SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5VSR9

- SPXN1_HUMAN

UniProt

Q5VSR9 - SPXN1_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Sperm protein associated with the nucleus on the X chromosome N1
Gene
SPANXN1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm protein associated with the nucleus on the X chromosome N1
Alternative name(s):
Nuclear-associated protein SPAN-Xn1
Short name:
SPANX-N1
SPANX family member N1
Gene namesi
Name:SPANXN1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:33174. SPANXN1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162404376.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7272Sperm protein associated with the nucleus on the X chromosome N1
PRO_0000285538Add
BLAST

Proteomic databases

PaxDbiQ5VSR9.
PRIDEiQ5VSR9.

Expressioni

Gene expression databases

BgeeiQ5VSR9.
CleanExiHS_SPANXN1.
GenevestigatoriQ5VSR9.

Structurei

3D structure databases

ProteinModelPortaliQ5VSR9.

Family & Domainsi

Sequence similaritiesi

Belongs to the SPAN-X family.

Phylogenomic databases

eggNOGiNOG136441.
HOGENOMiHOG000015252.
HOVERGENiHBG097736.
OMAiEYSTVLA.
OrthoDBiEOG7C2R2W.
PhylomeDBiQ5VSR9.
TreeFamiTF341404.

Family and domain databases

InterProiIPR010007. SPANX_prot.
[Graphical view]
PANTHERiPTHR23425. PTHR23425. 1 hit.
PfamiPF07458. SPAN-X. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VSR9-1 [UniParc]FASTAAdd to Basket

« Hide

MEQPTSSING EKRKSPCESN NENDEMQETP NRDLAPEPSL KKMKTSEYST   50
VLAFCYRKAK KIHSNQLEND QS 72
Length:72
Mass (Da):8,263
Last modified:December 7, 2004 - v1
Checksum:i9248A461D75DDA5F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY825029 Genomic DNA. Translation: AAV97585.1.
DQ336121 mRNA. Translation: ABC61872.1.
DQ336118 mRNA. Translation: ABC61869.1.
DQ336119 mRNA. Translation: ABC61870.1.
DQ336120 mRNA. Translation: ABC61871.1.
AL356499, AL713923 Genomic DNA. Translation: CAI42585.1.
AL713923, AL356499 Genomic DNA. Translation: CAH70536.1.
CCDSiCCDS35421.1.
RefSeqiNP_001009614.1. NM_001009614.2.
UniGeneiHs.551270.

Genome annotation databases

EnsembliENST00000370493; ENSP00000359524; ENSG00000203923.
ENST00000600554; ENSP00000470279; ENSG00000269436.
GeneIDi494118.
KEGGihsa:494118.
UCSCiuc004fcb.2. human.

Polymorphism databases

DMDMi74746835.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY825029 Genomic DNA. Translation: AAV97585.1 .
DQ336121 mRNA. Translation: ABC61872.1 .
DQ336118 mRNA. Translation: ABC61869.1 .
DQ336119 mRNA. Translation: ABC61870.1 .
DQ336120 mRNA. Translation: ABC61871.1 .
AL356499 , AL713923 Genomic DNA. Translation: CAI42585.1 .
AL713923 , AL356499 Genomic DNA. Translation: CAH70536.1 .
CCDSi CCDS35421.1.
RefSeqi NP_001009614.1. NM_001009614.2.
UniGenei Hs.551270.

3D structure databases

ProteinModelPortali Q5VSR9.
ModBasei Search...

Polymorphism databases

DMDMi 74746835.

Proteomic databases

PaxDbi Q5VSR9.
PRIDEi Q5VSR9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000370493 ; ENSP00000359524 ; ENSG00000203923 .
ENST00000600554 ; ENSP00000470279 ; ENSG00000269436 .
GeneIDi 494118.
KEGGi hsa:494118.
UCSCi uc004fcb.2. human.

Organism-specific databases

CTDi 494118.
GeneCardsi GC0XP144328.
HGNCi HGNC:33174. SPANXN1.
MIMi 300664. gene.
neXtProti NX_Q5VSR9.
PharmGKBi PA162404376.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG136441.
HOGENOMi HOG000015252.
HOVERGENi HBG097736.
OMAi EYSTVLA.
OrthoDBi EOG7C2R2W.
PhylomeDBi Q5VSR9.
TreeFami TF341404.

Miscellaneous databases

NextBioi 111806.
PROi Q5VSR9.
SOURCEi Search...

Gene expression databases

Bgeei Q5VSR9.
CleanExi HS_SPANXN1.
Genevestigatori Q5VSR9.

Family and domain databases

InterProi IPR010007. SPANX_prot.
[Graphical view ]
PANTHERi PTHR23425. PTHR23425. 1 hit.
Pfami PF07458. SPAN-X. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids."
    Kouprina N., Mullokandov M., Rogozin I.B., Collins N.K., Solomon G., Otstot J., Risinger J.I., Koonin E.V., Barrett J.C., Larionov V.
    Proc. Natl. Acad. Sci. U.S.A. 101:3077-3082(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27."
    Kouprina N., Pavlicek A., Noskov V.N., Solomon G., Otstot J., Isaacs W., Carpten J.D., Trent J.M., Schleutker J., Barrett J.C., Jurka J., Larionov V.
    Genome Res. 15:1477-1486(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiSPXN1_HUMAN
AccessioniPrimary (citable) accession number: Q5VSR9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 7, 2004
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi