181.
NextBioi77138.
PROiQ5VU65.

Gene expression databases

BgeeiQ5VU65.
CleanExiHS_NUP210L.
ExpressionAtlasiQ5VU65. baseline and differential.
GenevestigatoriQ5VU65.

Family and domain databases

InterProiIPR003343. Big_2.
IPR008964. Invasin/intimin_cell_adhesion.
[Graphical view]
PfamiPF02368. Big_2. 1 hit.
[Graphical view]
SMARTiSM00635. BID_2. 1 hit.
[Graphical view]
SUPFAMiSSF49373. SSF49373. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Testis.
  2. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 723-1888 (ISOFORMS 1 AND 2).
    Tissue: Testis.

Entry informationi

Entry nameiP210L_HUMAN
AccessioniPrimary (citable) accession number: Q5VU65
Secondary accession number(s): E7EP56
, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6, Q9UF31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: December 7, 2004
Last modified: January 7, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.