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Q5VIR6

- VPS53_HUMAN

UniProt

Q5VIR6 - VPS53_HUMAN

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Protein
Vacuolar protein sorting-associated protein 53 homolog
Gene
VPS53, PP13624
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.2 Publications

GO - Molecular functioni

  1. protein binding Source: UniProtKB

GO - Biological processi

  1. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 53 homolog
Gene namesi
Name:VPS53
ORF Names:PP13624
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:25608. VPS53.

Subcellular locationi

Golgi apparatustrans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein 2 Publications

GO - Cellular componenti

  1. GARP complex Source: MGI
  2. endosome membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Endosome, Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670618.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 699699Vacuolar protein sorting-associated protein 53 homolog
PRO_0000215189Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei110 – 1101N6-acetyllysine1 Publication
Modified residuei360 – 3601N6-acetyllysine1 Publication
Modified residuei377 – 3771Phosphoserine1 Publication
Modified residuei391 – 3911Phosphothreonine1 Publication
Modified residuei580 – 5801Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ5VIR6.
PaxDbiQ5VIR6.
PRIDEiQ5VIR6.

PTM databases

PhosphoSiteiQ5VIR6.

Expressioni

Gene expression databases

ArrayExpressiQ5VIR6.
BgeeiQ5VIR6.
CleanExiHS_VPS53.
GenevestigatoriQ5VIR6.

Organism-specific databases

HPAiHPA022988.
HPA024446.

Interactioni

Subunit structurei

Component of the Golgi-associated retrograde protein (GARP) complex, also called VFT (VPS fifty-three) complex, composed of VPS51, VPS52, VPS53 and VPS54.1 Publication

Protein-protein interaction databases

BioGridi120563. 13 interactions.
DIPiDIP-59352N.
IntActiQ5VIR6. 2 interactions.
STRINGi9606.ENSP00000401435.

Structurei

3D structure databases

ProteinModelPortaliQ5VIR6.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili55 – 14288 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the VPS53 family.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG327715.
HOGENOMiHOG000265899.
HOVERGENiHBG092351.
InParanoidiQ5VIR6.
OMAiAMSKMPW.
OrthoDBiEOG70PBWZ.
PhylomeDBiQ5VIR6.
TreeFamiTF106150.

Family and domain databases

InterProiIPR007234. Vps53_N.
[Graphical view]
PfamiPF04100. Vps53_N. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q5VIR6-1) [UniParc]FASTAAdd to Basket

Also known as: long

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MMEEEELEFV EELEAVLQLT PEVQLAIEQV FPSQDPLDRA DFNAVEYINT    50
LFPTEQSLAN IDEVVNKIRL KIRRLDDNIR TVVRGQTNVG QDGRQALEEA 100
QKAIQQLFGK IKDIKDKAEK SEQMVKEITR DIKQLDHAKR HLTTSITTLN 150
HLHMLAGGVD SLEAMTRRRQ YGEVANLLQG VMNVLEHFHK YMGIPQIRQL 200
SERVKAAQTE LGQQILADFE EAFPSQGTKR PGGPSNVLRD ACLVANILDP 250
RIKQEIIKKF IKQHLSEYLV LFQENQDVAW LDKIDRRYAW IKRQLVDYEE 300
KYGRMFPREW CMAERIAVEF CHVTRAELAK IMRTRAKEIE VKLLLFAIQR 350
TTNFEGFLAK RFSGCTLTDG TLKKLESPPP STNPFLEDEP TPEMEELATE 400
KGDLDQPKKP KAPDNPFHGI VSKCFEPHLY VYIESQDKNL GELIDRFVAD 450
FKAQGPPKPN TDEGGAVLPS CADLFVYYKK CMVQCSQLST GEPMIALTTI 500
FQKYLREYAW KILSGNLPKT TTSSGGLTIS SLLKEKEGSE VAKFTLEELC 550
LICNILSTAE YCLATTQQLE EKLKEKVDVS LIERINLTGE MDTFSTVISS 600
SIQLLVQDLD AACDPALTAM SKMQWQNVEH VGDQSPYVTS VILHIKQNVP 650
IIRDNLASTR KYFTQFCVKF ANSFIPKFIT HLFKCKPISM VGAEQVRWT 699
Length:699
Mass (Da):79,653
Last modified:December 7, 2004 - v1
Checksum:i6C07EC07682BF4C6
GO
Isoform 2 (identifier: Q5VIR6-2) [UniParc]FASTAAdd to Basket

Also known as: short

The sequence of this isoform differs from the canonical sequence as follows:
     96-124: Missing.

