Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q5VP69 (MPK16_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitogen-activated protein kinase 16

Short name=MAP kinase 16
EC=2.7.11.24
Gene names
Name:MPK16
Ordered Locus Names:Os01g0643800, LOC_Os01g45620
ORF Names:P0510C12.37, P0707D10.2
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length501 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation

Activated by threonine and tyrosine phosphorylation By similarity.

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Post-translational modification

Dually phosphorylated on Thr-184 and Tyr-186, which activates the enzyme By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Contains 1 protein kinase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 501501Mitogen-activated protein kinase 16
PRO_0000239759

Regions

Domain22 – 313292Protein kinase
Nucleotide binding28 – 369ATP By similarity
Motif184 – 1863TXY

Sites

Active site1481Proton acceptor By similarity
Binding site511ATP By similarity

Amino acid modifications

Modified residue1841Phosphothreonine By similarity
Modified residue1861Phosphotyrosine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5VP69 [UniParc].

Last modified December 7, 2004. Version 1.
Checksum: 291499BB20C5C959

FASTA50157,099
        10         20         30         40         50         60 
MDAKKGSGEP EFFSEYGDAS RYEVTEVVGK GSYGVVAAAV DTHTGGRVAI KKINDVFEHI 

        70         80         90        100        110        120 
SDATRILREI KLLRLLRHPD IVEIKHIMLP PSRREFRDIY IIFELMESDL HQVIKANDDL 

       130        140        150        160        170        180 
TPEHHQFFLY QLLRGMKYIH AASVFHRDLK PKNILANADC KVKICDFGLA RVSFDDTPSA 

       190        200        210        220        230        240 
IFWTDYVATR WYRAPELCGS FFSKYTPAID IWSVGCIFAE MLMGKPLFPG KNVVHQLDLM 

       250        260        270        280        290        300 
TDLLGSPSGE TISRIRNEKA RRYLGNMRKK PRVPFSQKFP GADPMALHLL ERLLAFDPKD 

       310        320        330        340        350        360 
RPTAAEALTD PYFTGLANSE REPIAQPISK LEFEFERRKL AKDDVRELIY REILEYHPQM 

       370        380        390        400        410        420 
MQKYLRGGDQ SNFLYPSGVD RFKRQFAHLE EGVAQGDKTS PQLRQHVSLP RERVVRNGDE 

       430        440        450        460        470        480 
PDPTADYCIK LHVGEQPGHS SVTDGLNKPL LSARNFLKSE SIGASQCVVI KEKREKDEES 

       490        500 
MSEYMNEAAD GVPHKIAQLK T 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence and structure of rice chromosome 1."
Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. expand/collapse author list , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[3]"Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
Reyna N.S., Yang Y.
Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP002910 Genomic DNA. Translation: BAD67997.1.
AP003725 Genomic DNA. Translation: BAD68756.1.
AK069424 mRNA. No translation available.
RefSeqNP_001043694.1. NM_001050229.1.
UniGeneOs.34984.

3D structure databases

ProteinModelPortalQ5VP69.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbQ5VP69.
PRIDEQ5VP69.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS01T0643800-01; OS01T0643800-01; OS01G0643800.
GeneID4326567.
KEGGosa:4326567.

Organism-specific databases

GrameneQ5VP69.

Phylogenomic databases

eggNOGCOG0515.
OMAASAVNTH.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPK16_ORYSJ
AccessionPrimary (citable) accession number: Q5VP69
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: December 7, 2004
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations