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Protein
Submitted name:

Adducin 3 (Gamma), isoform CRA_a

Gene

ADD3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Adducin 3 (Gamma), isoform CRA_aImported
Submitted name:
cDNA FLJ77558, highly similar to Homo sapiens adducin 3 (gamma) (ADD3), transcript variant 1, mRNAImported
Gene namesi
Name:ADD3Imported
ORF Names:hCG_1789399Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24567.

Expressioni

Gene expression databases

BgeeiENSG00000148700.

Interactioni

Protein-protein interaction databases

MINTiMINT-5005052.
STRINGi9606.ENSP00000348381.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini139 – 321Aldolase_IIInterPro annotationAdd BLAST183

Phylogenomic databases

eggNOGiKOG3699. Eukaryota.
COG0235. LUCA.
HOVERGENiHBG004180.
KOiK18622.
OMAiKEQDHII.
OrthoDBiEOG091G0324.

Family and domain databases

Gene3Di3.40.225.10. 1 hit.
InterProiIPR027772. ADD3.
IPR001303. Aldolase_II/adducin_N.
[Graphical view]
PANTHERiPTHR10672:SF5. PTHR10672:SF5. 1 hit.
PfamiPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTiSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMiSSF53639. SSF53639. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5VU08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDASQGVI TTPPPPSMPH KERYFDRINE NDPEYIRERN MSPDLRQDFN
60 70 80 90 100
MMEQRKRVTQ ILQSPAFRED LECLIQEQMK KGHNPTGLLA LQQIADYIMA
110 120 130 140 150
NSFSGFSSPP LSLGMVTPIN DLPGADTSSY VKGEKLTRCK LASLYRLVDL
160 170 180 190 200
FGWAHLANTY ISVRISKEQD HIIIIPRGLS FSEATASNLV KVNIIGEVVD
210 220 230 240 250
QGSTNLKIDH TGFSPHAAIY STRPDVKCVI HIHTLATAAV SSMKCGILPI
260 270 280 290 300
SQESLLLGDV AYYDYQGSLE EQEERIQLQK VLGPSCKVLV LRNHGVVALG
310 320 330 340 350
ETLEEAFHYI FNVQLACEIQ VQALAGAGGV DNLHVLDFQK YKAFTYTVAA
360 370 380 390 400
SGGGGVNMGS HQKWKVGEIE FEGLMRTLDN LGYRTGYAYR HPLIREKPRH
410 420 430 440 450
KSDVEIPATV TAFSFEDDTV PLSPLKYMAQ RQQREKTRWL NSPNTYMKVN
460 470 480 490 500
VPEESRNGET SPRTKITWMK AEDSSKVSGG TPIKIEDPNQ FVPLNTNPNE
510 520 530 540 550
VLEKRNKIRE QNRYDLKTAG PQSQLLAGIV VDKPPSTMQF EDDDHGPPAP
560 570 580 590 600
PNPFSHLTEG ELEEYKRTIE RKQQGLEDAE QELLSDDASS VSQIQSQTQS
610 620 630 640 650
PQNVPEKLEE NHELFSKSFI SMEVPVMVVN GKDDMHDVED ELAKRVSRLS
660 670 680 690 700
TSTTIENIEI TIKSPEKIEE VLSPEGSPSK SPSKKKKKFR TPSFLKKNKK

KEKVEA
Length:706
Mass (Da):79,155
Last modified:May 10, 2005 - v1
Checksum:iEB8EAF602A4D7B41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291488 mRNA. Translation: BAF84177.1.
CH471066 Genomic DNA. Translation: EAW49571.1.
CH471066 Genomic DNA. Translation: EAW49572.1.
RefSeqiNP_001307520.1. NM_001320591.1.
NP_001307521.1. NM_001320592.1.
NP_001307522.1. NM_001320593.1.
NP_058432.1. NM_016824.4.
UniGeneiHs.501012.

Genome annotation databases

GeneIDi120.
KEGGihsa:120.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291488 mRNA. Translation: BAF84177.1.
CH471066 Genomic DNA. Translation: EAW49571.1.
CH471066 Genomic DNA. Translation: EAW49572.1.
RefSeqiNP_001307520.1. NM_001320591.1.
NP_001307521.1. NM_001320592.1.
NP_001307522.1. NM_001320593.1.
NP_058432.1. NM_016824.4.
UniGeneiHs.501012.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-5005052.
STRINGi9606.ENSP00000348381.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi120.
KEGGihsa:120.

Organism-specific databases

CTDi120.
PharmGKBiPA24567.

Phylogenomic databases

eggNOGiKOG3699. Eukaryota.
COG0235. LUCA.
HOVERGENiHBG004180.
KOiK18622.
OMAiKEQDHII.
OrthoDBiEOG091G0324.

Miscellaneous databases

ChiTaRSiADD3. human.
GenomeRNAii120.

Gene expression databases

BgeeiENSG00000148700.

Family and domain databases

Gene3Di3.40.225.10. 1 hit.
InterProiIPR027772. ADD3.
IPR001303. Aldolase_II/adducin_N.
[Graphical view]
PANTHERiPTHR10672:SF5. PTHR10672:SF5. 1 hit.
PfamiPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTiSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMiSSF53639. SSF53639. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5VU08_HUMAN
AccessioniPrimary (citable) accession number: Q5VU08
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 30, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.