Show »
Length:670
Mass (Da):76,352
Checksum:i8057AAC082136EC7
GO
Isoform 3 (identifier: Q5VIR6-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     656-673: LASTRKYFTQFCVKFANS → PVASTRKYFTQLCVKFAK
     674-699: Missing.

Note: No experimental confirmation available.

Show »
Length:673
Mass (Da):76,569
Checksum:i82C41A7433B5EF79
GO
Isoform 4 (identifier: Q5VIR6-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     696-699: VRWT → LLLDTHSLKM...KLEKLIKKRL

Show »
Length:832
Mass (Da):94,405
Checksum:iEA71D35158E9419E
GO

Sequence cautioni

The sequence AAL55842.1 differs from that shown. Reason: Frameshift at position 562.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti328 – 3281L → I.
Corresponds to variant rs16954056 [ dbSNP | Ensembl ].
VAR_059959
Natural varianti375 – 3751L → R.
Corresponds to variant rs61644407 [ dbSNP | Ensembl ].
VAR_066561

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei96 – 12429Missing in isoform 2.
VSP_016236Add
BLAST
Alternative sequencei656 – 67318LASTR…KFANS → PVASTRKYFTQLCVKFAK in isoform 3.
VSP_016237Add
BLAST
Alternative sequencei674 – 69926Missing in isoform 3.
VSP_016238Add
BLAST
Alternative sequencei696 – 6994VRWT → LLLDTHSLKMVLLDLPSISS QVVRKAPASYTKIVVKGMTR AEMILKVVMAPHEPLVVFVD NYIKLLTDCNTETFQKILDM KGLKRSEQSSMLELLRQRLP APPSGAESSGSLSLTAPTPE QESSRIRKLEKLIKKRL in isoform 4.
VSP_042106

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti27 – 271I → V in ABW03005. 1 Publication
Sequence conflicti115 – 1151K → N in ABW03005. 1 Publication
Sequence conflicti466 – 4661A → T in AAK27973. 1 Publication
Sequence conflicti520 – 5201T → P in AAK27973. 1 Publication
Sequence conflicti525 – 5251G → E in AAK27973. 1 Publication
Sequence conflicti658 – 6658STRKYFTQ → NMAKSHLY in AAL55842. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY444797 mRNA. Translation: AAS20944.1.
AF246287 mRNA. Translation: AAK27973.1.
EU021218 mRNA. Translation: ABW03005.1.
AK001841 mRNA. Translation: BAA91935.1.
AK290343 mRNA. Translation: BAF83032.1.
AC015853 Genomic DNA. No translation available.
AC027455 Genomic DNA. No translation available.
CH471108 Genomic DNA. Translation: EAW90661.1.
BC006116 mRNA. Translation: AAH06116.1.
AF318335 mRNA. Translation: AAL55842.1. Frameshift.
CCDSiCCDS10995.1. [Q5VIR6-2]
CCDS45558.1. [Q5VIR6-4]
RefSeqiNP_001121631.1. NM_001128159.2. [Q5VIR6-4]
NP_060759.2. NM_018289.3. [Q5VIR6-2]
UniGeneiHs.461819.

Genome annotation databases

EnsembliENST00000291074; ENSP00000291074; ENSG00000141252. [Q5VIR6-2]
ENST00000437048; ENSP00000401435; ENSG00000141252. [Q5VIR6-4]
ENST00000571805; ENSP00000459312; ENSG00000141252. [Q5VIR6-1]
GeneIDi55275.
KEGGihsa:55275.
UCSCiuc002frm.2. human. [Q5VIR6-2]
uc002frn.2. human. [Q5VIR6-1]
uc010cjo.2. human. [Q5VIR6-4]

Polymorphism databases

DMDMi74746777.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY444797 mRNA. Translation: AAS20944.1 .
AF246287 mRNA. Translation: AAK27973.1 .
EU021218 mRNA. Translation: ABW03005.1 .
AK001841 mRNA. Translation: BAA91935.1 .
AK290343 mRNA. Translation: BAF83032.1 .
AC015853 Genomic DNA. No translation available.
AC027455 Genomic DNA. No translation available.
CH471108 Genomic DNA. Translation: EAW90661.1 .
BC006116 mRNA. Translation: AAH06116.1 .
AF318335 mRNA. Translation: AAL55842.1 . Frameshift.
CCDSi CCDS10995.1. [Q5VIR6-2 ]
CCDS45558.1. [Q5VIR6-4 ]
RefSeqi NP_001121631.1. NM_001128159.2. [Q5VIR6-4 ]
NP_060759.2. NM_018289.3. [Q5VIR6-2 ]
UniGenei Hs.461819.

3D structure databases

ProteinModelPortali Q5VIR6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 120563. 13 interactions.
DIPi DIP-59352N.
IntActi Q5VIR6. 2 interactions.
STRINGi 9606.ENSP00000401435.

PTM databases

PhosphoSitei Q5VIR6.

Polymorphism databases

DMDMi 74746777.

Proteomic databases

MaxQBi Q5VIR6.
PaxDbi Q5VIR6.
PRIDEi Q5VIR6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000291074 ; ENSP00000291074 ; ENSG00000141252 . [Q5VIR6-2 ]
ENST00000437048 ; ENSP00000401435 ; ENSG00000141252 . [Q5VIR6-4 ]
ENST00000571805 ; ENSP00000459312 ; ENSG00000141252 . [Q5VIR6-1 ]
GeneIDi 55275.
KEGGi hsa:55275.
UCSCi uc002frm.2. human. [Q5VIR6-2 ]
uc002frn.2. human. [Q5VIR6-1 ]
uc010cjo.2. human. [Q5VIR6-4 ]

Organism-specific databases

CTDi 55275.
GeneCardsi GC17M000381.
H-InvDB HIX0013386.
HGNCi HGNC:25608. VPS53.
HPAi HPA022988.
HPA024446.
neXtProti NX_Q5VIR6.
PharmGKBi PA142670618.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG327715.
HOGENOMi HOG000265899.
HOVERGENi HBG092351.
InParanoidi Q5VIR6.
OMAi AMSKMPW.
OrthoDBi EOG70PBWZ.
PhylomeDBi Q5VIR6.
TreeFami TF106150.

Miscellaneous databases

ChiTaRSi VPS53. human.
GenomeRNAii 55275.
NextBioi 59405.
PROi Q5VIR6.

Gene expression databases

ArrayExpressi Q5VIR6.
Bgeei Q5VIR6.
CleanExi HS_VPS53.
Genevestigatori Q5VIR6.

Family and domain databases

InterProi IPR007234. Vps53_N.
[Graphical view ]
Pfami PF04100. Vps53_N. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, SUBUNIT, SUBCELLULAR LOCATION.
  2. "The minimum LOH region defined on chromosome 17p13.3 in human hepatocellular carcinoma with gene content analysis."
    Zhao X., He M., Wan D., Ye Y., He Y., Han L., Guo M., Huang Y., Qin W., Wang M.W., Chong W., Chen J., Zhang L., Yang N., Xu B., Wu M., Zuo L., Gu J.
    Cancer Lett. 190:221-232(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
  3. "Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes."
    Perez-Victoria F.J., Mardones G.A., Bonifacino J.S.
    Mol. Biol. Cell 19:2350-2362(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), SUBCELLULAR LOCATION, FUNCTION.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 332-699.
    Tissue: Placenta and Tongue.
  5. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Placenta.
  8. "Large-scale cDNA transfection screening for genes related to cancer development and progression."
    Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X.
    , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J.
    Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-665 (ISOFORM 1).
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-377 AND THR-391, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-110 AND LYS-360, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex."
    Perez-Victoria F.J., Schindler C., Magadan J.G., Mardones G.A., Delevoye C., Romao M., Raposo G., Bonifacino J.S.
    Mol. Biol. Cell 21:3386-3395(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH VPS51.
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-580, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiVPS53_HUMAN
AccessioniPrimary (citable) accession number: Q5VIR6
Secondary accession number(s): A8K2S8
, B3FH42, Q8WYW3, Q9BRR2, Q9BY02, Q9NV25
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: December 7, 2004
Last modified: July 9, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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