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Protein
Submitted name:

Voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 9*

Gene

CACNA1C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 9*Imported
Gene namesi
Name:CACNA1CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3322HelicalSequence analysisAdd
BLAST
Transmembranei179 – 19719HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ5V9X9.

Expressioni

Gene expression databases

BgeeiENSG00000151067.

Structurei

3D structure databases

ProteinModelPortaliQ5V9X9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 4438Ion_transInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000202248.
KOiK04850.

Family and domain databases

InterProiIPR005821. Ion_trans_dom.
IPR005451. VDCC_L_a1csu.
IPR005446. VDCC_L_a1su.
[Graphical view]
PANTHERiPTHR10037:SF188. PTHR10037:SF188. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01630. LVDCCALPHA1.

Sequencei

Sequence statusi: Fragment.

Q5V9X9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VNDAVGRDWP WIYFVTLIII GSFFVLNLVL GVLSGEFSKE REKAKARGDF
60 70 80 90 100
QKLREKQQLE EDLKGYLDWI TQAEDIDPEN EDEGMDEEKP RNRGTPAGML
110 120 130 140 150
DQKKGKFAWF SHSTETHVSM PTSETESVNT ENVAGGDIEG ENCGARLAHR
160 170 180 190 200
ISKSKFSRYW RRWNRFCRRK CRAAVKSNVF YWLVIFLVFL NTLTIASEHY
210
NQPNWLTEVQ
Length:210
Mass (Da):24,402
Last modified:December 7, 2004 - v1
Checksum:i42A944D84CE2BFE1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei210 – 2101Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY562395 mRNA. Translation: AAT67986.1.
RefSeqiNP_955630.3. NM_199460.3.
UniGeneiHs.118262.
Hs.690010.

Genome annotation databases

GeneIDi775.
KEGGihsa:775.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY562395 mRNA. Translation: AAT67986.1.
RefSeqiNP_955630.3. NM_199460.3.
UniGeneiHs.118262.
Hs.690010.

3D structure databases

ProteinModelPortaliQ5V9X9.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ5V9X9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi775.
KEGGihsa:775.

Organism-specific databases

CTDi775.

Phylogenomic databases

HOGENOMiHOG000202248.
KOiK04850.

Miscellaneous databases

ChiTaRSiCACNA1C. human.
GenomeRNAii775.

Gene expression databases

BgeeiENSG00000151067.

Family and domain databases

InterProiIPR005821. Ion_trans_dom.
IPR005451. VDCC_L_a1csu.
IPR005446. VDCC_L_a1su.
[Graphical view]
PANTHERiPTHR10037:SF188. PTHR10037:SF188. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01630. LVDCCALPHA1.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5V9X9_HUMAN
AccessioniPrimary (citable) accession number: Q5V9X9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: September 7, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.