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Protein
Submitted name:

Gpr7

Gene

LOC571123

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-DRE-375276. Peptide ligand-binding receptors.
R-DRE-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Gpr7Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:LOC571123Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 23

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei45 – 7228HelicalSequence analysisAdd
BLAST
Transmembranei84 – 10421HelicalSequence analysisAdd
BLAST
Transmembranei124 – 14522HelicalSequence analysisAdd
BLAST
Transmembranei166 – 19025HelicalSequence analysisAdd
BLAST
Transmembranei217 – 24024HelicalSequence analysisAdd
BLAST
Transmembranei261 – 27919HelicalSequence analysisAdd
BLAST
Transmembranei299 – 32224HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000044732.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini63 – 319257G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118797.
HOGENOMiHOG000230485.
HOVERGENiHBG106919.
KOiK08377.
OMAiCVWLLVI.
OrthoDBiEOG7BKCVQ.
TreeFamiTF315737.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR009150. Neuropept_B/W_rcpt.
IPR027349. NPBW2.
[Graphical view]
PANTHERiPTHR24229:SF18. PTHR24229:SF18. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01855. NRPEPTIDEWR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5VJN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENITSPFIP NPTCNFSMDL YYHNSFNRSD LNCTPPADYF FYADLYVVLP
60 70 80 90 100
VIYSVICAVG LTGNTAVIYV ILKAPKMKTV TNMFILNLAI ADDLFTLVLP
110 120 130 140 150
INIAEHLLHY WPFGEVLCKI ILSIDHYNIF SSIYFLTVMS VDRYLVVLST
160 170 180 190 200
VRSKRMPYRT YRAAKIVSLC VWLLVILIVM PFSVFAGVYI SPDDTERKSC
210 220 230 240 250
VLSFPSPESL WFKASRIYTL ILGFAIPVST ICILYTMMLY KLRNMRLNTN
260 270 280 290 300
AKALDKAKKK VTIMVFIVLA VCLFCWTPFH LSTIVALTTD LRTTPLLIGI
310 320 330
SYFITSLSYA NSCLNPFLYA FLDDSFRKAF KKMLECRPA
Length:339
Mass (Da):38,705
Last modified:December 7, 2004 - v1
Checksum:iB3BC96F5E71089CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO704896 Genomic DNA. No translation available.
AY429046 Genomic DNA. Translation: AAR88324.1.
RefSeqiNP_001025429.1. NM_001030258.1.
XP_005161996.1. XM_005161939.2.
XP_005161997.1. XM_005161940.2.
UniGeneiDr.94157.

Genome annotation databases

EnsembliENSDART00000044733; ENSDARP00000044732; ENSDARG00000033393.
GeneIDi571123.
KEGGidre:571123.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO704896 Genomic DNA. No translation available.
AY429046 Genomic DNA. Translation: AAR88324.1.
RefSeqiNP_001025429.1. NM_001030258.1.
XP_005161996.1. XM_005161939.2.
XP_005161997.1. XM_005161940.2.
UniGeneiDr.94157.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000044732.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000044733; ENSDARP00000044732; ENSDARG00000033393.
GeneIDi571123.
KEGGidre:571123.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118797.
HOGENOMiHOG000230485.
HOVERGENiHBG106919.
KOiK08377.
OMAiCVWLLVI.
OrthoDBiEOG7BKCVQ.
TreeFamiTF315737.

Enzyme and pathway databases

ReactomeiR-DRE-375276. Peptide ligand-binding receptors.
R-DRE-418594. G alpha (i) signalling events.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR009150. Neuropept_B/W_rcpt.
IPR027349. NPBW2.
[Graphical view]
PANTHERiPTHR24229:SF18. PTHR24229:SF18. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01855. NRPEPTIDEWR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Pharmacological characterization of GPR7 and GPR8 from zebrafish."
    Nothacker H.-P., Civelli O.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  3. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ5VJN3_DANRE
AccessioniPrimary (citable) accession number: Q5VJN3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: July 6, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.