Q5VRY0 (RH39_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DEAD-box ATP-dependent RNA helicase 39
EC=3.6.4.13

Gene names

Ordered Locus Names:	Os01g0184500, LOC_Os01g08930
ORF Names:	P0510F03.6

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	625 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + H2O = ADP + phosphate.
Domain	The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence similarities	Belongs to the DEAD box helicase family. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding RNA-binding
Molecular function	Helicase Hydrolase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 625	625	DEAD-box ATP-dependent RNA helicase 39		PRO_0000282515
Regions
	Domain	141 – 328	188	Helicase ATP-binding
	Domain	353 – 503	151	Helicase C-terminal
	Nucleotide binding	154 – 161	8	ATP By similarity
	Motif	110 – 138	29	Q motif
	Motif	268 – 271	4	DEAD box
	Compositional bias	31 – 37	7	Poly-Thr
	Compositional bias	89 – 96	8	Poly-Gly
Experimental info
	Sequence conflict	319	1	D → G in AK060699. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q5VRY0 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: AE71A3E2CBAAD320	FASTA	625	67,860
	10 20 30 40 50 60 MAMAGAAGRC LMLTRPSPLL RLRLLRAALA TTTTTTTAAG ASAVTAPTEP ETTAREAPSR 70 80 90 100 110 120 HELLLERLRQ RHLKGVPAAT PRPAQREKGR GGGGGGAQEL QQKRRVEVVD SFEELGLGEE 130 140 150 160 170 180 VMAALGEMGI SKPTEIQCVG VPAVLAGTSV VLGSHTGSGK TLAYLLPLVQ LLRRDEAMLG 190 200 210 220 230 240 MSMKPRRPRA VVLCPTRELT EQVFRVAKSI SHHARFRSTM VSGGSRIRPQ EDSLNMPVDM 250 260 270 280 290 300 VVGTPGRILD HIKDGNMVYG DIKYLVLDEA DTMFDQGFGP DIRKFLAPLK NRAAKPGDQG 310 320 330 340 350 360 FQTVLVTATM TKAVQKLIDE EFEGIVHLRT TTFQKRVATA RHDFIKLSGS ENKLEALLQV 370 380 390 400 410 420 LEPSLAKGNK VMVFCNTLNS SRAVDHFLTE NQISTVNYHG EVPAEERVEN LNKFRNEEGD 430 440 450 460 470 480 CPTLVCTDLA ARGLDLDVDH VIMFDFPSNS IDYLHRTGRT ARMGAKGKVT SLVAKKDVTL 490 500 510 520 530 540 ATRIEEAMKK NESLEALTTN NVRRAAVNPQ YTSTKGRPSA LKVVNQKGRR GVALQTKSSR 550 560 570 580 590 600 IVKDTTSSRR RSPIRSQPRS KSTSSGKAKP VRSAKPSKSS SPSPKVAKSR PRPEGRKGDA 610 620 LNKLGSKLSV VGFRGRSSGK SAQAS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed: 18089549] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP002486 Genomic DNA. Translation: BAD67795.1. AP008207 Genomic DNA. Translation: BAF04148.1. AK060699 mRNA. No translation available.
RefSeq	NP_001042234.1. NM_001048769.1.
UniGene	Os.3774.
3D structure databases
HSSP	HSSP built from PDB template 1VEC based on UniProtKB P26196.
ProteinModelPortal	Q5VRY0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5VRY0.
Proteomic databases
PRIDE	Q5VRY0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os01g08930.1; LOC_Os01g08930.1; LOC_Os01g08930.
GeneID	4325344.
KEGG	osa:4325344.
Organism-specific databases
Gramene	Q5VRY0.
Phylogenomic databases
GeneTree	EPGT00070000029329.
HOGENOM	HBG737336.
OMA	MKPRRPR.
PhylomeDB	Q5VRY0.
ProtClustDB	CLSN2690824.
Family and domain databases
InterPro	IPR014001. DEAD-like_helicase. IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR001650. Helicase_C. IPR014014. RNA_helicase_DEAD_Q_motif. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF00271. Helicase_C. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS00039. DEAD_ATP_HELICASE. False negative. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS51195. Q_MOTIF. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RH39_ORYSJ

Accession

Primary (citable) accession number: Q5VRY0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2007
Last sequence update:	December 7, 2004
Last modified:	October 19, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program