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Protein
Submitted name:

G protein-coupled receptor 34

Gene

GPR34

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor 34Imported
Submitted name:
G protein-coupled receptor 34, isoform CRA_aImported
Submitted name:
G-protein-coupled receptor 34Imported
Gene namesi
Name:GPR34Imported
ORF Names:hCG_1818087Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei61 – 80HelicalSequence analysisAdd BLAST20
Transmembranei92 – 113HelicalSequence analysisAdd BLAST22
Transmembranei133 – 150HelicalSequence analysisAdd BLAST18
Transmembranei171 – 192HelicalSequence analysisAdd BLAST22
Transmembranei217 – 241HelicalSequence analysisAdd BLAST25
Transmembranei269 – 291HelicalSequence analysisAdd BLAST23
Transmembranei311 – 330HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28878.

Expressioni

Gene expression databases

BgeeiENSG00000171659.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000367378.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 327G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST257

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IH53. Eukaryota.
ENOG410ZHRR. LUCA.
HOVERGENiHBG063715.
KOiK08383.
OMAiYHAFRFV.
OrthoDBiEOG091G0DKA.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VT14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSHTITMTT TSVSSWPYSS HRMRFITNHS DQPPQNFSAT PNVTTCPMDE
60 70 80 90 100
KLLSTVLTTS YSVIFIVGLV GNIIALYVFL GIHRKRNSIQ IYLLNVAIAD
110 120 130 140 150
LLLIFCLPFR IMYHINQNKW TLGVILCKVV GTLFYMNMYI SIILLGFISL
160 170 180 190 200
DRYIKINRSI QQRKAITTKQ SIYVCCIVWM LALGGFLTMI ILTLKKGGHN
210 220 230 240 250
STMCFHYRDK HNAKGEAIFN FILVVMFWLI FLLIILSYIK IGKNLLRISK
260 270 280 290 300
RRSKFPNSGK YATTARNSFI VLIIFTICFV PYHAFRFIYI SSQLNVSSCY
310 320 330 340 350
WKEIVHKTNE IMLVLSSFNS CLDPVMYFLM SSNIRKIMCQ LLFRRFQGEP
360 370 380
SRSESTSEFK PGYSLHDTSV AVKIQSSSKS T
Length:381
Mass (Da):43,860
Last modified:May 10, 2005 - v1
Checksum:i491FC016E5624379
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ106398 mRNA. Translation: AAZ99227.1.
DQ106401 mRNA. Translation: AAZ99230.1.
JF810887 Genomic DNA. Translation: AEP43754.1.
CH471141 Genomic DNA. Translation: EAW59396.1.
CH471141 Genomic DNA. Translation: EAW59397.1.
RefSeqiNP_001091048.1. NM_001097579.1.
NP_005291.1. NM_005300.3.
XP_005272654.1. XM_005272597.3.
UniGeneiHs.495989.

Genome annotation databases

GeneIDi2857.
KEGGihsa:2857.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ106398 mRNA. Translation: AAZ99227.1.
DQ106401 mRNA. Translation: AAZ99230.1.
JF810887 Genomic DNA. Translation: AEP43754.1.
CH471141 Genomic DNA. Translation: EAW59396.1.
CH471141 Genomic DNA. Translation: EAW59397.1.
RefSeqiNP_001091048.1. NM_001097579.1.
NP_005291.1. NM_005300.3.
XP_005272654.1. XM_005272597.3.
UniGeneiHs.495989.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000367378.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

DNASUi2857.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2857.
KEGGihsa:2857.

Organism-specific databases

CTDi2857.
PharmGKBiPA28878.

Phylogenomic databases

eggNOGiENOG410IH53. Eukaryota.
ENOG410ZHRR. LUCA.
HOVERGENiHBG063715.
KOiK08383.
OMAiYHAFRFV.
OrthoDBiEOG091G0DKA.

Miscellaneous databases

GenomeRNAii2857.

Gene expression databases

BgeeiENSG00000171659.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5VT14_HUMAN
AccessioniPrimary (citable) accession number: Q5VT14
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 2, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.