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Protein
Submitted name:

Protocadherin-9

Gene

PCDH9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin-9Imported
Gene namesi
Name:PCDH9Imported
ORF Names:hCG_2026614Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000184226.14
HGNCiHGNC:8661 PCDH9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei812 – 836HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184226

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501458712124 – 1032Sequence analysisAdd BLAST1009

Expressioni

Gene expression databases

BgeeiENSG00000184226

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 140CAInterPro annotationAdd BLAST92
Domaini164 – 250CAInterPro annotationAdd BLAST87
Domaini274 – 356CAInterPro annotationAdd BLAST83
Domaini386 – 467CAInterPro annotationAdd BLAST82
Domaini491 – 570CAInterPro annotationAdd BLAST80
Domaini594 – 673CAInterPro annotationAdd BLAST80
Domaini700 – 782CAInterPro annotationAdd BLAST83

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00910000143986
HOVERGENiHBG053523

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
IPR013585 Protocadherin
PfamiView protein in Pfam
PF00028 Cadherin, 6 hits
PF08266 Cadherin_2, 1 hit
PF08374 Protocadherin, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 7 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 3 hits

Sequencei

Sequence statusi: Complete.

Q5VT82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLRDFYLLA ALIACLRLDS AIAQELIYTI REELPENVPI GNIPKDLNIS
60 70 80 90 100
HINAATGTSA SLVYRLVSKA GDAPLVKVSS STGEIFTTSN RIDREKLCAG
110 120 130 140 150
ASYAEENECF FELEVVILPN DFFRLIKIKI IVKDTNDNAP MFPSPVINIS
160 170 180 190 200
IPENTLINSR FPIPSATDPD TGFNGVQHYE LLNGQSVFGL DIVETPEGEK
210 220 230 240 250
WPQLIVQQNL DREQKDTYVM KIKVEDGGTP QKSSTAILQV TVSDVNDNRP
260 270 280 290 300
VFKEGQVEVH IPENAPVGTS VIQLHATDAD IGSNAEIRYI FGAQVAPATK
310 320 330 340 350
RLFALNNTTG LITVQRSLDR EETAIHKVTV LASDGSSTPA RATVTINVTD
360 370 380 390 400
VNDNPPNIDL RYIISPINGT VYLSEKDPVN TKIALITVSD KDTDVNGKVI
410 420 430 440 450
CFIEREVPFH LKAVYDNQYL LETSSLLDYE GTKEFSFKIV ASDSGKPSLN
460 470 480 490 500
QTALVRVKLE DENDNPPIFN QPVIELSVSE NNRRGLYLTT ISATDEDSGK
510 520 530 540 550
NADIVYQLGP NASFFDLDRK TGVLTASRVF DREEQERFIF TVTARDNGTP
560 570 580 590 600
PLQSQAAVIV TVLDENDNSP KFTHNHFQFF VSENLPKYST VGVITVTDAD
610 620 630 640 650
AGENKAVTLS ILNDNDNFVL DPYSGVIKSN VSFDREQQSS YTFDVKATDG
660 670 680 690 700
GQPPRSSTAK VTINVMDVND NSPVVISPPS NTSFKLVPLS AIPGSVVAEV
710 720 730 740 750
FAVDVDTGMN AELKYTIVSG NNKGLFRIDP VTGNITLEEK PAPTDVGLHR
760 770 780 790 800
LVVNISDLGY PKSLHTLVLV FLYVNDTAGN ASYIYDLIRR TMETPLDRNI
810 820 830 840 850
GDSSQPYQNE DYLTIMIAII AGAMVVIVVI FVTVLVRCRH ASRFKAAQRS
860 870 880 890 900
KQGAEWMSPN QENKQNKKKK RKKRKSPKSS LLNFVTIEES KPDDAVHEPI
910 920 930 940 950
NGTISLPAEL EEQSIGRFDW GPAPPTTFKP NSPDLAKHYK SASPQPAFHL
960 970 980 990 1000
KPDTPVSVKK HHVIQELPLD NTFVGGCDTL SKRSSTSSDH FSASECSSQG
1010 1020 1030
GFKTKGPLHT RQVNEHFYWS ISTAYKCPVN QY
Length:1,032
Mass (Da):113,711
Last modified:December 7, 2004 - v1
Checksum:i965E08EF7D3B9C79
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136999 Genomic DNA No translation available.
AL138682 Genomic DNA No translation available.
AL138814 Genomic DNA No translation available.
AL355173 Genomic DNA No translation available.
AL356305 Genomic DNA No translation available.
AL450107 Genomic DNA No translation available.
KF455795 Genomic DNA No translation available.
KF455796 Genomic DNA No translation available.
CH471093 Genomic DNA Translation: EAW80499.1
RefSeqiNP_001305303.1, NM_001318374.1
UniGeneiHs.654709
Hs.675386

Genome annotation databases

EnsembliENST00000377861; ENSP00000367092; ENSG00000184226
GeneIDi5101
UCSCiuc001vin.4 human

Similar proteinsi

Entry informationi

Entry nameiQ5VT82_HUMAN
AccessioniPrimary (citable) accession number: Q5VT82
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: May 23, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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